Clinical trial

Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity

Opening soon · Not applicable · 1 countries · Registry ID NCT07504172

Opening soonNot applicableObservational

What this study is about

Tirzepatide is one of the new medications for the treatment of obesity. In clinical research people treated with Tirzepatide have weight loss up to 21%. But there is only a little bit of research showing the effect of Tirzepatide in clinical practice. In this retrospective observational study the investigators will evaluate the effectiveness of tirzepatide in routine clinical practice among adults with obesity in the Netherlands.The main questions it aims to answer are: * How much weight do patients lose after six months of treatment with tirzepatide combined with lifestyle coaching? * How is the medication dosed in daily practice? Researchers will use data from electronic health records of patients in multiple outpatient locations of the Dutch Obesity Clinic (NOK, Nederlandse Obesitas Kliniek).

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed
SexAll
Healthy volunteersNot accepted
ConditionOverweight , Obesity, Obesity (Disorder)

Full registry criteria

Inclusion Criteria: * Adults (age ≥18 years old) * A BMI of ≥ 30 kg/m2 or a BMI ≥ 27 kg/m2 with at least one obesity complication (e.g., hypertension, dyslipidaemia) Exclusion Criteria: * Pregnant women or pregnancy during treatment * Previously treated for obesity (with pharmacotherapy, endoscopic treatment or metabolic-bariatric surgery) * Patients with diabetes

Treatments and study arms

Tirzepatide

Drug

Initiating treatment with tirzepatide

Primary outcomes

Weight changeBaseline-6 months

%TWL= (start weight - 6 month weight/baseline weight)\*100%

Study locations

10 locations were listed when this page was built. The first 40 are shown.

NOK clinics🇳🇱 Amsterdam, Netherlands
Puck van den Hooff, MDContact
NOK clinics🇳🇱 Arnhem, Netherlands
NOK clinics🇳🇱 Beverwijk, Netherlands
NOK clinics🇳🇱 Gouda, Netherlands
NOK clinics🇳🇱 Heerlen, Netherlands
NOK clinics🇳🇱 Hoogeveen, Netherlands
NOK clinics🇳🇱 Nieuwegein, Netherlands
NOK clinics🇳🇱 Terneuzen, Netherlands
NOK clinics🇳🇱 The Hague, Netherlands
Puck van den Hooff, MDContact
NOK clinics🇳🇱 Venlo, Netherlands