Clinical trial
Effects of Functional Oils on Obesity With Mild Cognitive Impairment
Opening soon · Not applicable · 1 countries · Registry ID NCT07690384
What this study is about
The purpose of this study is to investigate the effects of diacylglycerol (DAG) oil on obesity accompanied by mild cognitive impairment (MCI). Participants aged 45 to 75 years with obesity and MCI will be randomly assigned to two groups: a control group receiving regular rapeseed oil (RSO) and an experimental group receiving rapeseed-based DAG oil. The dietary intervention will last for 6 months. The main goal is to observe whether this functional oil intervention can improve cognitive function and regulate white adipose tissue browning.
Basic eligibility
Full registry criteria
Treatments and study arms
Rapeseed Oil (RSO)
A commercially available conventional rapeseed oil for daily household cooking use, containing diacylglycerol (DAG) only at the trace level naturally occurring in regular vegetable oil.
Diacylglycerol Oil (DAG Oil)
A rapeseed oil-based functional oil produced via lipase-catalyzed enzymatic conversion, with a diacylglycerol content ≥40% (national standard requirement), for daily household cooking use in place of conventional cooking oil.
Primary outcomes
Change from baseline in cognitive function assessed by the Montreal Cognitive Assessment (MoCA), which evaluates visuospatial/executive function, naming, memory, attention, language, abstraction, delayed recall, and orientation. Total score ranges from 0 to 30, with higher scores indicating better cognitive function.
Change from baseline in body weight (kg) measured by bioelectrical impedance analysis (InBody body composition analyzer).
Change from baseline in body fat percentage measured by bioelectrical impedance analysis (InBody body composition analyzer).
Study locations
1 locations were listed when this page was built. The first 40 are shown.