Country

Clinical trials in Italy

Active obesity and GLP-1 studies with at least one location in Italy.

91active studies

65recruiting now

34countries represented

117largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowNot applicable

Impact of Overweight, Obesity, and Lifestyle Changes on Work Performance and Well-Being in Medical Residents

Obesity, OverweightCondition

Obesity and Overweight Status, No Intervention (Observational Assessment)Treatment

Italy1 locations

Fondazione Policlinico Universitario Agostino Gemelli IRCCSSponsor

Updated 2026-09-08 · NCT07677800See eligibility →

Recruiting nowPhase 3

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Diabetes Mellitus, OverweightCondition

NNC0487-0111, Placebo (matched to NNC0487-0111)Treatment

Argentina, Brazil74 locations

Novo Nordisk A/SSponsor

Updated 2026-09-04 · NCT07533175See eligibility →

Recruiting nowNot applicable

EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Patients

Cardiovascular Diseases, Diabete Type 2Condition

Nordic Walking (NW), Standard Rehabilitation (SR)Treatment

Italy1 locations

Fondazione Don Carlo Gnocchi ETSSponsor

Updated 2026-09-03 · NCT05987410See eligibility →

Recruiting nowNot applicable

Interoception and Illness Perception Before and After Bariatric Surgery: Impact on Disordered Eating (Interoceptiv-BAR)

ObesityCondition

Intervention not listedTreatment

Italy1 locations

Fondazione Policlinico Universitario Agostino Gemelli IRCCSSponsor

Updated 2026-09-03 · NCT07594275See eligibility →

Recruiting nowPhase 3

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

ObesityCondition

NNC0487-0111, Placebo (matched to NNC0487-0111)Treatment

Argentina, Australia72 locations

Novo Nordisk A/SSponsor

Updated 2026-08-27 · NCT07503210See eligibility →

Recruiting nowPhase 3

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Obesity, OverweightCondition

Orforglipron, PlaceboTreatment

Belgium, Brazil117 locations

Eli Lilly and CompanySponsor

Updated 2026-08-24 · NCT06672549See eligibility →

Recruiting nowPhase 3

A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

Obesity, OverweightCondition

Orforglipron, PlaceboTreatment

Israel, Italy34 locations

Eli Lilly and CompanySponsor

Updated 2026-08-24 · NCT06672939See eligibility →

Recruiting nowPhase 3

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Obesity, OverweightCondition

NNC0487-0111, Placebo (matched to NNC0487-0111)Treatment

Australia, Bulgaria81 locations

Novo Nordisk A/SSponsor

Updated 2026-08-17 · NCT07509307See eligibility →

Recruiting nowPhase 4

Fibrosis Lessens After Metabolic Surgery

Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver DiseaseCondition

Metabolic surgery, Incretin-Based TherapyTreatment

Brazil, Canada22 locations

The Cleveland ClinicSponsor

Updated 2026-07-31 · NCT06374875See eligibility →

Recruiting nowPhase 3

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Obesity, Knee Osteoarthritis (OA)Condition

NNC0487-0111, Placebo (matched to NNC0487-0111 )Treatment

Australia, Bulgaria82 locations

Novo Nordisk A/SSponsor

Updated 2026-07-09 · NCT07481630See eligibility →

Recruiting nowNot applicable

ASSESSMENT OF THE NATURAL HISTORY AND PROGNOSTIC FACTORS OF THERAPEUTIC RESPONSE IN SUB-PHENOTYPES OF PATIENTS WITH OBESITY: THE BOLOBE STUDY

Obese Adults, Overweight , ObesityCondition

Intervention not listedTreatment

Italy1 locations

IRCCS Azienda Ospedaliero-Universitaria di BolognaSponsor

Updated 2026-06-24 · NCT07666425See eligibility →

Recruiting nowNot applicable

Low Impact Laparoscopy In Bariatric Surgery

Obesity, MorbidCondition

low pneumoperitoneum laparoscopy with microsurgery, standard laparoscopyTreatment

Italy1 locations

Fondazione Policlinico Universitario Campus Bio-MedicoSponsor

Updated 2026-06-18 · NCT07119437See eligibility →

Recruiting nowNot applicable

Effects of Obesity on Physical Abilities and Daily Living Activities in Elderly Adults

Obesity, Sarcopenic ObesityCondition

Fitness tests and questionnairesTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2026-05-29 · NCT07614464See eligibility →

Recruiting nowNot applicable

Effects of Bariatric Surgery on Cardiovascular Risk Profile in Relation to Inflammatory Parameters: Endothelial Phenotyping and Analysis of the Cross-talk Between Adipose Tissue and Endothelium

Obesity (Disorder)Condition

Before bariatric surgery, both blood and biological samples (stool and urine) will be collected. Patients will also undergo a cardiology examinationTreatment

Italy1 locations

Maria Cecilia HospitalSponsor

Updated 2026-05-08 · NCT07131605See eligibility →

Recruiting nowNot applicable

EVOO and Metabolic Liver Health in MASLD

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, OverweightCondition

Oil Supplementation - 3 tablespoons of oil, 9 Tablespoons of OilTreatment

Italy1 locations

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisSponsor

Updated 2026-05-06 · NCT07412444See eligibility →

Recruiting nowNot applicable

Sustainable and Inclusive Use of Alternative Proteins in Mediterranean Supply Chains (CIPROMED)

Food Preferences, Satiety and Food IntakeCondition

Mediterranean Diet with Control Products (chronic phase), Mediterranean Diet with Insect Protein Bread (chronic phase)Treatment

Italy1 locations

University of BolognaSponsor

Updated 2026-05-04 · NCT07553936See eligibility →

Recruiting nowNot applicable

Changes in Taste and Eating Habits Associated With GLP-1 Agonists in Weight Loss Patients

Obesity & Overweight, Taste AlterationsCondition

Intervention not listedTreatment

Italy4 locations

San Raffaele Telematic UniversitySponsor

Updated 2026-04-28 · NCT07229170See eligibility →

Recruiting nowNot applicable

Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

Colorectal Cancer, Early Onset Colorectal CancerCondition

Semi Quantitative Food Frequency Questionnaire (SQFFQ)Treatment

Finland, Germany8 locations

San Raffaele UniversitySponsor

Updated 2026-04-24 · NCT05732623See eligibility →

Recruiting nowNot applicable

Perception of Quality of Life in Patients Undergoing Endoscopic Vertical Gastroplasty

ObesityCondition

Semi-structured interview on quality of lifeTreatment

Italy1 locations

Fondazione Policlinico Universitario Agostino Gemelli IRCCSSponsor

Updated 2026-04-01 · NCT06839677See eligibility →

Recruiting nowNot applicable

Metabolic Effects of a Diet Replaced With Essential Amino Acids

Obesity Morbid, Weight LossCondition

Aminoacid supplementation, PlaceboTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2026-03-31 · NCT06309563See eligibility →

Recruiting nowNot applicable

Whole Body Vibration Effects on Energy Expenditure in Obese Adolescents

ObesityCondition

Multidisciplinary metabolic rehabilitation, Multidisciplinary metabolic rehabilitation + training with WBVETreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2026-03-30 · NCT06800872See eligibility →

Recruiting nowNot applicable

Effects of Two Different Exercise Programs and Diet in Obese Subjects With NAFLD

Obesity, NAFLDCondition

Aerobic Exercise and diet intervention, Hiit and diet interventionTreatment

Italy1 locations

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisSponsor

Updated 2026-03-27 · NCT06186869See eligibility →

Recruiting nowNot applicable

Effect of a Food for Special Medical Purposes on Muscle Mass Preservation During GLP-1 RAs Weight Loss Treatment

Obesity & OverweightCondition

Myosave®, PlaceboTreatment

Italy3 locations

Pharmanutra S.p.a.Sponsor

Updated 2026-03-23 · NCT07393360See eligibility →

Recruiting nowNot applicable

REMS25: Study on the Use of REMS Technology in Diseases Commonly Associated With Reduced Bone Mineral Density (BMD)

Osteogenesis Imperfecta, OsteoporosisCondition

REMSTreatment

Italy1 locations

Meyer Children's Hospital IRCCSSponsor

Updated 2026-02-17 · NCT07412782See eligibility →

Recruiting nowNot applicable

Characterization and Phenotyping of Patients Who Are Offered Drug Therapy for Obesity

Obesity & OverweightCondition

Intervention not listedTreatment

Italy1 locations

IRCCS Azienda Ospedaliero-Universitaria di BolognaSponsor

Updated 2026-02-17 · NCT07414043See eligibility →

Recruiting nowNot applicable

Endoscopic Suture Gastroplasty (ESG) for Treatment of Obese Patients With Endometrial Cancer

Endometrial CancerCondition

Intervention not listedTreatment

Italy2 locations

Centro di Riferimento Oncologico - AvianoSponsor

Updated 2026-02-12 · NCT07397624See eligibility →

Recruiting nowNot applicable

KETO-TUMOR: a Study on Brain Tumors and Central Obesity

Obese Patients, Hypothalamic NeoplasmsCondition

Dietary interventionTreatment

Italy1 locations

Meyer Children's Hospital IRCCSSponsor

Updated 2026-02-09 · NCT07396896See eligibility →

Recruiting nowPhase 4

GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM

T2DM (Type 2 Diabetes Mellitus)Condition

semaglutide, Standard Treatment (Guideline-Based)Treatment

Italy2 locations

Federico II UniversitySponsor

Updated 2026-01-02 · NCT07314684See eligibility →

Recruiting nowNot applicable

Training App for Inhibitory Control Towards Food

Obesity &Amp; Overweight, Bulimia NervosaCondition

Food-specific inhibitory control training delivered through the FoodTraining App, Waiting listTreatment

Italy1 locations

University of PadovaSponsor

Updated 2025-12-30 · NCT07075952See eligibility →

Recruiting nowNot applicable

Follow up Study of Varapodio Trial: Effect of Longevity and Fasting Mimicking Diet on Risk Factors Age Correlated and Biomarkers of Aging

Fat Mass, Risk Factors Cardiovascular DiseaseCondition

fasting mimicking dietTreatment

Italy1 locations

Fondazione Valter LongoSponsor

Updated 2025-12-01 · NCT07255300See eligibility →

Recruiting nowNot applicable

A Multicenter Study for Evaluating a Digital Support System in Childhood Obesity Treatment

Childhood Obesity, Adolescent ObesityCondition

Evira Care treatment, Standard Lifestyle CareTreatment

Italy, Norway5 locations

Karolinska InstitutetSponsor

Updated 2025-10-06 · NCT04917601See eligibility →

Recruiting nowNot applicable

Abnormal Eating and Taste Perception in Subjects With Obesity

ObesityCondition

Intervention not listedTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-10-03 · NCT05772052See eligibility →

Recruiting nowNot applicable

Bariatric Surgery and Modulation of Perceived Satiety

Obesity, MorbidCondition

Sleeve gastrectomy, OverStitch™ Endoscopic Suturing SystemTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-10-03 · NCT05777928See eligibility →

Recruiting nowNot applicable

Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System

Type 1 Diabetes (T1D), Obesity (Disorder)Condition

VLEKTTreatment

Italy1 locations

Azienda Ospedaliero-Universitaria Consorziale Policlinico di BariSponsor

Updated 2025-09-29 · NCT07185555See eligibility →

Recruiting nowNot applicable

Bone Outcomes, Obesity, Sunlight, and Trauma in Children

Pediatric Fractures, Hypovitaminosis DCondition

Intervention not listedTreatment

Italy2 locations

Paracelsus Medical UniversitySponsor

Updated 2025-09-03 · NCT07143552See eligibility →

Recruiting nowNot applicable

SENSing Inner BodiLy State: Understanding the Role of Interoception in obEsity

Obesity, Body RepresentationCondition

The crossmodal dual-taskTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-08-27 · NCT06855251See eligibility →

Recruiting nowNot applicable

Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE"

Obesity, Type2diabetesCondition

Mediterranean diet, Melatonin supplementationTreatment

Italy4 locations

Federico II UniversitySponsor

Updated 2025-08-12 · NCT06236932See eligibility →

Recruiting nowNot applicable

Impact of WBC on Patients With Metabolic or Neurological Diseases or Fibromyalgia (WBC-MeNeFi)

Obesity, FibromyalgiaCondition

Whole-body cryostimulation (WBC), Rehabilitation programTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-08-04 · NCT05443100See eligibility →

Recruiting nowNot applicable

Early Detection of Renal Abnormalities in Metabolically Healthy and Unhealthy Weight Excess"

ObesityCondition

DietTreatment

Italy2 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-08-03 · NCT06338631See eligibility →

Recruiting nowNot applicable

Dissecting the Molecular and Cellular Pathophysiology of Sarcopenic Obesity in the Elderly

Sarcopenic ObesityCondition

clinical evaluation of sarcopenic obesityTreatment

Italy1 locations

IRCCS San RaffaeleSponsor

Updated 2025-06-18 · NCT06320158See eligibility →

Recruiting nowNot applicable

Study of the Steroid Hormone Milieu in Obese Patients

Obesity, MorbidCondition

Intervention not listedTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-05-13 · NCT06341699See eligibility →

Recruiting nowNot applicable

Reprogramming Energy Homeostasis in Overweight Individuals Via Exercise, Cognitive, and Social Training

Obesity and Overweight, Leptin ResistanceCondition

Nutritional Intervention, Physical Activity trainingTreatment

Italy2 locations

Bambino Gesù Hospital and Research InstituteSponsor

Updated 2025-04-17 · NCT06931730See eligibility →

Recruiting nowNot applicable

Changes in the Lipidomic, Immunological and miRNA Profile in Patients Undergoing a Dietary Program or Bariatric Surgery

Obesity, Liver Disease ParenchymalCondition

Nutritional Approach, Surgery ApproachTreatment

Italy1 locations

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisSponsor

Updated 2025-04-04 · NCT06372015See eligibility →

Recruiting nowNot applicable

Comparison of Three Pre-oxygenation Strategies

Emergencies, AnesthesiaCondition

PreoxygenationTreatment

Italy1 locations

Institute of Mountain Emergency MedicineSponsor

Updated 2025-03-28 · NCT06370689See eligibility →

Recruiting nowNot applicable

Type 2 Diabetes, Obesity and Cortisol Excess

Diabetes Mellitus, Type 2, ObesityCondition

1mg DSTTreatment

Italy5 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-03-24 · NCT05759637See eligibility →

Recruiting nowNot applicable

Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study

Heart Failure with Preserved Ejection Fraction (HFPEF), Heart Failure with Reduced Ejection FractionCondition

Aerobic eccentric interventionTreatment

Italy2 locations

Universita di VeronaSponsor

Updated 2025-03-14 · NCT06826963See eligibility →

Recruiting nowNot applicable

Prevalence of Sarcopenic Obesity in COPD

Sarcopenic Obesity, COPDCondition

Intervention not listedTreatment

Italy1 locations

IRCCS San Raffaele RomaSponsor

Updated 2025-02-12 · NCT06822504See eligibility →

Recruiting nowNot applicable

Validation of an Algorithm for the Diagnosis of Sarcopenic Obesity

Sarcopenic ObesityCondition

DXA, ultrasonographyTreatment

Italy1 locations

Elisa GiannettaSponsor

Updated 2025-02-10 · NCT06815978See eligibility →

Recruiting nowNot applicable

Copeptin and Thirst: Possible Predictive Markers of Effectiveness of Bariatric Surgery?

ObesityCondition

Intervention not listedTreatment

Italy1 locations

IRCCS Azienda Ospedaliero-Universitaria di BolognaSponsor

Updated 2025-02-04 · NCT06806787See eligibility →

Recruiting nowNot applicable

Bariatric Endoscopy for Treatment of Obesity

ObesityCondition

Endoscopic gastroplastyTreatment

Italy1 locations

Mater Olbia HospitalSponsor

Updated 2025-02-03 · NCT04854317See eligibility →

Recruiting nowNot applicable

Metacognitive Beliefs in Obese Patients

ObesityCondition

QuestionnairesTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-01-30 · NCT06800911See eligibility →

Recruiting nowNot applicable

Impact of Bariatric Surgery and Liraglutide on Cognitive-Behavioral Markers of Long-Term Weight Loss in Obesity

Obesity and OverweightCondition

Intervention not listedTreatment

Italy1 locations

I.R.C.C.S Ospedale Galeazzi-Sant'AmbrogioSponsor

Updated 2024-12-11 · NCT06720246See eligibility →

Recruiting nowNot applicable

Cardiometabolic Risk of Obese Subjects: Cross-sectional Study

Obesity and Obesity-related Medical Conditions, Cardiovascular RiskCondition

Intervention not listedTreatment

Italy2 locations

IRCCS Azienda Ospedaliero-Universitaria di BolognaSponsor

Updated 2024-12-05 · NCT06714058See eligibility →

Recruiting nowNot applicable

Intragastric Balloon for Treatment of Overweight and Obesity: Which is the Best Filling Volume?

Obese PatientsCondition

Intragastric balloonTreatment

Italy1 locations

Mater Olbia HospitalSponsor

Updated 2024-11-22 · NCT06673550See eligibility →

Recruiting nowNot applicable

Effects of VLCKD in Metabolic Syndrome

Diabetes Mellitus, Type 2, Non-alcoholic Fatty Liver DiseaseCondition

VLCKD diet with replacing meals, Hypocaloric mediterranean DietTreatment

Italy1 locations

Azienda Ospedaliero Universitaria Maggiore della CaritaSponsor

Updated 2024-10-28 · NCT05275608See eligibility →

Recruiting nowNot applicable

Robotic-assisted Versus Conventional Laparoscopic Surgery in Obese Patients With Early Endometrial Cancer

Endometrial Cancer, Endometrial NeoplasmsCondition

Robot-assisted surgery, Laparoscopic surgeryTreatment

Italy1 locations

Fondazione Policlinico Universitario Agostino Gemelli IRCCSSponsor

Updated 2024-10-03 · NCT05974995See eligibility →

Recruiting nowNot applicable

Evaluation of Gut Permeability in Patients Affected by Obesity and NAFLD: Influence of Ketogenic Diet.

Permeability; Increased, NAFLDCondition

Ketogenic DietTreatment

Italy1 locations

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisSponsor

Updated 2024-10-02 · NCT05477212See eligibility →

Recruiting nowNot applicable

Faesiblity and Safety of Endoscopic sLeeve gastrOplasty in Patients With obEsity and nflammatoRy Bowel Disease

Inflammatory Bowel Diseases, ObesityCondition

Observtional StudyTreatment

Italy1 locations

Laterza LucreziaSponsor

Updated 2024-10-01 · NCT06616714See eligibility →

Recruiting nowNot applicable

Global Research Initiative for Patients Screening on MASH

MASH, MASLDCondition

Intervention not listedTreatment

Belgium, Czechia13 locations

Julius ClinicalSponsor

Updated 2024-08-01 · NCT05651724See eligibility →

Recruiting nowNot applicable

Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With Fibrosis

NASH, NAFLDCondition

Very-low-calorie ketogenic diet (VLCKD) with meal replacements, Mediterranean low-calorie diet (LCD)Treatment

Italy1 locations

University of BolognaSponsor

Updated 2024-03-15 · NCT06308757See eligibility →

This page shows the first 60 studies. Use the full search to filter all matches.

Related countries

United States1,107 China326 Canada158 France110 Spain98 Germany95

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.