Clinical trial

Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF

Invitation only · Not applicable · 0 countries · Registry ID NCT07336316

Invitation onlyNot applicableObservational

What this study is about

This is an observational study aiming to characterize the pathophysiological features and clinical significance of cardiometabolic early-stage heart failure using advanced multimodal cardiovascular magnetic resonance (CMR) imaging. The study will focus on patients with cardiometabolic risk factors such as diabetes, hypertension, and obesity who are in the pre-heart failure (pre-HF) stage or have heart failure with preserved ejection fraction (HFpEF). The study seeks to establish a full-chain imaging framework-from precise phenotypic classification and sensitive noninvasive diagnosis to individualized cardiovascular risk stratification. Participants will undergo multimodal CMR scans and comprehensive clinical evaluations and be followed up for primary outcome.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

AgeNot listed to Not listed

SexAll

Healthy volunteersAccepted

ConditionDiabetes (DM), Hypertension, Heart Failure, Obesity & Overweight

Full registry criteria

Inclusion Criteria: * Left ventricular ejection fraction (LVEF) ≥ 50%； * Presence of cardiovascular risk factors, including, but not limited to, the following: diabetes mellitus, hypertension, obesity. Exclusion Criteria: * Primary cardiomyopathy (e.g., hypertrophic, dilated, and restrictive cardiomyopathy) * Acute coronary syndrome in the previous 30 days * More than moderate valvular disease * Restrictive pericardial disease * Severe arrhythmia * Heart tumors * Infiltrative cardiomyopathy (e.g., cardiac amyloidosis) * Congenital heart disease * Poor image quality insufficient for delineating the endocardium and epicardium

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Incidence Rate of all cause or cardiovascular death2-15 years

Incidence Rate of HF hospitalization2-15 years

HF hospitalization was defined as an unplanned hospitalization with documented clinical and radiological evidence for HF and need for diuretic treatment

Study locations

0 locations were listed when this page was built. The first 40 are shown.

No public site location was included in this record. Check the original registry for updates.