Clinical trial

Bone Outcomes, Obesity, Sunlight, and Trauma in Children

Recruiting now · Not applicable · 1 countries · Registry ID NCT07143552

Recruiting nowNot applicableObservational

What this study is about

Prospective case-control study of children (3-15 years) after low-energy trauma. We compare serum bone metabolic markers (25OHD, PTH, ALP, calcium, phosphate), BMI/percentile, and dietary calcium intake between fracture and non-fracture presentations. Blood is collected within 7 days (non-fasting; samples on ice for PTH). Primary aim: association of ALP and calcium with fracture status; secondary aims: vitamin D status, BMI percentile, and a composite Bone Risk Score (≥3). Analyses: group comparisons, logistic regression, ROC.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age3 Years to 15 Years

SexAll

Healthy volunteersAccepted

ConditionPediatric Fractures, Hypovitaminosis D, Obesity and Overweight

Full registry criteria

Inclusion Criteria: * 3-15 years; * low-energy trauma; * cases = radiographic fracture; controls = no fracture. Exclusion Criteria: * chronic renal/liver disease; * primary hypo-/hyperparathyroidism; * hypophosphatemic rickets; * neuromuscular disorders; * corticosteroids/bisphosphonates; * unclear diagnosis/treatment.