Condition

Clinical trials for Prediabetic State

Active public studies that list Prediabetic State as a condition.

14active studies

7recruiting now

9countries represented

179largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowPhase 1

Human Models of Selective Insulin Resistance: Alpelisib, Part I

Insulin Resistance, Prediabetic StateCondition

Alpelisib 300 mg, PlaceboTreatment

United States1 locations

Columbia UniversitySponsor

Updated 2026-08-24 · NCT06354088See eligibility →

Recruiting nowPhase 1

Effect of Insulin Lowering on Lipogenesis

Hyperinsulinemia, Insulin ResistanceCondition

Placebo, Diazoxide Oral Suspension, 2 mg per kg per doseTreatment

United States1 locations

Columbia UniversitySponsor

Updated 2026-07-06 · NCT07403604See eligibility →

Recruiting nowNot applicable

Time-restricted Eating, Window Timing, Type 2 Diabetes Status and Sex on Glycemic Control

Diabetes Mellitus, Type 2, ObesityCondition

Early (7:00 - 16:00) TRE, Mid (9:30 - 18:30) TRETreatment

Canada1 locations

University of TorontoSponsor

Updated 2026-06-30 · NCT06118931See eligibility →

Recruiting nowNot applicable

Exercise Training and Fat Metabolism in Postmenopausal Women

Postmenopausal Symptoms, ObesityCondition

Resistance Exercise, Endurance ExerciseTreatment

United States1 locations

Florida State UniversitySponsor

Updated 2026-04-13 · NCT05351476See eligibility →

Recruiting nowNot applicable

Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center

Prediabetic State, PreDiabetesCondition

One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los AngelesTreatment

United States1 locations

Cedars-Sinai Medical CenterSponsor

Updated 2026-01-20 · NCT06897982See eligibility →

Recruiting nowNot applicable

PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes

Prediabetic State, Life StyleCondition

Individual intervention condition (PreventT2), Couple-based intervention condition (PreventT2 Together; couple-based adaptation of 2021 PreventT2; approved by the CDC in November 2022 as an Alternate Curriculum for use in the NDPP)Treatment

United States1 locations

University of UtahSponsor

Updated 2025-05-30 · NCT06690788See eligibility →

Recruiting nowNot applicable

Genetics of the Acute Response to Oral Semaglutide

PreDiabetes, Prediabetic StateCondition

Semaglutide PillTreatment

Poland1 locations

Medical University of BialystokSponsor

Updated 2025-03-26 · NCT05340868See eligibility →

Opening soonPhase 3

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

Overweight, Prediabetic StateCondition

Orforglipron, PlaceboTreatment

Argentina, China179 locations

Eli Lilly and CompanySponsor

Updated 2026-08-31 · NCT07794579See eligibility →

Opening soonNot applicable

AI-Driven Metabolic Cohort in Overweight/Obese Chinese Adults

Overweight and Obesity, Diabetes Mellitus, Type 2Condition

Intervention not listedTreatment

Locations pending0 locations

Zhujiang HospitalSponsor

Updated 2026-05-13 · NCT07584330See eligibility →

Opening soonPhase 1

Human Models of Selective Insulin Resistance: Pancreatic Clamp

Insulin Resistance, HyperinsulinemiaCondition

Insulin human, Octreotide AcetateTreatment

United States1 locations

Columbia UniversitySponsor

Updated 2026-02-06 · NCT06558422See eligibility →

Opening soonNot applicable

Enhancing Mental and Physical Health of Women Veterans 3.0

Cardiovascular Diseases, OverweightCondition

EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)Treatment

United States1 locations

VA Office of Research and DevelopmentSponsor

Updated 2026-01-21 · NCT07356479See eligibility →

Active, not recruitingNot applicable

Long-term Health and Economic Effects of an Individualized Lifestyle Intervention (LI-PAD-Extended)

Overweight, ObesityCondition

Individualized physical activity and dietTreatment

Sweden1 locations

Vastra Gotaland RegionSponsor

Updated 2026-08-28 · NCT07605169See eligibility →

Active, not recruitingNot applicable

Enhancing Mental and Physical Health of Women Veterans

Cardiovascular Diseases, OverweightCondition

EBQI, REPTreatment

United States1 locations

VA Office of Research and DevelopmentSponsor

Updated 2026-02-17 · NCT05050266See eligibility →

Active, not recruitingNot applicable

OXXYNEA® GS: Study for Glycaemia Management

Prediabetic State, OverweightCondition

Verum A, Verum BTreatment

Spain1 locations

FytexiaSponsor

Updated 2025-09-18 · NCT05926947See eligibility →

Related conditions

Obesity1,102 Obesity & Overweight220 Overweight205 Overweight and Obesity130 Type 2 Diabetes108 Hypertension107

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.