Clinical trial

Abnormal Eating and Taste Perception in Subjects With Obesity

Recruiting now · Not applicable · 1 countries · Registry ID NCT05772052

Recruiting nowNot applicableObservational

What this study is about

The identification of safe and effective strategies for weight loss and long-term maintenance is critical to reduce the alarming prevalence of obesity worldwide and mitigate obesity-associated health risks. Specifically, Binge Eating (BE) and Food Addiction (FA) behaviors are well known causes of failed weight loss and weight regain. The definitions of their clinical phenotypes are currently evolving. Recent evidence suggests that food choices, behavior and reward may be driven also by taste perception. The hypothesis of this study is that subjects with dysfunctional eating behavior have different taste thresholds compared to obese subjects without eating disorders, and that this characteristic influences food choice and eating behavior. Identifying a difference in the taste thresholds between obese with and without eating disorder will allow us to understand why certain individuals over-consume or binge on densely caloric foods and to give them a tailored dietary treatment so as to maintain weight loss for a long time. The Binge eating and Food Addiction is assessed using Binge Eating Scale and Yale Food Addiction Scale 2.0. Subjects with obesity recruited are divided in 4 groups: without eating disorder, with food addiction (FA), with binge eating (BE) and with FA + BE. In these groups sweet and salty taste will be measured with the 3-Alternative-Forced-Choice method.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 60 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity

Full registry criteria

Inclusion Criteria: * BMI\>30 kg/m2 and \<45 kg/m2 Exclusion Criteria: * uncooperative patients * heavy smokers * pregnancy or recent (in the last 6 months) childbirth * thyroid disorders * presence of endocrine abnormalities associated with obesity * current or recent oral, nasal or sinus infections * major psychiatric disorder even in pharmacological compensation * patients who had undergone bariatric surgery

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

sweet taste recognition thresholdbaseline

The sweet taste recognition threshold is assessed in subjects without eating disorders, with FA,with BE and FA+ BE

salt taste recognition thresholdbaseline

The salt taste recognition threshold is assessed in subjects without eating disorders, with FA,with BE and FA+ BE

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Istituto Auxologico Italiano🇮🇹 Milan, Italy

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Luisa Gilardini, MDContact

Email · Call 0261911