Condition

Clinical trials for Metabolic Disease

Active public studies that list Metabolic Disease as a condition.

24active studies

12recruiting now

11countries represented

10largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowNot applicable

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Metabolic Disease, ObesityCondition

NSR IDE-MRI: Research pulse sequencesTreatment

United States3 locations

National Heart, Lung, and Blood Institute (NHLBI)Sponsor

Updated 2026-09-01 · NCT01143454See eligibility →

Recruiting nowNot applicable

Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

Type 2 Diabetes, Insulin ResistanceCondition

Intervention not listedTreatment

United States1 locations

University of MichiganSponsor

Updated 2026-07-13 · NCT06007404See eligibility →

Recruiting nowNot applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Obesity, Liver DiseasesCondition

ESG + lifestyle modification, Lifestyle modificationTreatment

United States2 locations

Pichamol Jirapinyo, MD, MPHSponsor

Updated 2026-06-25 · NCT06138821See eligibility →

Recruiting nowNot applicable

Exercise Effects on Adipose Tissue Structure and Function

Obesity, Metabolic SyndromeCondition

Exercise, No exerciseTreatment

United States1 locations

University of MichiganSponsor

Updated 2026-06-04 · NCT04812314See eligibility →

Recruiting nowNot applicable

Alzheimer"s Imaging Biomarkers in Obesity

Alzheimer Disease, ObesityCondition

Intervention not listedTreatment

United States1 locations

Cyrus A RajiSponsor

Updated 2026-05-11 · NCT05077579See eligibility →

Recruiting nowNot applicable

Metabolic Adaptations to Weight Loss With and Without Exercise

Obesity, Metabolic DiseaseCondition

MICT Exercise, No Exercise (Control)Treatment

United States1 locations

University of MichiganSponsor

Updated 2026-04-14 · NCT05806801See eligibility →

Recruiting nowNot applicable

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

Obesity, Obesity, MorbidCondition

PSAM Treatment PatientsTreatment

United States1 locations

Christopher C. Thompson, MD, MScSponsor

Updated 2026-03-02 · NCT05711758See eligibility →

Recruiting nowNot applicable

HYPERtension Reduction Through WALKing Stairs Versus Brisk Walking

Metabolic Disease, Cardiovascular DiseasesCondition

Stair and brisk walking combined, Brisk walkingTreatment

Sweden4 locations

Karolinska InstitutetSponsor

Updated 2025-12-08 · NCT06952348See eligibility →

Recruiting nowNot applicable

HIIT Effects on Cardiometabolic Health

Obesity, Cardiovascular DiseasesCondition

high-intensity interval training interventionTreatment

United States1 locations

Syracuse UniversitySponsor

Updated 2025-07-23 · NCT05838950See eligibility →

Recruiting nowNot applicable

Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention

Non-Alcoholic Fatty Liver Disease, Obesity, MorbidCondition

Bariatric surgery, Dietitian led life style modification interventionTreatment

Hong Kong1 locations

Chinese University of Hong KongSponsor

Updated 2025-02-13 · NCT03875625See eligibility →

Recruiting nowNot applicable

Conventional Vs Tailored Limb Lengths in Laparoscopic Roux-en Y Gastric Bypass Surgery

Obesity, Metabolic DiseaseCondition

Laparoscopic Roux-en Y Gastric bypass (RYGB)- Conventional approach, Laparoscopic Roux-en Y Gastric bypass (RYGB)- Tailored approachTreatment

India1 locations

GEM Hospital & Research CenterSponsor

Updated 2025-01-03 · NCT06756789See eligibility →

Recruiting nowNot applicable

Metabolic Effects of Bariatric Arterial Embolization vs Bariatric Surgery

Obesity, Type2diabetesCondition

Roux-en-Y gastric By-pass (RYGB) surgery, Bariatric Arterial Embolization (BAE) procedureTreatment

Portugal1 locations

Universidade Nova de LisboaSponsor

Updated 2024-12-11 · NCT05859022See eligibility →

Opening soonPhase 2

VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway

Cardiovascular Diseases, Insulin Sensitivity/ResistanceCondition

Vericiguat 10 MG, PlaceboTreatment

United States1 locations

University of Alabama at BirminghamSponsor

Updated 2026-01-23 · NCT06320951See eligibility →

Opening soonNot applicable

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

Obesity, Obesity, MorbidCondition

Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - BeltTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2025-12-02 · NCT06299644See eligibility →

Opening soonNot applicable

Treatment and Handling Severe Obesity-Related Comorbidities in Adolescents Through Exercise

Adolescent Obesity, Hypertension,EssentialCondition

Treatment and handling obesity-related comorbidities in adolescents through exerciseTreatment

Locations pending0 locations

University of LisbonSponsor

Updated 2024-07-29 · NCT06520800See eligibility →

Opening soonNot applicable

Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC)

Overweight and Obesity, Cardiovascular DiseasesCondition

Nutritional Psycho-Behavioral Reeducation ProgramTreatment

Locations pending0 locations

Groupe Éthique et SantéSponsor

Updated 2023-05-12 · NCT05857319See eligibility →

Invitation onlyNot applicable

Quality of Recovery and Patient Satisfaction After Metabolic Surgery at a Tertiary Hospital in Gauteng (QoRPS-MS)

Obesity, Obesity (Disorder)Condition

Intervention not listedTreatment

South Africa1 locations

Sefako Makgatho Health Sciences UniversitySponsor

Updated 2026-09-04 · NCT07804290See eligibility →

Invitation onlyNot applicable

HIBOC = Hepatic Imaging Biomarkers in Obese Children

Elastography, Shear Wave ElastographyCondition

Intervention not listedTreatment

Sweden1 locations

Sahlgrenska University HospitalSponsor

Updated 2026-05-18 · NCT06463223See eligibility →

Invitation onlyNot applicable

Effects of Different Dietary Interventions on Abdominal Fat Components, Quadriceps Muscles and Cardiometabolic Parameters

Abdominal Obesity, Cardiac DiseaseCondition

Calorie restriction and balanced distribution of macronutrients, Calorie restriction and low-carbohydrate dietTreatment

Brazil1 locations

University of PernambucoSponsor

Updated 2024-10-15 · NCT06320782See eligibility →

Active, not recruitingNot applicable

Healthy Early Life Moments in Singapore

Metabolic Disease, Mental Health Wellness 1Condition

HELMS Lifestyle InterventionTreatment

Singapore1 locations

KK Women's and Children's HospitalSponsor

Updated 2026-08-06 · NCT05207059See eligibility →

Active, not recruitingNot applicable

Direct Measurement of Microstructure of Ingestive Behaviour After Initiation of GLP-1 Receptor Agonist Treatment at Maximum Dose (DIGRAT)

Metabolic Disease, Obesity & OverweightCondition

semaglutide 1 mg weekly injectionTreatment

Ireland1 locations

University College DublinSponsor

Updated 2026-05-15 · NCT07457424See eligibility →

Active, not recruitingNot applicable

Thermogenic Silencer Regulatory Factors in Humans

Obesity, Metabolic DiseaseCondition

Cold Vest Exposure Period, Rewarming Exposure PeriodTreatment

United States1 locations

Rockefeller UniversitySponsor

Updated 2026-04-14 · NCT06424132See eligibility →

Active, not recruitingNot applicable

Molecular Landscape of Complex Lifestyle Modification

Obesity Prevention, ObesityCondition

supervised lifestyle modificationTreatment

Slovakia1 locations

Slovak Academy of SciencesSponsor

Updated 2025-05-01 · NCT06954298See eligibility →

Active, not recruitingNot applicable

Metabotyping of Overweight and Obese Children

Metabolic Disease, Obesity, InfantCondition

MetaSAMPTreatment

Belgium10 locations

University GhentSponsor

Updated 2024-05-16 · NCT04632511See eligibility →

Related conditions

Obesity1,102 Obesity & Overweight220 Overweight205 Overweight and Obesity130 Type 2 Diabetes108 Hypertension107

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.