City

Clinical trials near St Louis, United States

Active studies with a listed research site in St Louis, United States.

29active studies

13recruiting now

8countries represented

46largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowPhase 3

A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities

Obesity, OverweightCondition

Orforglipron, PlaceboTreatment

Israel, Italy34 locations

Eli Lilly and CompanySponsor

Updated 2026-08-24 · NCT06672939See eligibility →

Recruiting nowNot applicable

Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older

Obesity, DepressionCondition

vCare Intervention (6-month active treatment followed by 6-month maintenance), vCare Intervention (active treatment after 6 months)Treatment

United States2 locations

University of Illinois at ChicagoSponsor

Updated 2026-08-18 · NCT06636058See eligibility →

Recruiting nowNot applicable

Role of KATP Channel Loss in Type 2 Diabetes

Obesity and Type 2 DiabetesCondition

10 mg glipizide ingestionTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-08-10 · NCT06830096See eligibility →

Recruiting nowNot applicable

Advancing Biopsychosocial Care Training Initiative

Weight Management, Obesity PreventionCondition

Comprehensive Multidisciplinary Obesity Care, Implementation as Usual ControlTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-08-10 · NCT07049861See eligibility →

Recruiting nowNot applicable

Small Extracellular Vesicles and Insulin Action

Obesity, Insulin ResistanceCondition

People with Metabolically Unhealthy Obesity - Low Calorie DietTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-07-17 · NCT05933707See eligibility →

Recruiting nowNot applicable

Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics

Cardiovascular Diseases, ObesityCondition

Wait-List Control, PREVENT ToolTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-07-17 · NCT06397729See eligibility →

Recruiting nowNot applicable

Adapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics

Obesity, Cardiovascular DiseasesCondition

PREVENT, Wait-list ControlTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-07-16 · NCT06063564See eligibility →

Recruiting nowPhase 2

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, ObesityCondition

bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester), PlaceboTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-07-15 · NCT07097506See eligibility →

Recruiting nowNot applicable

Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity

Obesity, Skeletal MuscleCondition

Exercise training, SemaglutideTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-07-10 · NCT07091500See eligibility →

Recruiting nowPhase 2

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

Crohn Disease (CD)Condition

Tirzepatide, Standard of care treatmentTreatment

United States3 locations

Washington University School of MedicineSponsor

Updated 2026-06-05 · NCT06976853See eligibility →

Recruiting nowNot applicable

Alzheimer"s Imaging Biomarkers in Obesity

Alzheimer Disease, ObesityCondition

Intervention not listedTreatment

United States1 locations

Cyrus A RajiSponsor

Updated 2026-05-11 · NCT05077579See eligibility →

Recruiting nowPhase 2

Uterine Preservation Via Lifestyle Transformation

Endometrial Hyperplasia, Grade 1 Endometrial CancerCondition

Telemedicine behavioral weight intervention, ProgestinTreatment

United States3 locations

Washington University School of MedicineSponsor

Updated 2026-01-20 · NCT05903131See eligibility →

Recruiting nowNot applicable

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

Type2 Diabetes, Type 2 Diabetes Mellitus in ObeseCondition

ObservationalTreatment

United States2 locations

Washington University School of MedicineSponsor

Updated 2025-12-18 · NCT05277558See eligibility →

Opening soonPhase 3

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

Overweight, ObesityCondition

Zenagamtide, SemaglutideTreatment

United States43 locations

Novo Nordisk A/SSponsor

Updated 2026-08-25 · NCT07668414See eligibility →

Opening soonPhase 4

Tirzepatide for Ileal Pouch-anal Anastomosis (IPAA) and Chronic High Bowel Frequency (I8F-NS-X008)

Pouch, Ileal, Pouches, IleoanalCondition

Tirzepatide, LoperamideTreatment

United States5 locations

University of North Carolina, Chapel HillSponsor

Updated 2026-08-10 · NCT07756359See eligibility →

Opening soonPhase 2

Semaglutide for Low Back Pain

Lower Back Pain, Obesity (BMI>30)Condition

Semaglutide (administered by PDS290 pen-injector), Placebo (administered by PDS290 pen-injector)Treatment

United States2 locations

Washington University School of MedicineSponsor

Updated 2026-07-28 · NCT07731256See eligibility →

Opening soonNot applicable

Weight Gain in Pediatric Leukemia Survivors

Leukemia, Pediatric Acute Lymphoblastic LeukemiaCondition

Modified Guided Self-Help Family Intervention, NIH Educational ResourcesTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-07-24 · NCT07374315See eligibility →

Opening soonNot applicable

Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis

Obesity, Weight LossCondition

Embospheres MicrospheresTreatment

United States1 locations

Keith Pereira, MD:Sponsor

Updated 2025-07-28 · NCT02933554See eligibility →

Active, not recruitingNot applicable

The PIVOT Trial: Project on EHR-Integrated Lifestyle Interventions for Adults Aged Fifty and Older

CARDIOMETABOLIC CONDITIONS, ObesityCondition

Base intervention, Augmented InterventionTreatment

United States3 locations

University of Illinois at ChicagoSponsor

Updated 2026-08-31 · NCT05654142See eligibility →

Active, not recruitingNot applicable

Postprandial Nutrient Homeostasis Before and After Weight Loss Induced by Low-calorie Diet or RYGB

ObesityCondition

Roux-en-Y gastric bypass surgery, Low-calorie dietTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-08-25 · NCT03091725See eligibility →

Active, not recruitingNot applicable

NOURISH-T+: Promoting Healthy Eating and Exercise Behaviors

Obesity, Childhood, CancerCondition

NOURISH-T+, Brief NOURISH-T+Treatment

United States10 locations

University of South FloridaSponsor

Updated 2026-08-12 · NCT04656496See eligibility →

Active, not recruitingPhase 3

A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term

ObesityCondition

CagriSema (Cagrilintide B and Semaglutide I), Placebo matched to CagriSema (Cagrilintide B and Semaglutide I)Treatment

United States46 locations

Novo Nordisk A/SSponsor

Updated 2026-07-24 · NCT07011667See eligibility →

Active, not recruitingPhase 2

Efficacy and Safety of Ribupatide (KAI-9531) Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes

ObesityCondition

Ribupatide, PlaceboTreatment

United States35 locations

KaileraSponsor

Updated 2026-07-15 · NCT07458269See eligibility →

Active, not recruitingNot applicable

Precision Nutrition and Metabolic Function

Obesity, Insulin ResistanceCondition

Mediterranean diet, Low-carbohydrate, ketogenic dietTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-07-06 · NCT04131166See eligibility →

Active, not recruitingPhase 3

A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

Obesity, OverweightCondition

Tirzepatide, PlaceboTreatment

Canada, Czechia33 locations

Eli Lilly and CompanySponsor

Updated 2026-06-29 · NCT06075667See eligibility →

Active, not recruitingNot applicable

Study of Fat Tissue's Ability to Take up Sugar in the Obese Population

Glucose Metabolism DisordersCondition

Weight LossTreatment

United States1 locations

University of Missouri-ColumbiaSponsor

Updated 2026-05-08 · NCT02994459See eligibility →

Active, not recruitingNot applicable

Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health

Obesity, Insulin ResistanceCondition

Metabolically abnormal obese - Mediterranean diet, Metabolically abnormal obese - Low carbohydrate ketogenic dietTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2026-01-27 · NCT02706262See eligibility →

Active, not recruitingNot applicable

Role of Immune System in Obesity-related Inflammation and Cardiometabolic Risk

Non-alcoholic Fatty Liver Disease, Metabolic SyndromeCondition

Weight lossTreatment

United States1 locations

Washington University School of MedicineSponsor

Updated 2025-10-23 · NCT01104220See eligibility →

Active, not recruitingNot applicable

The AUDACITY Study (AllUrion Device in Adults With Clinical ObesITY)

ObesityCondition

AGBSTreatment

United States17 locations

Allurion TechnologiesSponsor

Updated 2024-10-26 · NCT05368259See eligibility →

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.

Clinical trials near St Louis, United States

Current studies

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