Country

Clinical trials in Netherlands

Active obesity and GLP-1 studies with at least one location in Netherlands.

50active studies

31recruiting now

23countries represented

62largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowPhase 1

A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants

Overweight, ObesityCondition

RO7795081, PlaceboTreatment

Netherlands1 locations

Hoffmann-La RocheSponsor

Updated 2026-09-03 · NCT06982131See eligibility →

Recruiting nowPhase 1

A Research Study to See How NNC0487-0111 Affects the Body's Energy Use After a Weight Loss in Adults Living With Obesity, Compared to a Low-calorie Diet or Placebo

Overweight, ObesityCondition

NNC0487-0111, PlaceboTreatment

Denmark, Netherlands2 locations

Novo Nordisk A/SSponsor

Updated 2026-09-02 · NCT07757087See eligibility →

Recruiting nowPhase 1

A Study Investigating the Safety, Absorption, Elimination, and the Effect on the Immune System of ACI-19764 in Healthy Participants and in Participants With Cardiovascular Risk Factors

Healthy Participants, ObesityCondition

Placebo, ACI-19764 at dose A1Treatment

Netherlands1 locations

AC Immune SASponsor

Updated 2026-09-02 · NCT07463196See eligibility →

Recruiting nowPhase 1

A Study to See How Safe a New Medicine (NNC6022-0004) is in Healthy People and People Living With Obesity

Obesity, Elevated High-sensitivity C-reactive Protein (hsCRP)Condition

NNC6022-0004, PlaceboTreatment

Netherlands1 locations

Novo Nordisk A/SSponsor

Updated 2026-09-01 · NCT07693868See eligibility →

Recruiting nowNot applicable

Shift Workers' Health Behavior Action Program Across Europe

Night Shift Work, Obesity & OverweightCondition

Combined Lifestyle InterventionTreatment

Germany, Netherlands5 locations

Wageningen UniversitySponsor

Updated 2026-08-20 · NCT07631767See eligibility →

Recruiting nowNot applicable

Weight Reduction in CLBP

Chronic Low-back Pain, Overweight or ObesityCondition

Pain Neuroscience Education, Cognition-targeted exercise therapyTreatment

Belgium, Netherlands2 locations

Vrije Universiteit BrusselSponsor

Updated 2026-08-20 · NCT04824248See eligibility →

Recruiting nowPhase 3

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

Overweight, ObesityCondition

Semaglutide, PlaceboTreatment

Belgium, Bulgaria62 locations

Novo Nordisk A/SSponsor

Updated 2026-08-18 · NCT07770841See eligibility →

Recruiting nowNot applicable

Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity

Healthy, Overweight (BMI > 25)Condition

Probiotic supplementation, PlaceboTreatment

Netherlands1 locations

Maastricht University Medical CenterSponsor

Updated 2026-08-12 · NCT07715955See eligibility →

Recruiting nowNot applicable

Long-Term Effects of Walnut Consumption on Brain Function

Healthy, Brain Insulin SensitivityCondition

WalnutsTreatment

Netherlands1 locations

Maastricht University Medical CenterSponsor

Updated 2026-07-24 · NCT07422220See eligibility →

Recruiting nowNot applicable

How the Body Processes Sugar After Eating, in People With Different Body Weights

Obesity & OverweightCondition

Low-glycemic breakfast (randomized vs high glycemic), High-glycaemic breakfast (randomized vs low glycemic)Treatment

Netherlands1 locations

Wageningen UniversitySponsor

Updated 2026-07-08 · NCT07690176See eligibility →

Recruiting nowNot applicable

DIStal gastriC Bypass OUtcome in Revision SurgEry After Roux-en-y Gastric Bypass

Obesity, Morbid, Weight GainCondition

Distal gastric bypassTreatment

Netherlands8 locations

St. Antonius HospitalSponsor

Updated 2026-04-27 · NCT04894838See eligibility →

Recruiting nowNot applicable

OBESE-HFpEF: Towards Preventing Obesity Related HFpEF

Heart Failure and Preserved Ejection Fraction, Obesity (Disorder)Condition

Intervention not listedTreatment

Netherlands1 locations

Zuyderland Medisch CentrumSponsor

Updated 2026-04-20 · NCT07539766See eligibility →

Recruiting nowNot applicable

Plant-based Protein-rich Weight Loss Intervention in 55+ Adults With Obesity

ObesityCondition

More plant-based protein intake during weight lossTreatment

Netherlands1 locations

Amsterdam University of Applied SciencesSponsor

Updated 2026-02-24 · NCT07429136See eligibility →

Recruiting nowNot applicable

The Effects of a 4-week Supplementation With a Ketogenic Nutrient Mix on 24-hour Substrate Metabolism and Muscle Health

Overweight and ObesityCondition

ketogenic nutritional Supplement, non-ketogenic, isocaloric controlTreatment

Netherlands1 locations

Maastricht University Medical CenterSponsor

Updated 2026-02-09 · NCT07395973See eligibility →

Recruiting nowNot applicable

Targeted Precision Nutrition Strategy To Prevent Chronic Metabolic Diseases

Obesity and Overweight, Pre-diabeticCondition

Optimal Metabotype-specific diet, Sub-optimal dietTreatment

Netherlands2 locations

Maastricht University Medical CenterSponsor

Updated 2026-01-20 · NCT06923644See eligibility →

Recruiting nowNot applicable

Gastro-Intestinal Digestion and Physiology After Bariatric Surgery

Bariatric Surgery, Roux-en Y Gastric BypassCondition

Gastro-intestinal aspiration, TelemetricTreatment

Netherlands1 locations

Universitaire Ziekenhuizen KU LeuvenSponsor

Updated 2026-01-20 · NCT07286968See eligibility →

Recruiting nowNot applicable

Efficacy of Semaglutide s.c. Once-weekly on Weight Loss and Management in Adolescents With Monogenic Obesity in Clinical Practice

Monogenic ObesityCondition

Semaglutide (administered by PDS290 pen-injector)Treatment

France, Germany7 locations

Prof. Dr. Martin WabitschSponsor

Updated 2026-01-08 · NCT07302802See eligibility →

Recruiting nowNot applicable

Hepatic Gene Response to Intravenous Glucose in Obese Patients With and Without MASLD Undergoing Bariatric Surgery

MASLDCondition

[6,6-D2]-labeled glucose (intravenous), Saline (0.9% sodium chloride infusion)Treatment

Netherlands1 locations

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Sponsor

Updated 2026-01-08 · NCT07326865See eligibility →

Recruiting nowNot applicable

Monitoring Nutritional Consequences of Obesity Treatment on Women's Health

Obesity and Obesity-related Medical Conditions, Bariatric SurgeryCondition

Intervention not listedTreatment

Netherlands1 locations

Wageningen University and ResearchSponsor

Updated 2025-07-10 · NCT06945016See eligibility →

Recruiting nowNot applicable

Effects of Protein Supplementation on Brain Function

Brain Vascular Function, Cognitive FunctionCondition

Protein supplementation with an animal-based protein isolate, Protein supplementation with a plant-based protein isolateTreatment

Netherlands1 locations

Maastricht University Medical CenterSponsor

Updated 2025-07-09 · NCT07057245See eligibility →

Recruiting nowNot applicable

The Role of Obesity in Severe COVID-19 Pathophysiology

COVID-19, Antibody COVID-19Condition

VenipunctureTreatment

Netherlands1 locations

Franciscus GasthuisSponsor

Updated 2025-05-16 · NCT06968442See eligibility →

Recruiting nowNot applicable

A Combined Lifestyle Intervention Delivered by Physio/exercise Therapists for Patients with Persistent Low Back Pain and Overweight or Obesity

Low Back PainCondition

Combined lifestyle intervention and LBP care (physiotherapy, exercise therapy)Treatment

Netherlands1 locations

Willeke BoonstraSponsor

Updated 2025-01-24 · NCT06594796See eligibility →

Recruiting nowNot applicable

Screening for Malnutrition in Obese Patients

Overweight and Obese Adults, Malnutrition or Risk of MalnutritionCondition

Intervention not listedTreatment

Netherlands3 locations

HAN University of Applied SciencesSponsor

Updated 2024-11-08 · NCT06626360See eligibility →

Recruiting nowNot applicable

Butyrate-enriched Triglyceride and Diabetes Prevention

Type 2 Diabetes, PreDiabetesCondition

butyrate/hexanoate-enriched triglyceridesTreatment

Netherlands1 locations

Maastricht University Medical CenterSponsor

Updated 2024-10-26 · NCT06384313See eligibility →

Recruiting nowNot applicable

The Microbiome in (Non-) Obese Pregnancy and Pregnancy Outcomes

Obesity, Maternal, Pregnancy ComplicationsCondition

Blood withdrawalTreatment

Netherlands1 locations

Erasmus Medical CenterSponsor

Updated 2024-09-19 · NCT05754645See eligibility →

Recruiting nowPhase 4

DUTCH Weight Control in Atrial Fibrillation Study

Atrial Fibrillation, ObesityCondition

Semaglutide 3.2 MG/ML, PlaceboTreatment

Netherlands1 locations

Rijnstate HospitalSponsor

Updated 2024-09-19 · NCT06184633See eligibility →

Recruiting nowNot applicable

Global Research Initiative for Patients Screening on MASH

MASH, MASLDCondition

Intervention not listedTreatment

Belgium, Czechia13 locations

Julius ClinicalSponsor

Updated 2024-08-01 · NCT05651724See eligibility →

Recruiting nowNot applicable

Comparing 150cm OAGB With 150cm Biliopancreatic Limb RYGB. A Non-inferiority Trial

Bariatric Surgery Candidate, ObesityCondition

OAGB, RYGBTreatment

Netherlands2 locations

FlevoziekenhuisSponsor

Updated 2024-04-23 · NCT04852198See eligibility →

Recruiting nowNot applicable

Effect of Timed-Restricted Eating on Metabolic Health

Obesity, Non-Alcoholic Fatty Liver DiseaseCondition

Early time restricted eating, Late time restricted eatingTreatment

Netherlands1 locations

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Sponsor

Updated 2023-09-29 · NCT06061042See eligibility →

Recruiting nowNot applicable

Predictors of Weight Loss and Metabolic Health After Bariatric Surgery

Obesity, Morbid, Insulin SensitivityCondition

Intervention not listedTreatment

Netherlands3 locations

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Sponsor

Updated 2023-08-14 · NCT05987631See eligibility →

Recruiting nowNot applicable

The European NAFLD Registry

NAFLD, NASHCondition

Intervention not listedTreatment

Belgium, Finland37 locations

Newcastle UniversitySponsor

Updated 2023-01-06 · NCT04442334See eligibility →

Opening soonNot applicable

Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals

Prediabetes, Brain Insulin SensitivityCondition

AvocadosTreatment

Netherlands1 locations

Maastricht University Medical CenterSponsor

Updated 2026-08-27 · NCT07752225See eligibility →

Opening soonNot applicable

Sleep Evaluation Before and After Metabolic Surgery

Obesity & Overweight, Obesity & Overweight SleepCondition

Primary Metabolic SurgeryTreatment

Netherlands1 locations

Catharina Ziekenhuis EindhovenSponsor

Updated 2026-07-10 · NCT07693491See eligibility →

Opening soonNot applicable

Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)

Severe Mental Illness, Depression / Major Depressive DisorderCondition

Semaglutide (SEMA), Exercise moduleTreatment

Austria, Germany5 locations

Ludwig-Maximilians - University of MunichSponsor

Updated 2026-05-14 · NCT07586150See eligibility →

Opening soonNot applicable

Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

Overweight , Obesity, Obesity (Disorder)Condition

TirzepatideTreatment

Netherlands10 locations

Radboud University Medical CenterSponsor

Updated 2026-03-31 · NCT07504172See eligibility →

Opening soonNot applicable

High-Dairy Food Patterns and Gut-Brain Axis

Brain Insulin Sensitivity, Brain Vascular FunctionCondition

High-dairy food pattern, Low-dairy food patternTreatment

Netherlands1 locations

Maastricht University Medical CenterSponsor

Updated 2026-01-21 · NCT07355309See eligibility →

Opening soonNot applicable

Empowering Healthy Lifestyle Personalised Intervention to Prevent and Control Obesity: The HealthyW8 Project

Obesity Prevention, Obesity and OverweightCondition

Intervention GroupTreatment

Bulgaria, Denmark13 locations

Fundació d'investigació Sanitària de les Illes BalearsSponsor

Updated 2025-07-01 · NCT07011368See eligibility →

Invitation onlyPhase 4

Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)

Diabetes Mellitus, Type 2, Liver FibrosisCondition

early time restricted Mediterranean diet, MysimbaTreatment

Netherlands1 locations

Carmen DietvorstSponsor

Updated 2026-04-21 · NCT06845345See eligibility →

Invitation onlyNot applicable

010Fit'R - Healthy Lifestyle Interventions for Children With Overweight

Overweight, ChildrenCondition

010 Fit'R interventionTreatment

Netherlands1 locations

Erasmus Medical CenterSponsor

Updated 2026-02-19 · NCT07419503See eligibility →

Invitation onlyNot applicable

Multivitamin Impact on Micronutrient Status in GLP-1 Users: A Randomized Trial

Weight Loss, Nutritional DeficienciesCondition

Multivitamin Supplementation, PlaceboTreatment

Netherlands2 locations

Erasmus Medical CenterSponsor

Updated 2025-11-19 · NCT07234916See eligibility →

Active, not recruitingNot applicable

Screening Adults With Obesity to Reduce Heart Failure Events

Obesity, Heart FailureCondition

Screening for heart failureTreatment

Netherlands1 locations

Franciscus GasthuisSponsor

Updated 2026-09-03 · NCT06137261See eligibility →

Active, not recruitingPhase 1

A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver

ObesityCondition

BI 456906, SemaglutideTreatment

Netherlands1 locations

Boehringer IngelheimSponsor

Updated 2026-09-02 · NCT05202353See eligibility →

Active, not recruitingPhase 1

A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity

Obesity, OverweightCondition

NNC0638-0355, Placebo (NNC0638-0355)Treatment

Netherlands, United States4 locations

Novo Nordisk A/SSponsor

Updated 2026-08-17 · NCT06577766See eligibility →

Active, not recruitingPhase 3

A Trial of Setmelanotide in Acquired Hypothalamic Obesity

Hypothalamic ObesityCondition

Setmelanotide, PlaceboTreatment

Canada, Germany28 locations

Rhythm Pharmaceuticals, Inc.Sponsor

Updated 2026-08-10 · NCT05774756See eligibility →

Active, not recruitingPhase 2

A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

Overweight, ObesityCondition

Tirzepatide, PlaceboTreatment

Austria, Canada27 locations

Eli Lilly and CompanySponsor

Updated 2026-05-08 · NCT05536804See eligibility →

Active, not recruitingNot applicable

PET-study on the Role of the Reward System in Weight Loss After Bariatric Surgery

ObesityCondition

standardized liquid mixed meal Nutridrink®Treatment

Netherlands1 locations

University Medical Center GroningenSponsor

Updated 2026-04-29 · NCT05359887See eligibility →

Active, not recruitingNot applicable

The Franciscus Obesity NASH Study

NAFLD, NASH - Nonalcoholic SteatohepatitisCondition

NASH screening, Cardiac dysfunction screeningTreatment

Netherlands1 locations

Franciscus GasthuisSponsor

Updated 2025-08-27 · NCT05499949See eligibility →

Active, not recruitingNot applicable

Physical Exercise Prehabilitation Program in MEtabolic SuRgery

Obesity and Overweight, Bariatric SurgeryCondition

Physical exercise prehabilitationTreatment

Netherlands1 locations

FlevoziekenhuisSponsor

Updated 2025-03-28 · NCT06889207See eligibility →

Active, not recruitingNot applicable

The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery

Bariatric Surgery, Morbid ObesityCondition

14-day Low Calorie DietTreatment

Netherlands1 locations

Rijnstate HospitalSponsor

Updated 2025-01-03 · NCT04433338See eligibility →

Active, not recruitingNot applicable

Extending and Banding the Roux-en-Y Gastric Bypass

Morbid ObesityCondition

Standard RYGB, Extended Pouch RYGBTreatment

Netherlands3 locations

Rijnstate HospitalSponsor

Updated 2024-06-21 · NCT05357807See eligibility →

Related countries

United States1,107 China326 Canada158 France110 Spain98 Germany95

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.