City

Clinical trials near Boston, United States

Active studies with a listed research site in Boston, United States.

76active studies

37recruiting now

15countries represented

137largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowNot applicable

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Endometrial Carcinoma, ObesityCondition

CONCURRENT LAPAROSCOPIC HYSTERECTOMY AND WEIGHT LOSS SURGERY-ReferralTreatment

United States2 locations

Dana-Farber Cancer InstituteSponsor

Updated 2026-08-31 · NCT04839614See eligibility →

Recruiting nowNot applicable

Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity

Obesity & OverweightCondition

Intervention not listedTreatment

United States3 locations

Foundation for the National Institutes of HealthSponsor

Updated 2026-08-20 · NCT07776678See eligibility →

Recruiting nowNot applicable

Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care

Obesity & Overweight, Weight ManagementCondition

Culinary medicine classes, Medically Tailored GroceriesTreatment

United States2 locations

Tufts UniversitySponsor

Updated 2026-07-21 · NCT07717658See eligibility →

Recruiting nowNot applicable

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

Hypertension, DiabetesCondition

Facilitated Transition to Primary CareTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-07-13 · NCT06557005See eligibility →

Recruiting nowPhase 2

Study of Tirzepatide for Recovery and Alcohol Use Management

Alcohol Use Disorder (AUD)Condition

Tirzepatide, Saline PlaceboTreatment

United States2 locations

Brigham and Women's HospitalSponsor

Updated 2026-07-09 · NCT06727331See eligibility →

Recruiting nowPhase 4

GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH

Genetic Predisposition, Metabolic DiseasesCondition

oral semaglutide, Mixed Meal Tolerance Test (MMTT)Treatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-07-08 · NCT06003153See eligibility →

Recruiting nowPhase 2

Oxytocin for Weight Loss in Adolescents

Obesity, Adolescent, OxytocinCondition

Oxytocin nasal spray, PlaceboTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-06-26 · NCT04551482See eligibility →

Recruiting nowNot applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Obesity, Liver DiseasesCondition

ESG + lifestyle modification, Lifestyle modificationTreatment

United States2 locations

Pichamol Jirapinyo, MD, MPHSponsor

Updated 2026-06-25 · NCT06138821See eligibility →

Recruiting nowNot applicable

Trans-nasal Endoscopy for Bariatric Patients

Obesity, Obesity, MorbidCondition

Transnasal Endoscopy, EsophagogastroduodenoscopyTreatment

United States1 locations

Christopher C. Thompson, MD, MScSponsor

Updated 2026-06-25 · NCT06200961See eligibility →

Recruiting nowNot applicable

EVOC - EVs in Obesity and Cardiometabolic Disease

Cardiovascular DiseasesCondition

Intervention not listedTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-06-17 · NCT06408961See eligibility →

Recruiting nowNot applicable

Time Restricted Eating (TRE) in Bipolar Disorder

Bipolar Disorder (BD), Bipolar Disorder DepressionCondition

Time Restricted EatingTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-06-15 · NCT07211217See eligibility →

Recruiting nowNot applicable

Nutrition+: Effect of a High-Protein Diabetes Formula on Body Composition in Type 2 Diabetes Patients Treated With Incretin Mimetics

Type 2 DiabetesCondition

protein supplementTreatment

United States1 locations

Joslin Diabetes CenterSponsor

Updated 2026-05-29 · NCT07271043See eligibility →

Recruiting nowPhase 2

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

HIV-1-infection, FrailtyCondition

Tesamorelin, PlaceboTreatment

United States2 locations

Massachusetts General HospitalSponsor

Updated 2026-05-19 · NCT06554717See eligibility →

Recruiting nowPhase 4

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

Type2Diabetes, ASCVDCondition

SGLT2 inhibitor, GLP-1 receptor agonistTreatment

United States36 locations

Brigham and Women's HospitalSponsor

Updated 2026-04-13 · NCT05390892See eligibility →

Recruiting nowPhase 2

Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity

ObesityCondition

Bimagrumab, TirzepatideTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-03-27 · NCT05933499See eligibility →

Recruiting nowNot applicable

Postnatal Exercise to Activate Baby's Brown Fat

Childhood Obesity Prevention, Childhood ObesityCondition

Active groupTreatment

United States2 locations

Joslin Diabetes CenterSponsor

Updated 2026-03-12 · NCT07467694See eligibility →

Recruiting nowNot applicable

Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease, Non-alcoholic SteatohepatitisCondition

Endoscopic ultrasound shear wave elastographyTreatment

United States2 locations

Brigham and Women's HospitalSponsor

Updated 2026-03-02 · NCT05728697See eligibility →

Recruiting nowNot applicable

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

Obesity, Obesity, MorbidCondition

PSAM Treatment PatientsTreatment

United States1 locations

Christopher C. Thompson, MD, MScSponsor

Updated 2026-03-02 · NCT05711758See eligibility →

Recruiting nowPhase 1

Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors

Colorectal Cancer Prevention, Colorectal AdenomaCondition

TirzepatideTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-02-27 · NCT07095517See eligibility →

Recruiting nowPhase 3

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Hypothalamic Obesity, Multiple Pituitary Hormone Deficiency Genetic FormCondition

Setmelanotide, PlaceboTreatment

United Kingdom, United States11 locations

Rhythm Pharmaceuticals, Inc.Sponsor

Updated 2026-02-12 · NCT06760546See eligibility →

Recruiting nowNot applicable

Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

Obesity, DiabetesCondition

Whole milk, Nonfat milkTreatment

United States1 locations

Boston Children's HospitalSponsor

Updated 2026-01-08 · NCT05464186See eligibility →

Recruiting nowNot applicable

Body Composition and Exercise to Prevent Muscle Loss With GLP1 Agonist Treatment

Obesity, Body CompositionCondition

Smartwatch activity and body composition monitor, General guidance on recommended exerciseTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2025-12-30 · NCT07226947See eligibility →

Recruiting nowNot applicable

Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population

Overweight, PreDiabetesCondition

Bariatrix Meal Replacement ProductsTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2025-12-24 · NCT05799222See eligibility →

Recruiting nowPhase 1, Phase 2

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

Hypothalamic Obesity, Prader-Willi SyndromeCondition

Part A: RM-718 or placebo (matched to specific RM-718 dose cohort), Part B: RM-718 or placebo (matched to specific RM-718 dose cohort)Treatment

United States7 locations

Rhythm Pharmaceuticals, Inc.Sponsor

Updated 2025-12-22 · NCT06239116See eligibility →

Recruiting nowNot applicable

Intermittent Fasting for NAFLD in Adults

Fatty Liver, Intermittent FastingCondition

Time-Restricted, Intermittent FastingTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2025-12-18 · NCT04899102See eligibility →

Recruiting nowNot applicable

Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

Overweight and ObesityCondition

24-hour ambulatory blood pressure, Liberal salt dietTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2025-12-10 · NCT06069622See eligibility →

Recruiting nowNot applicable

Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

Appetitive Behavior, ObesityCondition

Repetitive Transcranial Magnetic Stimulation (rTMS), Sham repetitive Transcranial Magnetic Stimulation (rTMS)Treatment

United States2 locations

Brigham and Women's HospitalSponsor

Updated 2025-12-05 · NCT06105164See eligibility →

Recruiting nowNot applicable

Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline

Overweight, Childhood, Obesity, ChildhoodCondition

CHAMPIONTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2025-11-18 · NCT06432790See eligibility →

Recruiting nowNot applicable

Building Connections

Cancer Colorectal, Cancer CervixCondition

Treatment as Usual, Building Connections InterventionTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2025-11-18 · NCT07091032See eligibility →

Recruiting nowNot applicable

The Physiology of Human Brown Adipose Tissue

Adipose Tissue, Brown, Adipose TissueCondition

Fat biopsy, Blood samplingTreatment

United States1 locations

Beth Israel Deaconess Medical CenterSponsor

Updated 2025-10-31 · NCT04352244See eligibility →

Recruiting nowNot applicable

Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

ObesityCondition

Intervention not listedTreatment

United States2 locations

Columbia UniversitySponsor

Updated 2025-10-21 · NCT01998750See eligibility →

Recruiting nowNot applicable

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Childhood Obesity, Morbid ObesityCondition

Transcriptome profilingTreatment

United States2 locations

Columbia UniversitySponsor

Updated 2025-10-21 · NCT02602769See eligibility →

Recruiting nowPhase 2

Semaglutide for Helping Opioid Recovery

Opioid Use DisorderCondition

Semaglutide, PlaceboTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2025-09-26 · NCT06639464See eligibility →

Recruiting nowNot applicable

Exercise, Brain Activity, and Weight Maintenance

Obesity, Weight GainCondition

ExerciseTreatment

United States1 locations

Joslin Diabetes CenterSponsor

Updated 2025-09-04 · NCT06511310See eligibility →

Recruiting nowNot applicable

Myo-inositol During Pregnancy to Prevent Gestational Diabetes

Pregnancy RelatedCondition

Myo-inositol, Myo-inositol placeboTreatment

United States1 locations

Tufts Medical CenterSponsor

Updated 2025-04-29 · NCT06575868See eligibility →

Recruiting nowNot applicable

International Weight Control Registry

Weight Loss, OverweightCondition

Intervention not listedTreatment

United States7 locations

Tufts UniversitySponsor

Updated 2024-09-19 · NCT04907396See eligibility →

Recruiting nowNot applicable

RESET System Pivotal Trial (Rev F)

Diabetes type2, ObesityCondition

RESET Liner, ShamTreatment

United States7 locations

Morphic Medical Inc.Sponsor

Updated 2024-07-18 · NCT04101669See eligibility →

Opening soonPhase 4

Switching to Oral Weight Management Pharmacotherapy to Prevent Weight Regain After GLP-1 Therapy Discontinuation

ObesityCondition

Phentermine Pill, OrforglipronTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-07-27 · NCT07729332See eligibility →

Opening soonNot applicable

Assessing Follow up Trajectories in Eating, Routines, and Weight After GLP-1

Weight MaintenanceCondition

Digital Behavioral ApplicationTreatment

United States1 locations

Tufts UniversitySponsor

Updated 2026-07-16 · NCT07701460See eligibility →

Opening soonPhase 4

The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression

Bipolar Depression Depressed Phase, Obesity & OverweightCondition

Lumateperone 42 mgTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-07-13 · NCT07699445See eligibility →

Opening soonNot applicable

Inhaled Nitric Oxide in Severe Obesity

Obesity, Respiratory InsufficiencyCondition

Nitric oxideTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-05-20 · NCT06675435See eligibility →

Opening soonNot applicable

Impact of Chia Seeds on Human Breast Milk Composition

Obesity and Overweight, Breastfeeding, ExclusiveCondition

Chia seedsTreatment

United States2 locations

University of OklahomaSponsor

Updated 2026-05-15 · NCT07343908See eligibility →

Opening soonNot applicable

Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth

Dyslipidemia, HypertensionCondition

Nutrition education and produce prescription cardTreatment

United States1 locations

Boston Children's HospitalSponsor

Updated 2026-04-22 · NCT07545005See eligibility →

Opening soonNot applicable

Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss

Obesity, Obesity, MorbidCondition

Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - BeltTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2025-12-02 · NCT06299644See eligibility →

Opening soonNot applicable

Adiposity Distribution in Acute Respiratory Failure

Acute Hypoxemic Respiratory Failure, ObesityCondition

PEEP Titration Using Electrical Impedance Tomography (EIT), Body Positioning: Supine and ProneTreatment

United States1 locations

Maurizio F. Cereda, MDSponsor

Updated 2025-06-13 · NCT07019987See eligibility →

Invitation onlyPhase 2

Setmelanotide to Treat Obesity in a Patient With Pseudohypoparathyroidism Type 1a (PHP1a)

Pseudohypoparathyroidism Type 1a, ObesityCondition

SetmelanotideTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2026-07-23 · NCT07496463See eligibility →

Invitation onlyPhase 2

A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

Hypothalamic ObesityCondition

BivamelagonTreatment

United Kingdom, United States9 locations

Rhythm Pharmaceuticals, Inc.Sponsor

Updated 2026-02-10 · NCT07156578See eligibility →

Invitation onlyNot applicable

Endoscopic Metabolic and Bariatric Therapies

Obesity, Obesity, MorbidCondition

Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical ProceduresTreatment

United States1 locations

Christopher C. Thompson, MD, MScSponsor

Updated 2025-12-02 · NCT05725967See eligibility →

Invitation onlyNot applicable

Risk Informed Obesity Care Plan Pilot

Childhood ObesityCondition

Risk-informed obesity care planTreatment

United States1 locations

Massachusetts General HospitalSponsor

Updated 2025-06-19 · NCT07028814See eligibility →

Active, not recruitingNot applicable

Delta GREENS Food is Medicine Intervention

Cardiometabolic Risk Factors, DiabetesCondition

Food is MedicineTreatment

United States1 locations

Tufts UniversitySponsor

Updated 2026-08-18 · NCT06358859See eligibility →

Active, not recruitingNot applicable

Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study

Cardiovascular Events, Type2 DiabetesCondition

SGLT2 inhibitor, DPP-4 inhibitorTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2026-08-13 · NCT05220917See eligibility →

Active, not recruitingPhase 3

A Trial of Setmelanotide in Acquired Hypothalamic Obesity

Hypothalamic ObesityCondition

Setmelanotide, PlaceboTreatment

Canada, Germany28 locations

Rhythm Pharmaceuticals, Inc.Sponsor

Updated 2026-08-10 · NCT05774756See eligibility →

Active, not recruitingPhase 3

A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight

ObesityCondition

Semaglutide, PlaceboTreatment

Austria, Belgium56 locations

Novo Nordisk A/SSponsor

Updated 2026-08-07 · NCT05726227See eligibility →

Active, not recruitingPhase 2

Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression

Treatment Resistant Depression, InflammationCondition

Omega 3, PlaceboTreatment

United States3 locations

Massachusetts General HospitalSponsor

Updated 2026-07-01 · NCT05774665See eligibility →

Active, not recruitingNot applicable

Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)

Type 2 Diabetes, Heart FailureCondition

Oral semaglutide, SitagliptinTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2026-07-01 · NCT07390110See eligibility →

Active, not recruitingNot applicable

Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity

Obesity, Weight LossCondition

Bariatric Endoscopic Antral MyotomyTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2026-06-25 · NCT05713071See eligibility →

Active, not recruitingPhase 3

A Study of Retatrutide (LY3437943) in Participants Without Type 2 Diabetes Who Have Obesity or Overweight

Obesity, OverweightCondition

RetatrutideTreatment

Argentina, Canada35 locations

Eli Lilly and CompanySponsor

Updated 2026-06-09 · NCT07357415See eligibility →

Active, not recruitingNot applicable

Evaluating the Health Outcomes of the Joslin Why WAIT Program

Diabetes, ObesityCondition

Intervention not listedTreatment

United States1 locations

Joslin Diabetes CenterSponsor

Updated 2026-05-29 · NCT01937845See eligibility →

Active, not recruitingNot applicable

Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction

Type 2 Diabetes, Heart FailureCondition

Tirzepatide, SemaglutideTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2026-05-15 · NCT06980623See eligibility →

Active, not recruitingPhase 4

Lorcaserin in Obesity: Identification of CNS Targets Using fMRI

Obesity, Weight LossCondition

Lorcaserin HCl, PlaceboTreatment

United States1 locations

Beth Israel Deaconess Medical CenterSponsor

Updated 2026-05-01 · NCT02400359See eligibility →

This page shows the first 60 studies. Use the full search to filter all matches.

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.

Clinical trials near Boston, United States

Current studies

Related cities