Condition

Clinical trials for Weight Loss

Active public studies that list Weight Loss as a condition.

82active studies

39recruiting now

15countries represented

137largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowNot applicable

OverStitch NXT Endoscopic Suture System

Weight LossCondition

OverStitch NXT Endoscopic Suture SystemTreatment

China1 locations

Boston Scientific CorporationSponsor

Updated 2026-08-28 · NCT07276815See eligibility →

Recruiting nowNot applicable

Orbera365 Intragastric Balloon System (Abbreviated as'Orbera365')

Weight LossCondition

Treatment groupTreatment

China1 locations

Boston Scientific CorporationSponsor

Updated 2026-08-27 · NCT07195708See eligibility →

Recruiting nowNot applicable

The Role of Microbiome in Recurrent Obesity Before and After Antibiotic/Placebo Treatment

Obesity, Weight LossCondition

Antibiotic treatment, PlaceboTreatment

Israel1 locations

Weizmann Institute of ScienceSponsor

Updated 2026-08-11 · NCT06681246See eligibility →

Recruiting nowNot applicable

Effects of GLP-1 RAs on Human Lactation Outcomes

Lactation, Weight LossCondition

Injected GLP-1 Receptor Agonists and Dual AgonistsTreatment

United States1 locations

University of Colorado, DenverSponsor

Updated 2026-07-22 · NCT07720414See eligibility →

Recruiting nowNot applicable

Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity

Obesity and Overweight, Obese AdolescentsCondition

Ozempic®Treatment

United States1 locations

John BauerSponsor

Updated 2026-07-21 · NCT06967389See eligibility →

Recruiting nowNot applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Obesity, Liver DiseasesCondition

ESG + lifestyle modification, Lifestyle modificationTreatment

United States2 locations

Pichamol Jirapinyo, MD, MPHSponsor

Updated 2026-06-25 · NCT06138821See eligibility →

Recruiting nowPhase 2, Phase 3

Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure

Heart Failure With Reduced Ejection Fraction, ObesityCondition

Semaglutide Injectable Product, Calorie-restricted dietTreatment

Denmark1 locations

Jens D Hove, MD,PHDSponsor

Updated 2026-06-23 · NCT06423599See eligibility →

Recruiting nowNot applicable

Exercise Effects on Adipose Tissue Structure and Function

Obesity, Metabolic SyndromeCondition

Exercise, No exerciseTreatment

United States1 locations

University of MichiganSponsor

Updated 2026-06-04 · NCT04812314See eligibility →

Recruiting nowNot applicable

Metabolic Health, Bones and Nuts During Weight Loss in Adults

Weight Loss, Bone DensityCondition

Peanut Snack Experimental, Nut-free SnackTreatment

United States1 locations

Rutgers, The State University of New JerseySponsor

Updated 2026-05-13 · NCT06949280See eligibility →

Recruiting nowPhase 1

Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)

Alcohol Use Disorder, Weight LossCondition

Semaglutide 1.0 mgTreatment

United States1 locations

Yale UniversitySponsor

Updated 2026-05-12 · NCT07223983See eligibility →

Recruiting nowNot applicable

Testing a Tailored Approach to Long-Term Weight Loss Success

Weight Loss, Weight RegainCondition

Adaptive weight regain preventionTreatment

United States1 locations

University of UtahSponsor

Updated 2026-05-11 · NCT07577765See eligibility →

Recruiting nowNot applicable

Changes in Taste and Eating Habits Associated With GLP-1 Agonists in Weight Loss Patients

Obesity & Overweight, Taste AlterationsCondition

Intervention not listedTreatment

Italy4 locations

San Raffaele Telematic UniversitySponsor

Updated 2026-04-28 · NCT07229170See eligibility →

Recruiting nowNot applicable

Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function

Obesity, Weight LossCondition

Weight loss without pharmacotherapyTreatment

United States1 locations

University of Colorado, BoulderSponsor

Updated 2026-04-28 · NCT06776081See eligibility →

Recruiting nowNot applicable

Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry

Obesity, Weight LossCondition

Endoscopic Bariatric TherapiesTreatment

United States1 locations

Weill Medical College of Cornell UniversitySponsor

Updated 2026-04-23 · NCT04494048See eligibility →

Recruiting nowPhase 2

Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults

Obesity Prevention, Sarcopenia in ElderlyCondition

TirzepatideTreatment

United States1 locations

The University of Texas Health Science Center at San AntonioSponsor

Updated 2026-04-15 · NCT06811324See eligibility →

Recruiting nowNot applicable

Family COMIDA (Consumo de Opciones Más Ideales De Alimentos) (Eating More Ideal Food Options)

Obesity, Child ObesityCondition

Parent Weekly Individual Telephone Support, Child EducationTreatment

United States1 locations

Memorial Sloan Kettering Cancer CenterSponsor

Updated 2026-04-15 · NCT07144800See eligibility →

Recruiting nowNot applicable

Metabolic Adaptations to Weight Loss With and Without Exercise

Obesity, Metabolic DiseaseCondition

MICT Exercise, No Exercise (Control)Treatment

United States1 locations

University of MichiganSponsor

Updated 2026-04-14 · NCT05806801See eligibility →

Recruiting nowNot applicable

The Impact of Lifestyle Intervention on Weight and Fertility in Obese Males

Obesity, Weight LossCondition

Low-carbohydrate diet group, Health Education GroupTreatment

China1 locations

Third Affiliated Hospital of Zhengzhou UniversitySponsor

Updated 2026-04-13 · NCT06339840See eligibility →

Recruiting nowNot applicable

Metabolic Effects of a Diet Replaced With Essential Amino Acids

Obesity Morbid, Weight LossCondition

Aminoacid supplementation, PlaceboTreatment

Italy1 locations

Istituto Auxologico ItalianoSponsor

Updated 2026-03-31 · NCT06309563See eligibility →

Recruiting nowPhase 2

Fasted vs. Fed State Exercise

Obesity, ExerciseCondition

16 week exercise interventionTreatment

United States1 locations

Arkansas Colleges of Health EducationSponsor

Updated 2026-03-23 · NCT07487090See eligibility →

Recruiting nowNot applicable

Probiotic Intervention on Body Weight

Obesity, HomeostasisCondition

General lifestyle and nutritional education, Energy-restricted nutritional and lifestyle interventionTreatment

China1 locations

Chinese Academy of SciencesSponsor

Updated 2026-03-17 · NCT06989177See eligibility →

Recruiting nowNot applicable

Protein Supplementation Intervention on Body Weight

Obesity, Weight LossCondition

General lifestyle and nutritional education, Calorie-restricted balanced dietTreatment

China1 locations

Chinese Academy of SciencesSponsor

Updated 2026-03-17 · NCT06989203See eligibility →

Recruiting nowPhase 4

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

Bipolar I Disorder, Bipolar II DisorderCondition

Group Therapy Program, semaglutideTreatment

United States1 locations

Mayo ClinicSponsor

Updated 2026-03-11 · NCT07213466See eligibility →

Recruiting nowNot applicable

Effect of a Postbiotic Supplementation in Overweight and Obese Subjects: A Randomized Controlled Trial (PARABIOTICS-2).

Nutrition, Healthy, Weight LossCondition

Postbiotic + nutritional recommendations, Placebo + nutritional recommendationsTreatment

Spain1 locations

Clinica Universidad de Navarra, Universidad de NavarraSponsor

Updated 2026-02-19 · NCT07165431See eligibility →

Recruiting nowNot applicable

WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)

Diabetes, Weight LossCondition

tVNS, Complete VagotomyTreatment

United States1 locations

University of FloridaSponsor

Updated 2026-02-10 · NCT06861790See eligibility →

Recruiting nowPhase 4

Evaluating Anti-Obesity Medications 6 Months After Metabolic Surgery

Obesity, Weight LossCondition

Efsubaglutide Alfa Injection, Diet and exercise guidelinesTreatment

China1 locations

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolSponsor

Updated 2026-01-27 · NCT07163650See eligibility →

Recruiting nowNot applicable

Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

Obesity Prevention, Weight ChangeCondition

Reduced Food Variety (RFV), Home-based Resistance Training (HBRT)Treatment

United States1 locations

University of Alabama at BirminghamSponsor

Updated 2026-01-07 · NCT06785064See eligibility →

Recruiting nowNot applicable

Time Restricted Eating for WeIght LoSs MainTenance-2

Weight Loss, Weight GainCondition

TRE, Weight-Loss Maintenance AdviceTreatment

United States1 locations

NYU Langone HealthSponsor

Updated 2025-12-26 · NCT07190170See eligibility →

Recruiting nowNot applicable

BrainWeighve App Feasibility Study

Weight Loss, Obesity and OverweightCondition

BrainWeighve AppTreatment

United States1 locations

University of California, Los AngelesSponsor

Updated 2025-12-22 · NCT05530538See eligibility →

Recruiting nowNot applicable

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

Obesity and Overweight, Diabetes MellitusCondition

Family Skills Training Session Quantity: 5, Family Skills Training Session Mode: In-personTreatment

United States1 locations

University of North Carolina, Chapel HillSponsor

Updated 2025-08-29 · NCT06724406See eligibility →

Recruiting nowPhase 4

Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity

Obesity, Weight LossCondition

Contrave, PlaceboTreatment

Canada3 locations

The Royal's Institute of Mental Health ResearchSponsor

Updated 2025-07-24 · NCT06809166See eligibility →

Recruiting nowNot applicable

Mobile Applet for Weight Management in Obese Heart Failure Patients

Heart Failure, Overweight and ObesityCondition

Full usage of diet management app group and with the full usage of an intelligent weight scale, Limited usage of diet management app group and with the limited usage of an intelligent weight scaleTreatment

China26 locations

Heart Health Research CenterSponsor

Updated 2025-06-27 · NCT06455878See eligibility →

Recruiting nowNot applicable

Lifestyle Changes in Older Adults With Metabolic Syndrome and Tinnitus

Tinnitus, Metabolic Syndrome XCondition

Lifestyle ManagementTreatment

Egypt2 locations

Cairo UniversitySponsor

Updated 2024-11-22 · NCT06702085See eligibility →

Recruiting nowNot applicable

International Weight Control Registry

Weight Loss, OverweightCondition

Intervention not listedTreatment

United States7 locations

Tufts UniversitySponsor

Updated 2024-09-19 · NCT04907396See eligibility →

Recruiting nowPhase 4

DUTCH Weight Control in Atrial Fibrillation Study

Atrial Fibrillation, ObesityCondition

Semaglutide 3.2 MG/ML, PlaceboTreatment

Netherlands1 locations

Rijnstate HospitalSponsor

Updated 2024-09-19 · NCT06184633See eligibility →

Recruiting nowNot applicable

Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery

Bariatric Surgery Candidate, Obesity, MorbidCondition

Intervention not listedTreatment

Spain1 locations

Institut de Recerca Biomèdica de LleidaSponsor

Updated 2024-03-06 · NCT06226194See eligibility →

Recruiting nowNot applicable

Chinese Obesity and MEtabolic Surgery Database (COMES Database)

Obesity, Metabolic SurgeryCondition

Metabolic and Bariatric SurgeryTreatment

China1 locations

Jinan University GuangzhouSponsor

Updated 2024-02-23 · NCT06275061See eligibility →

Recruiting nowNot applicable

PRE-Pregnancy Weight Loss And the Reducing Effect on CHILDhood Overweight - Aarhus

Overweight and Obesity, Weight LossCondition

Weight loss interventionTreatment

Denmark1 locations

Ulla Kampmann OpstrupSponsor

Updated 2024-01-18 · NCT05798494See eligibility →

Recruiting nowNot applicable

Pilot Project on Interdisciplinary Therapy of Obesity

Obesity, Weight LossCondition

Laparoscopic gastric sleeve, Gastric BandingTreatment

Germany3 locations

University of HohenheimSponsor

Updated 2018-10-26 · NCT01344525See eligibility →

Opening soonNot applicable

Reset: Enhancing Weight Loss in a Digital Intervention

Obesity, OverweightCondition

Core Behavioral Weight Loss Intervention, Limit Red Zone FoodsTreatment

United States1 locations

Stanford UniversitySponsor

Updated 2026-08-04 · NCT07032571See eligibility →

Opening soonNot applicable

High-protein plUs reSistance Training in gLucagon-like pEptide 1 Receptor Agonist Users (HUSTLE)

Weight LossCondition

High protein diet, Resistance Training (RT) ProgramsTreatment

United States1 locations

NYU Langone HealthSponsor

Updated 2026-07-13 · NCT07700030See eligibility →

Opening soonNot applicable

Scalable Behavioral Program for Weight Loss Maintenance After GLP-1 and Anti-Obesity Medication Discontinuation

Weight Loss, GLP - 1Condition

Weight Loss Maintenance Program (Foundational), Mom's MealsTreatment

United States1 locations

University of Alabama at BirminghamSponsor

Updated 2026-06-26 · NCT07535892See eligibility →

Opening soonNot applicable

Simplifying Diet Tracking in a Digital Weight Loss Intervention

Overweight, ObesityCondition

Simplified Dietary Self-Monitoring, Detailed Dietary Self-MonitoringTreatment

United States1 locations

Stanford UniversitySponsor

Updated 2026-05-28 · NCT07601061See eligibility →

Opening soonNot applicable

GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study

Obesity & Overweight, Weight LossCondition

Noom Weight, Free TierTreatment

United States1 locations

Noom Inc.Sponsor

Updated 2026-05-15 · NCT07588984See eligibility →

Opening soonNot applicable

Gastric Ultrasound in Patients Who Have Undergone Bariatric Surgery

Obesity, Weight LossCondition

Gastric Point of Care UltrasoundTreatment

United States1 locations

Icahn School of Medicine at Mount SinaiSponsor

Updated 2025-12-30 · NCT07310875See eligibility →

Opening soonNot applicable

Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy

Lower Urinary Tract Symptoms, Stress Urinary IncontinenceCondition

Bariatric Surgery, GLP1 receptor agonistTreatment

United States1 locations

Hartford HealthCareSponsor

Updated 2025-09-16 · NCT07175805See eligibility →

Opening soonPhase 3

Semaglutide Treatment in Type 1 Diabetes

Obesity in Diabetes, Obesity/TherapyCondition

Semaglutide 2.4mg, Semaglutide placeboTreatment

Denmark1 locations

Nordsjaellands HospitalSponsor

Updated 2025-08-08 · NCT06909006See eligibility →

Opening soonNot applicable

Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis

Obesity, Weight LossCondition

Embospheres MicrospheresTreatment

United States1 locations

Keith Pereira, MD:Sponsor

Updated 2025-07-28 · NCT02933554See eligibility →

Opening soonNot applicable

Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptation, and Nitrogen Balance in Adults Aged 45 Years and Older With Overweight or Obesity Receiving Incretin-based Medications

Obesity, Overweight (BMI > 25)Condition

Whey Protein Supplement, Resistance Training ProgramTreatment

Locations pending0 locations

Assuta Medical CenterSponsor

Updated 2025-04-30 · NCT06950684See eligibility →

Opening soonNot applicable

Does Use of the Voy Program Improve Weight Loss Percentage and Other Health Outcomes in a Population Already Taking GLP/GIP-1RA Medication?

Obesity, Weight LossCondition

Voy ProgramTreatment

Locations pending0 locations

Menwell LimitedSponsor

Updated 2024-11-29 · NCT06710587See eligibility →

Opening soonNot applicable

A New Model of Exercise Referral Scheme Before and After Bariatric Surgery for People With Obesity

Obesity, Quality of LifeCondition

Behavioral to reduce sedentary behvaior, Physical activityTreatment

Locations pending0 locations

Fundació Universitària del BagesSponsor

Updated 2024-08-07 · NCT06541977See eligibility →

Opening soonPhase 4

Efficacy of Henagliflozin for Weight Loss in Obesity Without Diabetes

Obese, Weight LossCondition

Henagliflozin, PlaceboTreatment

Locations pending0 locations

The First People's Hospital of ChangzhouSponsor

Updated 2024-01-22 · NCT06216340See eligibility →

Opening soonNot applicable

The Therapeutic Effect of Different Exercise Intensities on Weight Loss in Obese Children

Weight Loss, Obese Children and AdolescentsCondition

high-intensity interval training, moderate intensity continuous trainingTreatment

Locations pending0 locations

Third Affiliated Hospital, Sun Yat-Sen UniversitySponsor

Updated 2024-01-16 · NCT06205563See eligibility →

Invitation onlyNot applicable

A Prospective Cohort Study on Patient With Obesity Undergoing Weight Change

Obesity & Overweight, Weight LossCondition

Intervention not listedTreatment

Taiwan1 locations

National Taiwan University HospitalSponsor

Updated 2026-03-30 · NCT07239167See eligibility →

Invitation onlyNot applicable

Endoscopic Metabolic and Bariatric Therapies

Obesity, Obesity, MorbidCondition

Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical ProceduresTreatment

United States1 locations

Christopher C. Thompson, MD, MScSponsor

Updated 2025-12-02 · NCT05725967See eligibility →

Invitation onlyNot applicable

Multivitamin Impact on Micronutrient Status in GLP-1 Users: A Randomized Trial

Weight Loss, Nutritional DeficienciesCondition

Multivitamin Supplementation, PlaceboTreatment

Netherlands2 locations

Erasmus Medical CenterSponsor

Updated 2025-11-19 · NCT07234916See eligibility →

Invitation onlyNot applicable

Laparoscopic Gastric Bypass Versus Laparoscopic Banded Gastric Bypass Randomized Prospective Clinical Trial

Morbid Obesity, Weight LossCondition

Banded (with polypropylene mesh) gastric bypass, Gastric bypassTreatment

Spain1 locations

Puerta de Hierro University HospitalSponsor

Updated 2020-04-21 · NCT02939664See eligibility →

Active, not recruitingPhase 2

Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment

Electric Stimulation Therapy, ObesityCondition

Transcranial Direct Current Stimulation (TDCS), Sham/no-stimulationTreatment

United States1 locations

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Sponsor

Updated 2026-09-01 · NCT00739362See eligibility →

Active, not recruitingNot applicable

Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers

Time Restricted Eating, ObesityCondition

Time restricted eating, Calorie RestrictionTreatment

United States1 locations

University of Illinois at ChicagoSponsor

Updated 2026-07-21 · NCT05114798See eligibility →

Active, not recruitingNot applicable

Behavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions

Weight LossCondition

CORE Helpline, Extended HelplineTreatment

United States1 locations

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsSponsor

Updated 2026-07-20 · NCT06463249See eligibility →

This page shows the first 60 studies. Use the full search to filter all matches.

Related conditions

Obesity1,102 Obesity & Overweight220 Overweight205 Overweight and Obesity130 Type 2 Diabetes108 Hypertension107

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.