Clinical trial
Copeptin and Thirst: Possible Predictive Markers of Effectiveness of Bariatric Surgery?
Recruiting now · Not applicable · 1 countries · Registry ID NCT06806787
Recruiting nowNot applicableObservational
What this study is about
Prospective, non-pharmacological, spontaneous, single-center, interventional study.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to 65 Years
SexAll
Healthy volunteersNot accepted
ConditionObesity
Full registry criteria
Inclusion Criteria: * BMI ≥ 40 in the absence of comorbidities; BMI ≥ 35 associated with at least one comorbidity * Age ≥ 18 and less than or equal to 65 years * Written informed consent obtained Exclusion Criteria: Contraindications to bariatric surgery: * severe psychiatric illness in the decompensation phase; * drug or alcohol abuse; * patient unwilling to follow periodic checkups and a dietary regimen pregnancy or lactation. Factors that could alter ADH/copeptin: * Obesity induced by other endocrinopathies or medications; * Diabetes mellitus of any type; * Malignant neoplasms or ongoing acute disease; * Organ failure or chronic CNS and kidney disease; * Hydro-electrolyte alterations; * use of drugs that interfere with pituitary-adrenal axis, diuretics, anti-psychotics and psychopharmacological therapies, GLP1 receptor agonists, estro-progestin therapy.
Treatments and study arms
The registry does not list a named intervention.
Primary outcomes
Postoperative Weight Loss and Copeptin Concentration Associationthrough study completion, an average of 1 year
To verify the existence of an association between postoperative weight loss and reduced copeptin concentration in patients with obesity undergoing laparoscopic sleeve gastrectomy surgery.
Correlation Between Copeptin Concentration and Thirst Perceptionthrough study completion, an average of 1 year
To verify the degree of correlation between copeptin concentration and thirst perception in patients with obesity undergoing laparoscopic sleeve gastrectomy surgery.
Study locations
1 locations were listed when this page was built. The first 40 are shown.
IRCCS Azienda Ospedaliero-Universitaria di Bologna🇮🇹 Bologna, Bologna, Italy