Clinical trial

MRI Assessment of Body Composition in Bariatric Surgery

Invitation only · Not applicable · 1 countries · Registry ID NCT07711925

Invitation onlyNot applicableInterventional

What this study is about

The goal of this observational study is to evaluate changes in adipose tissue and skeletal muscle distribution using magnetic resonance imaging (MRI) in adults with obesity undergoing bariatric surgery. The study also aims to investigate the relationship between MRI-derived body composition parameters and metabolic outcomes following surgical treatment of obesity. The main questions it aims to answer are: How does bariatric surgery affect the distribution of visceral, subcutaneous, hepatic, perirenal adipose tissue and skeletal muscle over 12 months? Are changes in MRI-derived body composition associated with improvements in metabolic parameters after bariatric surgery? Participants will: undergo MRI examinations before bariatric surgery and at 1, 6, and 12 months after surgery; undergo routine clinical and metabolic assessments during standard postoperative follow-up; have MRI-derived body composition measurements correlated with metabolic outcomes over the 12-month follow-up period.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexAll

Healthy volunteersNot accepted

ConditionObesity (BMI>30)

Full registry criteria

Inclusion Criteria: * Age 18 years or older * BMI \>= 30 kg/m2 * qualified to undergo bariatric surgery * Ability to provide written informed consent * Willingness to undergo magnetic resonance imaging before surgery and 3, and 12 months after surgery Exclusion Criteria: * Previous bariatric surgery * Presence of ferromagnetic implants or other contraindications to magnetic resonance imaging * Previous plastic or surgical procedures affecting the body region assessed by MRI, except cholecystectomy, appendectomy, or inguinal hernia repair * Chronic kidney disease stage 4 or higher * Pregnancy * Claustrophobia preventing MRI examination * Inability or unwillingness to provide informed consent

Treatments and study arms

MRI

Diagnostic Test

Magnetic resonance imaging (MRI) will be used to assess body composition before bariatric surgery and at 1, 3, and 12 months after surgery. MRI examinations will quantify visceral and subcutaneous adipose tissue, skeletal muscle volume, intramuscular fat, hepatic fat, and perirenal fat. Imaging findings will be analyzed longitudinally and correlated with routine clinical and metabolic parameters to evaluate changes in body composition following bariatric surgery.

Primary outcomes

Change in abdominal adipose tissue distribution assessed by magnetic resonance imaging (MRI)Baseline and 3 and 12 months after bariatric surgery

Change in visceral and subcutaneous abdominal adipose tissue volume measured by MRI and its association with metabolic outcomes following bariatric surgery.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

University of Warmia and Mazury🇵🇱 Olsztyn, Warminsko-mazusrkie, Poland

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