Condition

Clinical trials for Heart Failure

Active public studies that list Heart Failure as a condition.

21active studies

11recruiting now

13countries represented

838largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowPhase 3

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

Obesity, Heart FailureCondition

NNC0487-0111, PlaceboTreatment

Argentina, Australia838 locations

Novo Nordisk A/SSponsor

Updated 2026-08-18 · NCT07567001See eligibility →

Recruiting nowNot applicable

Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure

Type2diabetes, Heart FailureCondition

Community Champions, Homegrown HeroesTreatment

United States2 locations

Johns Hopkins UniversitySponsor

Updated 2026-07-15 · NCT06364644See eligibility →

Recruiting nowNot applicable

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Obesity and Obesity-related Medical Conditions, DiabetesCondition

Endothelial cell collectionTreatment

United States1 locations

Bettina MittendorferSponsor

Updated 2026-05-07 · NCT07083557See eligibility →

Recruiting nowNot applicable

OBESE-HFpEF: Towards Preventing Obesity Related HFpEF

Heart Failure and Preserved Ejection Fraction, Obesity (Disorder)Condition

Intervention not listedTreatment

Netherlands1 locations

Zuyderland Medisch CentrumSponsor

Updated 2026-04-20 · NCT07539766See eligibility →

Recruiting nowNot applicable

Assessment and Management of Multiple Drug Use in Elderly Chronic Disease Patients

Coronary Artery Disease, Diabete MellitusCondition

Intervention not listedTreatment

China1 locations

Xijing HospitalSponsor

Updated 2025-09-18 · NCT07180368See eligibility →

Recruiting nowNot applicable

Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

Obesity, HyperlipidemiasCondition

Lifestyle counseling and coachingTreatment

United States1 locations

West Virginia School of Osteopathic MedicineSponsor

Updated 2025-07-25 · NCT06049420See eligibility →

Recruiting nowNot applicable

Mobile Applet for Weight Management in Obese Heart Failure Patients

Heart Failure, Overweight and ObesityCondition

Full usage of diet management app group and with the full usage of an intelligent weight scale, Limited usage of diet management app group and with the limited usage of an intelligent weight scaleTreatment

China26 locations

Heart Health Research CenterSponsor

Updated 2025-06-27 · NCT06455878See eligibility →

Recruiting nowNot applicable

EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality

Atrial Fibrillation, Coronary Heart DiseaseCondition

Intervention not listedTreatment

United Kingdom1 locations

Future Genetics LimitedSponsor

Updated 2025-03-10 · NCT03987633See eligibility →

Recruiting nowNot applicable

The Effect of Obesity and Weight Loss in Heart Failure With Reduced Ejection Fraction.

Heart Failure, Heart Failure With Reduced Ejection FractionCondition

Diet interventionTreatment

Jersey, United Kingdom2 locations

University of OxfordSponsor

Updated 2025-02-25 · NCT05942287See eligibility →

Recruiting nowPhase 3

Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes

Cardiovascular Diseases, Heart FailureCondition

Aspirin tablet, SemaglutideTreatment

Denmark2 locations

Steno Diabetes Center CopenhagenSponsor

Updated 2025-01-10 · NCT06082063See eligibility →

Recruiting nowNot applicable

Biomarkers in Patients With Suspected HFpEF

Heart Failure, ObesityCondition

Plasma biomarker levelsTreatment

United Kingdom3 locations

NHS Greater Glasgow and ClydeSponsor

Updated 2024-02-13 · NCT06101693See eligibility →

Opening soonNot applicable

eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF

Heart Failure and Preserved Ejection Fraction, Obesity & OverweightCondition

Digital lifestyle education program, Usual CareTreatment

Spain1 locations

Maimónides Biomedical Research Institute of CórdobaSponsor

Updated 2026-06-22 · NCT07661732See eligibility →

Opening soonNot applicable

CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry

Psoriatic Arthritis, OsteoarthitisCondition

TirzepatideTreatment

Mexico1 locations

JULIO GRANADOS MONTIELSponsor

Updated 2026-05-12 · NCT07567378See eligibility →

Opening soonPhase 3

Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement

Aortic Stenosis, Heart FailureCondition

Wegovy ®, PlaceboTreatment

Locations pending0 locations

Leiden University Medical CenterSponsor

Updated 2025-07-29 · NCT07090343See eligibility →

Invitation onlyNot applicable

Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF

Diabetes (DM), HypertensionCondition

Intervention not listedTreatment

Locations pending0 locations

Chinese Academy of Medical Sciences, Fuwai HospitalSponsor

Updated 2026-01-23 · NCT07336316See eligibility →

Active, not recruitingNot applicable

Screening Adults With Obesity to Reduce Heart Failure Events

Obesity, Heart FailureCondition

Screening for heart failureTreatment

Netherlands1 locations

Franciscus GasthuisSponsor

Updated 2026-09-03 · NCT06137261See eligibility →

Active, not recruitingNot applicable

Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)

Type 2 Diabetes, Heart FailureCondition

Oral semaglutide, SitagliptinTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2026-07-01 · NCT07390110See eligibility →

Active, not recruitingNot applicable

Digital Implementation of the German S3 Clinical Practice Guideline for Multimorbidity

Asthma Bronchiale, Breast NeoplasmsCondition

gp-multitool.deTreatment

Germany1 locations

Universitätsklinikum Hamburg-EppendorfSponsor

Updated 2026-05-29 · NCT06831994See eligibility →

Active, not recruitingNot applicable

Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction

Type 2 Diabetes, Heart FailureCondition

Tirzepatide, SemaglutideTreatment

United States1 locations

Brigham and Women's HospitalSponsor

Updated 2026-05-15 · NCT06980623See eligibility →

Active, not recruitingNot applicable

A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti

Hypertension, DiabetesCondition

Observational StudyTreatment

Haiti1 locations

Weill Medical College of Cornell UniversitySponsor

Updated 2026-02-12 · NCT03892265See eligibility →

Active, not recruitingNot applicable

Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 Drugs

Heart Failure, Diabete Type 2Condition

Tirzepatide (Mounjaro), dapagliflozin, empagliflozin, metforminTreatment

Kazakhstan1 locations

Nazarbayev UniversitySponsor

Updated 2026-01-28 · NCT07303556See eligibility →

Related conditions

Obesity1,102 Obesity & Overweight220 Overweight205 Overweight and Obesity130 Type 2 Diabetes108 Hypertension107

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.