Condition

Clinical trials for Diabetes Mellitus, Type 2

Active public studies that list Diabetes Mellitus, Type 2 as a condition.

75active studies

38recruiting now

44countries represented

229largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowPhase 2

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

Obesity, OverweightCondition

Macupatide, EloralintideTreatment

Argentina, Australia42 locations

Eli Lilly and CompanySponsor

Updated 2026-09-08 · NCT07215559See eligibility →

Recruiting nowPhase 3

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting

Diabetes Mellitus, Type 2, Diabetes MelletusCondition

OrforglipronTreatment

India, Saudi Arabia40 locations

Eli Lilly and CompanySponsor

Updated 2026-09-08 · NCT07613307See eligibility →

Recruiting nowPhase 3

Semaglutide for Smoking Cessation in Patients With Diabetes

Diabetes Mellitus, Type 2, Nicotine AddictionCondition

Semaglutide, Nicotine replacementTreatment

Canada1 locations

Ottawa Heart Institute Research CorporationSponsor

Updated 2026-09-08 · NCT07059377See eligibility →

Recruiting nowPhase 3

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

Obesity, OverweightCondition

Maridebart Cafraglutide, PlaceboTreatment

Japan, Puerto Rico37 locations

AmgenSponsor

Updated 2026-09-03 · NCT07684144See eligibility →

Recruiting nowPhase 2

A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

UBT251, UBT251 PlaceboTreatment

Australia, Germany70 locations

Novo Nordisk A/SSponsor

Updated 2026-08-10 · NCT07668388See eligibility →

Recruiting nowPhase 2

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

NNC0662-0419, SemaglutideTreatment

Croatia, Hungary63 locations

Novo Nordisk A/SSponsor

Updated 2026-08-10 · NCT07415954See eligibility →

Recruiting nowNot applicable

Surgical TreAtment for Obesity Related Disease and Onco-Metabolic Surgery

Gastric Cancer, Diabetes Mellitus, Type 2Condition

Long limb Roux-en-Y reconstruction after subtotal gastrectomy, Conventional Roux-en-Y reconstruction after subtotal gastrectomyTreatment

South Korea1 locations

Korea University Anam HospitalSponsor

Updated 2026-08-07 · NCT04284943See eligibility →

Recruiting nowNot applicable

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Obesity, Non-Alcoholic Fatty Liver DiseaseCondition

Intervention not listedTreatment

United States1 locations

Bettina MittendorferSponsor

Updated 2026-08-06 · NCT06571474See eligibility →

Recruiting nowPhase 3

Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With Diabetes

Diabetes Mellitus, Type 2Condition

SemaglutideTreatment

United States1 locations

Emory UniversitySponsor

Updated 2026-08-03 · NCT07428746See eligibility →

Recruiting nowNot applicable

Culturally Adapted Dietary Clinical Trial in PR

Diabetes Mellitus, Type 2, ObesityCondition

Culturally tailored food and diet advice, Standard healthy eating adviceTreatment

Puerto Rico1 locations

Harvard School of Public Health (HSPH)Sponsor

Updated 2026-07-28 · NCT05962372See eligibility →

Recruiting nowNot applicable

Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources

PreDiabetes, Diabetes Mellitus, Type 2Condition

Keto-SAT, Keto-CANTreatment

Canada1 locations

University of AlbertaSponsor

Updated 2026-07-16 · NCT05681468See eligibility →

Recruiting nowPhase 1, Phase 2

A First-In-Human Study of ARO-ALK7 in Adults With Obesity With and Without Type 2 Diabetes Mellitus

Obesity, Diabetes Mellitus, Type 2Condition

ARO-ALK7, PlaceboTreatment

Australia, New Zealand8 locations

Arrowhead PharmaceuticalsSponsor

Updated 2026-07-08 · NCT06937203See eligibility →

Recruiting nowNot applicable

Time-restricted Eating, Window Timing, Type 2 Diabetes Status and Sex on Glycemic Control

Diabetes Mellitus, Type 2, ObesityCondition

Early (7:00 - 16:00) TRE, Mid (9:30 - 18:30) TRETreatment

Canada1 locations

University of TorontoSponsor

Updated 2026-06-30 · NCT06118931See eligibility →

Recruiting nowNot applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Obesity, Liver DiseasesCondition

ESG + lifestyle modification, Lifestyle modificationTreatment

United States2 locations

Pichamol Jirapinyo, MD, MPHSponsor

Updated 2026-06-25 · NCT06138821See eligibility →

Recruiting nowPhase 4

Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.

Obesity, Diabetes Mellitus, Type 2Condition

Tirzepatide (LIPOLESS de Laboratorio de Productos Eticos C.E.I.S.A.)Treatment

Paraguay1 locations

Las Rías Medical CenterSponsor

Updated 2026-05-19 · NCT07588438See eligibility →

Recruiting nowNot applicable

Collection of Human Metabolic Tissues

Obesity, Insulin ResistanceCondition

Collection of blood samples and tissuesTreatment

France1 locations

University Hospital, MontpellierSponsor

Updated 2026-05-08 · NCT02861781See eligibility →

Recruiting nowPhase 4

Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

Diabetes Mellitus, Type 2, DiabetesCondition

Insulin resistance testing, OGTTTreatment

United States2 locations

Stanford UniversitySponsor

Updated 2026-04-20 · NCT06657209See eligibility →

Recruiting nowNot applicable

Glucose-dependent INsulinotropic Polypeptide: Effect on Bone Remodelling and Cell Activity (GINEBRA)

Bone Disease, Metabolic, Diabetes Mellitus, Type 2Condition

Glucose-dependent Insulinotropic Polypeptide (GIP)Treatment

Denmark1 locations

Esbjerg Hospital - University Hospital of Southern DenmarkSponsor

Updated 2026-01-02 · NCT06790225See eligibility →

Recruiting nowNot applicable

Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD

Chronic Kidney Disease stage3, Chronic Kidney Disease stage4Condition

GLP-1 receptor agonist, SGLT2 inhibitorTreatment

Spain1 locations

Cardenal Herrera UniversitySponsor

Updated 2025-12-30 · NCT07309094See eligibility →

Recruiting nowNot applicable

Efficacy of mHealth Apps for Health in a Low-income, Type II Diabetic, Hispanic Population

Diabetes Mellitus, Type 2, ObesityCondition

Mobile health applicationTreatment

United States1 locations

San Diego State UniversitySponsor

Updated 2025-10-06 · NCT05279729See eligibility →

Recruiting nowNot applicable

Efficacy of Using Mobile Health Applications for Health

Diabetes Mellitus, Type 2, ObesityCondition

Mobile health applicationTreatment

United States1 locations

San Diego State UniversitySponsor

Updated 2025-10-06 · NCT05589155See eligibility →

Recruiting nowNot applicable

Assessing the Value of Avocados on Glycemic Control in Type 2 Diabetes

Diabetes Mellitus, Type 2, InsulinCondition

Avocado, Other Fruit(s)Treatment

United States1 locations

Pennington Biomedical Research CenterSponsor

Updated 2025-07-31 · NCT05958368See eligibility →

Recruiting nowNot applicable

Bone Health After Bariatric Surgery in Patients With Type 2 Diabetes

Bariatric Surgery, Bone HealthCondition

Bariatric surgeryTreatment

Canada3 locations

CHU de Quebec-Universite LavalSponsor

Updated 2025-06-10 · NCT03455868See eligibility →

Recruiting nowNot applicable

The Poor Responders Study

Bariatric Surgery Candidate, Obesity, MorbidCondition

Gut hormonesTreatment

United Kingdom1 locations

Imperial College LondonSponsor

Updated 2025-05-09 · NCT05404061See eligibility →

Recruiting nowNot applicable

The Acute T-Rex (Timing of Resistance Exercise) Study

Diabetes Mellitus, Type 2, Insulin ResistanceCondition

Resistance Exercise TimingTreatment

United States1 locations

University of UtahSponsor

Updated 2025-04-03 · NCT06366399See eligibility →

Recruiting nowNot applicable

Type 2 Diabetes, Obesity and Cortisol Excess

Diabetes Mellitus, Type 2, ObesityCondition

1mg DSTTreatment

Italy5 locations

Istituto Auxologico ItalianoSponsor

Updated 2025-03-24 · NCT05759637See eligibility →

Recruiting nowNot applicable

Endoscopic Sutured Gastroplasty with Endomina® Device Versus Standard of Care in Patients with Type 2 Diabetes and Class I Obesity: a Multi-center, Randomized Controlled Trial

Diabetes Mellitus, Type 2, ObesityCondition

endomina®Treatment

France1 locations

University Hospital, GrenobleSponsor

Updated 2025-03-14 · NCT05516576See eligibility →

Recruiting nowNot applicable

Cohort Study on Plant-based Diets (COPLANT Study)

Dietary Exposure, Diabetes Mellitus, Type 2Condition

Intervention not listedTreatment

Austria, Germany8 locations

German Federal Institute for Risk AssessmentSponsor

Updated 2025-02-14 · NCT06323538See eligibility →

Recruiting nowNot applicable

The Effect of Bariatric Surgery on Insulin Sensitivity and Energy Metabolism

Obesity, Diabetes Mellitus, Type 2Condition

surgeryTreatment

Germany1 locations

German Diabetes CenterSponsor

Updated 2025-01-10 · NCT01477957See eligibility →

Recruiting nowNot applicable

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

Diabetes Mellitus, Type 2, PreDiabetesCondition

Dietary Intervention Mediterranean Low Carbohydrate Diet, Dietary Intervention Standard Low Carbohydrate DietTreatment

United States1 locations

Stanford UniversitySponsor

Updated 2024-12-04 · NCT05165706See eligibility →

Recruiting nowNot applicable

Effects of VLCKD in Metabolic Syndrome

Diabetes Mellitus, Type 2, Non-alcoholic Fatty Liver DiseaseCondition

VLCKD diet with replacing meals, Hypocaloric mediterranean DietTreatment

Italy1 locations

Azienda Ospedaliero Universitaria Maggiore della CaritaSponsor

Updated 2024-10-28 · NCT05275608See eligibility →

Recruiting nowNot applicable

Evaluation of the Metabolic Surgery Technique for Glycemic Improvement in Type 2 Diabetes

Diabetes Mellitus, Type 2, ObesityCondition

metabolic surgery with SLEEVE technique, metabolic surgery with BY-PASS techniqueTreatment

France1 locations

Médipôle Lyon-VilleurbanneSponsor

Updated 2024-09-19 · NCT06600555See eligibility →

Recruiting nowPhase 4

Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes

Diabetes Mellitus, Type 2, Stroke (CVA) or Transient Ischemic AttackCondition

Semaglutide Auto-Injector, PlaceboTreatment

United States1 locations

University of WashingtonSponsor

Updated 2024-06-05 · NCT05780905See eligibility →

Recruiting nowNot applicable

A UK Registry for Metabolic and Bariatric Endoscopic Interventions

Obesity, Diabetes Mellitus, Type 2Condition

Endoscopic gastric suturing, Endoscopic gastric plicationTreatment

United Kingdom1 locations

Cleveland Clinic LondonSponsor

Updated 2024-03-15 · NCT06305208See eligibility →

Recruiting nowNot applicable

Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland

Diabetes Mellitus, Type 2, Obesity, MorbidCondition

Whole genome sequencing, VAGUSTreatment

Greenland1 locations

Steno Diabetes Center GreenlandSponsor

Updated 2024-02-20 · NCT06264427See eligibility →

Recruiting nowNot applicable

Biomarkers in the Diagnosis and Prognosis of NAFLD

NAFLD, ObesityCondition

Plasma Test, Plasma testTreatment

Italy1 locations

University of TriesteSponsor

Updated 2023-10-24 · NCT06098417See eligibility →

Recruiting nowNot applicable

Who Will Benefit From Bariatric Surgery for Diabetes?

Diabetes Mellitus, Type 2, ObesityCondition

Roux-en-Y gastric bypass (RYGB)Treatment

United Kingdom1 locations

Imperial College LondonSponsor

Updated 2023-04-19 · NCT03842475See eligibility →

Recruiting nowNot applicable

Dietary Strategies for Remission of Type 2 Diabetes

Diabetes Mellitus, Type 2, Overweight and ObesityCondition

Energy restricted diet, Low carbohydrate high fat dietTreatment

Norway1 locations

University of BergenSponsor

Updated 2022-07-08 · NCT04943926See eligibility →

Opening soonPhase 3

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

Obesity or Overweight, Diabetes Mellitus, Type 2Condition

AZD6234, PlaceboTreatment

Argentina, Australia218 locations

AstraZenecaSponsor

Updated 2026-08-25 · NCT07784270See eligibility →

Opening soonPhase 2

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

Atherosclerosis, Cardiovascular DiseaseCondition

Clazakizumab, PlaceboTreatment

Argentina, Japan47 locations

Eli Lilly and CompanySponsor

Updated 2026-08-25 · NCT07783802See eligibility →

Opening soonPhase 3

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

Orforglipron, DulaglutideTreatment

Belgium, Brazil71 locations

Eli Lilly and CompanySponsor

Updated 2026-08-19 · NCT07668336See eligibility →

Opening soonNot applicable

Mazdutide for Remission of Type 2 Diabetes: Multicentre, Double Blind, Randomised, Placebo Controlled Trial

Diabetes Mellitus, Type 2Condition

Mazdutide, PlaceboTreatment

China1 locations

Yanbing LiSponsor

Updated 2026-08-17 · NCT07767552See eligibility →

Opening soonPhase 4

AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetes

Obesity, Diabetes Mellitus, Type 2Condition

AI-Assisted Intensive Lifestyle Intervention, TirzepatideTreatment

China2 locations

The First Affiliated Hospital of Anhui Medical UniversitySponsor

Updated 2026-07-13 · NCT07697391See eligibility →

Opening soonNot applicable

"Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and Obesity Within a Primary Care Context"

Diabetes Mellitus, Type 2, ObesityCondition

Supervised Exercise Training Program, mHealth Unsupervised Exercise Program (ActiVital App)Treatment

Spain1 locations

Escuela Universitaria de OsunaSponsor

Updated 2026-07-06 · NCT07685080See eligibility →

Opening soonPhase 3

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

CagriSema (Cagrilintide B and Semaglutide I), Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)Treatment

Argentina, Brazil56 locations

Novo Nordisk A/SSponsor

Updated 2026-05-28 · NCT07282613See eligibility →

Opening soonNot applicable

AI-Driven Metabolic Cohort in Overweight/Obese Chinese Adults

Overweight and Obesity, Diabetes Mellitus, Type 2Condition

Intervention not listedTreatment

Locations pending0 locations

Zhujiang HospitalSponsor

Updated 2026-05-13 · NCT07584330See eligibility →

Opening soonPhase 3

AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Obesity, OverweightCondition

NNC0487-0111, SemaglutideTreatment

Argentina, Brazil120 locations

Novo Nordisk A/SSponsor

Updated 2026-03-12 · NCT07400107See eligibility →

Opening soonNot applicable

Gut Microbiota, Diet-INDuced Obesity and Type 2 Diabetes in New Caledonia - MIND

Diabetes Mellitus, Type 2, ObesityCondition

25 ml blood sample, Urine sampleTreatment

Locations pending0 locations

Institut PasteurSponsor

Updated 2026-03-09 · NCT07205913See eligibility →

Opening soonNot applicable

Regulatory Post Marketing Surveillance (rPMS) Study of Rybelsus (Oral Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea

Diabetes Mellitus, Type 2Condition

SemaglutideTreatment

Locations pending0 locations

Novo Nordisk A/SSponsor

Updated 2025-12-05 · NCT05714683See eligibility →

Invitation onlyNot applicable

Prevalence and Overlap of Cardiovascular, Kidney, and Metabolic Diseases in Korea: A Population-based Study

Diabetes Mellitus, Type 2, ObesityCondition

No treatment givenTreatment

South Korea1 locations

Novo Nordisk A/SSponsor

Updated 2026-06-29 · NCT07673822See eligibility →

Invitation onlyNot applicable

Regulatory Post Marketing Surveillance (rPMS) Study of Ozempic (Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea

Diabetes Mellitus, Type 2Condition

SemaglutideTreatment

South Korea1 locations

Novo Nordisk A/SSponsor

Updated 2026-05-05 · NCT05689372See eligibility →

Invitation onlyPhase 4

Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)

Diabetes Mellitus, Type 2, Liver FibrosisCondition

early time restricted Mediterranean diet, MysimbaTreatment

Netherlands1 locations

Carmen DietvorstSponsor

Updated 2026-04-21 · NCT06845345See eligibility →

Invitation onlyNot applicable

Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients

Diabetes Mellitus, Type 2, Nicotine Dependence, CigarettesCondition

Application of GLP-1RAs drugs, DPP-4i groupTreatment

China1 locations

Shanghai East HospitalSponsor

Updated 2025-05-31 · NCT06924697See eligibility →

Invitation onlyNot applicable

Diabetes Remission and Hypoabsorptive Bariatric Surgery

Severe Obesity, Diabetes Mellitus, Type 2Condition

Duodenal Switch, SADI-STreatment

Spain1 locations

Hospital Universitari de BellvitgeSponsor

Updated 2023-09-21 · NCT06043245See eligibility →

Invitation onlyNot applicable

An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)

Diabetes, Diabetes Mellitus, Type 2Condition

No treatment givenTreatment

United States1 locations

Novo Nordisk A/SSponsor

Updated 2023-06-13 · NCT01511393See eligibility →

Active, not recruitingPhase 4

A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or Obesity

Diabetes Mellitus, Type 2, ObesityCondition

TirzepatideTreatment

India21 locations

Eli Lilly and CompanySponsor

Updated 2026-08-21 · NCT07438444See eligibility →

Active, not recruitingNot applicable

PA Moves Trial - Patient Participants

Overweight or Obesity, Diabetes Mellitus, Type 2Condition

Physical Activity, Delayed interventionTreatment

United States1 locations

University of PittsburghSponsor

Updated 2026-08-18 · NCT05227105See eligibility →

Active, not recruitingPhase 3

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

Diabetes Mellitus, Type 2Condition

Semaglutide, Placebo (semaglutide)Treatment

Brazil, Bulgaria229 locations

Novo Nordisk A/SSponsor

Updated 2026-08-04 · NCT03811561See eligibility →

Active, not recruitingNot applicable

Weight Loss Clinical Decision Support

Diabetes Mellitus, Type 2, ObesityCondition

BMI-CDSTreatment

United States1 locations

HealthPartners InstituteSponsor

Updated 2026-07-28 · NCT05198765See eligibility →

Active, not recruitingPhase 4

A Study of Cardiovascular Events iN Diabetes Plus

Diabetes Mellitus, Type 2Condition

Semaglutide Oral Tablet, Placebo oral tabletTreatment

United Kingdom1 locations

University of OxfordSponsor

Updated 2026-06-23 · NCT05441267See eligibility →

This page shows the first 60 studies. Use the full search to filter all matches.

Related conditions

Obesity1,102 Obesity & Overweight220 Overweight205 Overweight and Obesity130 Type 2 Diabetes108 Hypertension107

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.