Clinical trial

This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder

Recruiting now · Not applicable · 1 countries · Registry ID NCT07804680

Recruiting nowNot applicableObservational

What this study is about

The goal of this observational study is to evaluate cardiorespiratory and muscular fitness in children with obesity, with and without autism spectrum disorder (ASD), and examine how fitness relates to body measurements, body composition, and cardiometabolic health. The main questions it aims to answer are: * Do children with and without ASD differ in cardiorespiratory fitness and handgrip strength? * Are fitness levels related to body composition and measures of cardiometabolic health? Researchers will compare children with ASD to children without ASD to see if there are differences in fitness, body composition, and cardiometabolic health. Participants will have information from their medical records reviewed, including: * Cardiorespiratory fitness and handgrip strength test results * Height, weight, BMI, and body composition measurements * Blood test results, including HbA1c and cholesterol levels * Age, sex, and other demographic information

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age6 Years to 18 Years

SexAll

Healthy volunteersNot accepted

ConditionAutism Spectrum Disorder (ASD), Cardiometabolic Health Indicators, Cardiometabolic Risk Factors, Metabolic Syndrome, Prediabetes

Full registry criteria

Inclusion Criteria: * Pediatric patients 6-18 years of age who received care at the Pediatric Endocrinology Diabetes Prevention and Fitness Clinic between January 1 and December 31, 2026. * BMI ≥95th percentile for age and sex, consistent with the definition of pediatric obesity. * Documented results from cardiorespiratory fitness testing and/or handgrip strength testing. * Documented HbA1c value, when available. * Sufficient medical record information to determine ASD status and the primary study outcomes. Exclusion Criteria: * Age \<6 or \>18 years at the time of clinical assessment. * BMI \<95th percentile for age and sex. * Absence of documented cardiorespiratory fitness or handgrip strength testing. * Insufficient medical record information to determine ASD status or primary study outcomes. * Duplicate or unusable medical records.

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Cardiorespiratory FitnessJanuary 1 - December 31 2026

Cardiorespiratory Fitness as determined by 3-minute step test results, which includes post 1-minute heartrate per Kasch Pulse Recovery Test

Handgrip StrengthJanuary 1 - December 31 2026

As defined by handgrip test using hand dynamometer in kilograms

Aerobic CapacityJanuary 1, 2026 to December 31, 2026

Estimation of VO2 max per ml/kg/min derived from results of 3-minute step test

Study locations

1 locations were listed when this page was built. The first 40 are shown.

UVA Health🇺🇸 Charlottesville, Virginia, United States

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Aaron Meadows, MMedContact

Email · Call 434-924-0395

Aaron Meadows, MMedContact

Email · Call 8592004427

Aaron Meadows, MMedPrincipal Investigator