Country

Clinical trials in Brazil

Active obesity and GLP-1 studies with at least one location in Brazil.

66active studies

32recruiting now

37countries represented

633largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowPhase 3

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

Overweight, ObesityCondition

Eloralintide, PlaceboTreatment

Australia, Belgium187 locations

Eli Lilly and CompanySponsor

Updated 2026-09-08 · NCT07392190See eligibility →

Recruiting nowPhase 3

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Peripheral Arterial DiseaseCondition

Orforglipron, PlaceboTreatment

Argentina, Australia161 locations

Eli Lilly and CompanySponsor

Updated 2026-09-08 · NCT07223593See eligibility →

Recruiting nowPhase 3

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

Osteoarthritis, Overweight or ObesityCondition

Eloralintide, PlaceboTreatment

Argentina, Belgium152 locations

Eli Lilly and CompanySponsor

Updated 2026-09-08 · NCT07353931See eligibility →

Recruiting nowPhase 3

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

Sleep Apnea, Obstructive, ObesityCondition

Eloralintide, PlaceboTreatment

Australia, Brazil115 locations

Eli Lilly and CompanySponsor

Updated 2026-09-08 · NCT07369011See eligibility →

Recruiting nowPhase 3

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

Ulcerative Colitis, Obesity or OverweightCondition

Mirikizumab, MirikizumabTreatment

Austria, Belgium187 locations

Eli Lilly and CompanySponsor

Updated 2026-09-04 · NCT06937086See eligibility →

Recruiting nowPhase 3

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Crohn's Disease, Obesity or OverweightCondition

Mirikizumab, MirikizumabTreatment

Austria, Belgium183 locations

Eli Lilly and CompanySponsor

Updated 2026-09-04 · NCT06937099See eligibility →

Recruiting nowPhase 3

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Diabetes Mellitus, OverweightCondition

NNC0487-0111, Placebo (matched to NNC0487-0111)Treatment

Argentina, Brazil74 locations

Novo Nordisk A/SSponsor

Updated 2026-09-04 · NCT07533175See eligibility →

Recruiting nowPhase 3

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

Obesity, Overweight and/or ObesityCondition

PF-08653944, PlaceboTreatment

Brazil, Canada50 locations

PfizerSponsor

Updated 2026-09-04 · NCT07595549See eligibility →

Recruiting nowPhase 3

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Metabolic Dysfunction Associated SteatohepatitisCondition

Survodutide, Placebo matching survodutideTreatment

Argentina, Australia445 locations

Boehringer IngelheimSponsor

Updated 2026-09-03 · NCT06632457See eligibility →

Recruiting nowNot applicable

Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity

Overweight and Obese Adults, High Intensity Interval Exercise (HIIE)Condition

ExerciseTreatment

Brazil1 locations

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et PathologiquesSponsor

Updated 2026-08-31 · NCT06868862See eligibility →

Recruiting nowPhase 3

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

Obesity or OverweightCondition

AZD6234, PlaceboTreatment

Argentina, Australia212 locations

AstraZenecaSponsor

Updated 2026-08-25 · NCT07784725See eligibility →

Recruiting nowPhase 3

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Obesity, OverweightCondition

Orforglipron, PlaceboTreatment

Belgium, Brazil117 locations

Eli Lilly and CompanySponsor

Updated 2026-08-24 · NCT06672549See eligibility →

Recruiting nowPhase 3

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver FibrosisCondition

Survodutide, PlaceboTreatment

Argentina, Australia528 locations

Boehringer IngelheimSponsor

Updated 2026-08-21 · NCT06632444See eligibility →

Recruiting nowPhase 3

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

Obesity, OverweightCondition

Eloralintide, PlaceboTreatment

Argentina, Australia162 locations

Eli Lilly and CompanySponsor

Updated 2026-08-21 · NCT07321886See eligibility →

Recruiting nowPhase 3

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

Obesity or OverweightCondition

Placebo, EnicepatideTreatment

Argentina, Australia195 locations

Hoffmann-La RocheSponsor

Updated 2026-08-14 · NCT07351045See eligibility →

Recruiting nowPhase 3

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

Obesity or Overweight, Type 2 Diabetes MellitusCondition

Placebo, EnicepatideTreatment

Argentina, Australia193 locations

Hoffmann-La RocheSponsor

Updated 2026-08-14 · NCT07351058See eligibility →

Recruiting nowPhase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

Obstructive Sleep ApneaCondition

Maridebart cafraglutide, PlaceboTreatment

Australia, Brazil57 locations

AmgenSponsor

Updated 2026-08-14 · NCT07226765See eligibility →

Recruiting nowPhase 3

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

Obesity, Obstructive Sleep ApneaCondition

Maridebart cafraglutide, PlaceboTreatment

Australia, Brazil61 locations

AmgenSponsor

Updated 2026-08-04 · NCT07225686See eligibility →

Recruiting nowPhase 4

Fibrosis Lessens After Metabolic Surgery

Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver DiseaseCondition

Metabolic surgery, Incretin-Based TherapyTreatment

Brazil, Canada22 locations

The Cleveland ClinicSponsor

Updated 2026-07-31 · NCT06374875See eligibility →

Recruiting nowPhase 3

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes MellitusCondition

Elecoglipron, SemaglutideTreatment

Argentina, Australia201 locations

AstraZenecaSponsor

Updated 2026-07-14 · NCT07662213See eligibility →

Recruiting nowPhase 3

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

Weight ManagementCondition

Elecoglipron, PlaceboTreatment

Argentina, Australia321 locations

AstraZenecaSponsor

Updated 2026-07-10 · NCT07667803See eligibility →

Recruiting nowNot applicable

Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity

Periodontitis, ObesityCondition

antimicrobial photodynamic therapy (aPDT), ControlTreatment

Brazil1 locations

University of Sao PauloSponsor

Updated 2026-05-04 · NCT06073704See eligibility →

Recruiting nowNot applicable

Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents

Obesity & Overweight, Eating DisordersCondition

TransForm Health ProgramTreatment

Brazil1 locations

University of Sao PauloSponsor

Updated 2026-03-12 · NCT07466069See eligibility →

Recruiting nowPhase 2

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

Chronic Kidney DiseaseCondition

NNC0519-0130, PlaceboTreatment

Argentina, Australia147 locations

Novo Nordisk A/SSponsor

Updated 2026-03-11 · NCT06717698See eligibility →

Recruiting nowNot applicable

Gastric Content in Fasting Volunteers and in Tirzepatide Users: an Observational and Cross-sectional Study

Full Stomach StatusCondition

Ultrasonographic evaluation of gastric contentTreatment

Brazil1 locations

Hospital Israelita Albert EinsteinSponsor

Updated 2026-02-09 · NCT07398222See eligibility →

Recruiting nowNot applicable

Effect of Partial Dietary Replacement From Animal to Plant-Based Protein for Type 2 Diabetes Management

Type 2 Diabetes, OverweightCondition

Control Diet, Plant-based DietTreatment

Brazil1 locations

Hospital de Clinicas de Porto AlegreSponsor

Updated 2026-01-29 · NCT05706155See eligibility →

Recruiting nowPhase 2, Phase 3

Photobiomodulation in Chronic Knee Pain in Patients Who Are in PreRehabilitation for Bariatric Surgery

Chronic Knee Pain, Obesity, MorbidCondition

Photobiomodulation, Standard Physiotherapy TretamentTreatment

Brazil1 locations

University of Nove de JulhoSponsor

Updated 2025-06-06 · NCT05816798See eligibility →

Recruiting nowNot applicable

Systemic Vibratory Therapy and Osteopathic Manipulative Treatment in Individuals With Obesity

ObesityCondition

Systemic vibratory therapy, Osteopathic manipulative treatmentTreatment

Brazil1 locations

Laboratorio de Vibraçoes Mecanicas e Praticas IntegrativasSponsor

Updated 2025-05-14 · NCT06971159See eligibility →

Recruiting nowNot applicable

Research on Effects of Acute Consumption of Nuts in Obese Diabetic Women

Type 2 Diabetes, ObesityCondition

Nuts in the first meeting, Nuts in the second meetingTreatment

Brazil1 locations

Raquel BallarinSponsor

Updated 2025-04-06 · NCT06710340See eligibility →

Recruiting nowNot applicable

Chronic Effect of Fasting

Overweight and ObesityCondition

Caloric restriction only, Caloric restriction plus TRF morningTreatment

Brazil2 locations

Federal University of Minas GeraisSponsor

Updated 2025-03-18 · NCT03574103See eligibility →

Recruiting nowNot applicable

Endoscopic Treatment of Overweight and Mild Obesity with ORBERA365

Obesity, Obesity, MorbidCondition

Non-Adjustable Intragastric Balloon, ORBERA365Treatment

Brazil1 locations

Kaiser Clinic and HospitalSponsor

Updated 2025-01-21 · NCT06785233See eligibility →

Recruiting nowNot applicable

Obesity and Bariatric Surgery According to a Biopsychosocial Perspective.

Obesity, Heart Rate VariabilityCondition

Holter Faros 360° EKG (Bittium Corporation), Beck Depression Inventory (BDI)Treatment

Brazil1 locations

Rio de Janeiro State UniversitySponsor

Updated 2023-07-18 · NCT05950698See eligibility →

Opening soonPhase 3

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

Obesity or Overweight, Weight-Related ComorbidityCondition

AZD6234, PlaceboTreatment

Argentina, Brazil88 locations

AstraZenecaSponsor

Updated 2026-08-20 · NCT07776509See eligibility →

Opening soonPhase 3

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

Orforglipron, DulaglutideTreatment

Belgium, Brazil71 locations

Eli Lilly and CompanySponsor

Updated 2026-08-19 · NCT07668336See eligibility →

Opening soonNot applicable

Rosuvastatin and Losartan Pharmacokinetics After Bariatric Surgery

Obesity & Overweight, Bariatric SurgeryCondition

Rosuvastatin, Losartan (Control)Treatment

Brazil1 locations

Hospital das Clínicas de Ribeirão PretoSponsor

Updated 2026-08-05 · NCT07748273See eligibility →

Opening soonNot applicable

Transit Bipartition After Sleeve Gastrectomy

Obesity & Overweight, Gastroesophageal Reflux (GERD)Condition

Conversion to Intestinal Transit BipartitionTreatment

Brazil1 locations

Hospital das Clínicas de Ribeirão PretoSponsor

Updated 2026-08-03 · NCT07728682See eligibility →

Opening soonNot applicable

Effect of macaúba Oil Combined With Green Exercises

Stress Mental, DyslipidemiaCondition

Macauba oil, PlaceboTreatment

Brazil2 locations

Federal University of Minas GeraisSponsor

Updated 2026-07-20 · NCT07715461See eligibility →

Opening soonPhase 3

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

CagriSema (Cagrilintide B and Semaglutide I), Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)Treatment

Argentina, Brazil56 locations

Novo Nordisk A/SSponsor

Updated 2026-05-28 · NCT07282613See eligibility →

Opening soonNot applicable

High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea

Obesity, Class III, Sleep Apnea, ObstructiveCondition

High-Intensity Progressive Inspiratory Muscle Training (IMT)Treatment

Brazil1 locations

University of the State of Santa CatarinaSponsor

Updated 2026-03-23 · NCT07469280See eligibility →

Opening soonPhase 3

AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Obesity, OverweightCondition

NNC0487-0111, SemaglutideTreatment

Argentina, Brazil120 locations

Novo Nordisk A/SSponsor

Updated 2026-03-12 · NCT07400107See eligibility →

Opening soonNot applicable

Proteomic Analysis of Patients Undergoing Bariatric Surgery

Obesity, Colon CancerCondition

bariatric surgeryTreatment

Brazil1 locations

Universidade Federal de PernambucoSponsor

Updated 2025-01-22 · NCT06787807See eligibility →

Invitation onlyNot applicable

Cities for Better Health Childhood Obesity Prevention Initiative

ObesityCondition

Community-based intervention packagesTreatment

Australia, Brazil6 locations

Novo Nordisk A/SSponsor

Updated 2026-08-21 · NCT06855563See eligibility →

Invitation onlyNot applicable

EFFECTS OF A YERBA MATE EXTRACT IN REDUCING METABOLIC SYNDROME IN OVERWEIGHT INDIVIDUALS

Metabolic Syndrome, DiabetesCondition

Intervention with yerba mate extract or placeboTreatment

Brazil1 locations

Universidade Federal da Fronteira SulSponsor

Updated 2026-05-29 · NCT07000825See eligibility →

Invitation onlyNot applicable

Effect of Laparoscopic Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass on Gastroesophageal Reflux Disease: An 8-Year Prospective Cohort Study

Gastroesophageal Reflux Disease, Morbid ObesityCondition

Intervention not listedTreatment

Brazil1 locations

Clinica GastrobeseSponsor

Updated 2025-09-25 · NCT03692455See eligibility →

Invitation onlyNot applicable

Effects of Different Dietary Interventions on Abdominal Fat Components, Quadriceps Muscles and Cardiometabolic Parameters

Abdominal Obesity, Cardiac DiseaseCondition

Calorie restriction and balanced distribution of macronutrients, Calorie restriction and low-carbohydrate dietTreatment

Brazil1 locations

University of PernambucoSponsor

Updated 2024-10-15 · NCT06320782See eligibility →

Invitation onlyNot applicable

Methyl-donor Nutrient Supplementation and Methylation Profile in Lupus Patients With Obesity

Overweight and Obesity, Lupus ErythematosusCondition

Vitamin B12 + folic acid supplementation, Placebo supplementationTreatment

Brazil1 locations

University of Sao PauloSponsor

Updated 2024-05-02 · NCT05097365See eligibility →

Active, not recruitingPhase 3

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

Non-alcoholic SteatohepatitisCondition

Semaglutide, PlaceboTreatment

Argentina, Australia558 locations

Novo Nordisk A/SSponsor

Updated 2026-09-04 · NCT04822181See eligibility →

Active, not recruitingPhase 3

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels

Cardiovascular DiseaseCondition

Cagrilintide, SemaglutideTreatment

Argentina, Australia633 locations

Novo Nordisk A/SSponsor

Updated 2026-08-31 · NCT05669755See eligibility →

Active, not recruitingNot applicable

AJYR+GV vs RYGB for GERD

Obesity, Morbid, Gastroesophageal Reflux (GERD)Condition

sleeve gastrectomy with Roux-en-Y antrojejunal anastomosis, AJYR+SG, Roux-en-Y gastric bypass, RYGBTreatment

Brazil1 locations

Victor Dib InstituteSponsor

Updated 2026-08-17 · NCT07768202See eligibility →

Active, not recruitingPhase 3

A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

Obesity, OverweightCondition

Orforglipron, PlaceboTreatment

Brazil, China138 locations

Eli Lilly and CompanySponsor

Updated 2026-08-14 · NCT05869903See eligibility →

Active, not recruitingPhase 3

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

Semaglutide, Placebo (semaglutide)Treatment

Brazil, Bulgaria229 locations

Novo Nordisk A/SSponsor

Updated 2026-08-04 · NCT03811561See eligibility →

Active, not recruitingNot applicable

Exercise and Taurine Supplementation on Intramuscular Fat in Older Women With Obesity

Obesity (BMI>30)Condition

Concurrent Exercise Training, TaurineTreatment

Brazil1 locations

University of Sao PauloSponsor

Updated 2026-07-28 · NCT07730255See eligibility →

Active, not recruitingPhase 3

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Type 2 DiabetesCondition

Retatrutide, PlaceboTreatment

Argentina, Brazil76 locations

Eli Lilly and CompanySponsor

Updated 2026-07-20 · NCT06297603See eligibility →

Active, not recruitingPhase 4

Use of Liraglutide in Children Aged 6 to 12 Years With Severe Obesity

Severe Obesity, Cardiovascular FunctionCondition

Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3MlTreatment

Brazil1 locations

University of Sao Paulo General HospitalSponsor

Updated 2026-05-15 · NCT07590219See eligibility →

Active, not recruitingPhase 3

A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight

Type 1 Diabetes, ObesityCondition

Tirzepatide, PlaceboTreatment

Argentina, Brazil146 locations

Eli Lilly and CompanySponsor

Updated 2026-05-12 · NCT06914895See eligibility →

Active, not recruitingNot applicable

Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters

ObesityCondition

Cycle ergometerTreatment

Brazil2 locations

University of Sao PauloSponsor

Updated 2026-05-11 · NCT06579508See eligibility →

Active, not recruitingNot applicable

Eating Window and Sleep Disorders on Glycemic Control, Cardiovascular Risk, and Weight Loss

Type 2 Diabetes Mellitus (T2DM), HypertensionCondition

Comparison of eating windows interventionTreatment

Brazil1 locations

Federal University of São PauloSponsor

Updated 2026-04-24 · NCT06735859See eligibility →

Active, not recruitingNot applicable

Intervention Based on the Dietary Guidelines for the Brazilian Population for the Treatment of Overweight and Obesity

Obesity & Overweight, Overweight (BMI > 25)Condition

Collective Intervention Based on the Dietary Guidelines for the Brazilian Population, Control Group: Individualized CareTreatment

Brazil1 locations

Federal University of Health Science of Porto AlegreSponsor

Updated 2026-04-20 · NCT07538362See eligibility →

Active, not recruitingNot applicable

Impact of GEA Simultaneous to VSG on Post-operative GERD

Obesity, Reflux, GastroesophagealCondition

gastroenteroanastomosis simultaneous to vertical sleeve gastrectomy, vertical sleeve gastrectomyTreatment

Brazil1 locations

Clinica GastrobeseSponsor

Updated 2026-04-17 · NCT07537244See eligibility →

Active, not recruitingNot applicable

Obesity and Aging: Impacts of Nutritional Counseling and Physical Exercise on Telomeres and Senescence Parameters

Aging, ObesityCondition

Combined Training, Nutritional CounselingTreatment

Brazil1 locations

University of Sao PauloSponsor

Updated 2026-03-20 · NCT07479940See eligibility →

This page shows the first 60 studies. Use the full search to filter all matches.

Related countries

United States1,107 China326 Canada158 France110 Spain98 Germany95

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.