Clinical trial
Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity
Recruiting now · Not applicable · 1 countries · Registry ID NCT07715955
What this study is about
The goal of this 16-week randomised, placebo-controlled parallel study is to investigate the effect of a newly formed probiotic supplement on satiety and gut microbiota composition in healthy men and women with overweight or obesity form 20-70 years old. The main question it aims to answer is: Does the probiotic supplement increase feelings of satiety and alter gut microbiota composition? Participants will: * Receive a daily dose of 6 g probiotic supplement (packed in sachets of 3 g) or placebo for 16 weeks. * Visit the research unit 3 times at baseline, week 8 and week 16 of the intervention for blood draws and delivering fecal samples. * Keep a study diary to report deviations from their daily habits and fill in food questionnaires.
Basic eligibility
Full registry criteria
Treatments and study arms
Probiotic supplementation
16-week consumption of 6 g/day of probiotic supplement
Placebo
16-week consumption of 6 g/day of placebo
Primary outcomes
The primary objective of the study is to investigate the effects of a combination of specifically selected probiotic strains in a new probiotic formulation on ad libitum food intake, in individuals with overweight and/or obesity. The primary endpoint is the difference in satiety measured by ad libitum food intake comparing the probiotic and control intervention.
Study locations
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