Clinical trial

Chronic Effect of Fasting

Recruiting now · Not applicable · 1 countries · Registry ID NCT03574103

Recruiting nowNot applicableInterventional

What this study is about

The aim of the study is to determine if time-restricted feeding (TRF) is an effective dietary strategy to weight loss after 8 weeks intervention. TRF will be compared with an intervention without restriction in time for feeding. Both strategies will be with caloric restriction.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 59 Years

SexFemale

Healthy volunteersAccepted

ConditionOverweight and Obesity

Full registry criteria

Inclusion Criteria: * Females; * Aged between 18 and 59 years old; * Body mass index equal or greater 25 kg/m²; * Agree to sign the informed consent. Exclusion Criteria: * Any chronic health conditions (e.g. chronic renal failure, autoimmune, heart, and liver disease); * Thyroid diseases or medications for its treatment; * Medications known to affect total energy expenditure; * Use of steroids, immunosuppressants or non-steroidal anti-inflammatory drugs, weight-loss medications, oral hypoglycemic agents or insulin and any medications that influence metabolic and/or inflammatory parameters; * Previous surgery for weight loss; * Pregnancy or breast-feeding; * Smoking; * Alcohol use (\>2 doses/day).

Treatments and study arms

Caloric restriction only

Behavioral

Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements), without restriction in time for feeding, for 8 weeks.

Caloric restriction plus TRF morning

Behavioral

Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 12 p.m. to 8 p.m.) and 16 hours of fasting, for 8 weeks.

Caloric restriction plus TRF night

Behavioral

Participants in this group will receive a eating plan with caloric restriction (513 to 770 kcal from estimated energy requirements) and 8 hours for eating (from 8 a.m. to 4 p.m.) and 16 hours of fasting, for 8 weeks.

Primary outcomes

Change in body weightBaseline and weeks 2, 4 and 8

Body weight will be assessed by mechanical scale

Study locations

2 locations were listed when this page was built. The first 40 are shown.

Hospital da Clínicas🇧🇷 Belo Horizonte, Minas Gerais, Brazil

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Adaliene VM Ferreira, PhDContact

Email · Call +553134093680

Hospital das Clínicas🇧🇷 Belo Horizonte, Minas Gerais, Brazil

Open map

Adaliene VM Ferreira, PhDContact

Email · Call +553134093680