Clinical trial

Type 2 Diabetes, Obesity and Cortisol Excess

Recruiting now · Not applicable · 1 countries · Registry ID NCT05759637

Recruiting nowNot applicableObservational

What this study is about

The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with the HidHyCo presence and the HidHyCo prevalence in an adequate sample of obese patients without T2D and the clinical characteristics more frequently associated with the HidHyCo presence.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 75 Years

SexAll

Healthy volunteersNot accepted

ConditionDiabetes Mellitus, Type 2, Obesity, Cortisol; Hypersecretion

Full registry criteria

Inclusion Criteria: patients with T2D and Obesity Exclusion Criteria: * pregnancy/breast feeding, * sleep apnea, * prepuberal onset of hypertension, hormonal hypersecreting adrenal mass, * symptoms of hypercortisolism; * already known secondary hypertension; * conditions associated with increased hypothalamic-pituitary-adrenal (HPA) axis activity, -severe autoimmune/rheumatologic and hematologic diseases, alcoholism, kidney disease (glomerular filtration rate \<60) * drugs influencing the HPA axis activity. For inclusion in Group 2 the presence of T2D will be an exclusion criteria