Clinical trial

Eating Behavior, Nutritional Status and Appetite Hormones After Bariatric Surgery

Opening soon · Not applicable · 1 countries · Registry ID NCT07636239

Opening soonNot applicableObservational

What this study is about

This study aims to evaluate changes in eating behavior attitudes, nutritional status, and appetite-regulating hormonal parameters in individuals who have undergone Laparoscopic Sleeve Gastrectomy (LSG). The study will be conducted at Bursa Yıldırım Doruk Hospital, Department of General Surgery. A total of 40 volunteer participants who underwent LSG within the last month will be included. Participants will be assessed at baseline (shortly after surgery) and at 6-month follow-up. Assessments will include anthropometric measurements (body weight, height, waist and hip circumference, BMI, waist-to-hip ratio), 3-day dietary intake records analyzed using BeBIS 8.2 software, and the Adult Eating Behavior Scale. Biochemical parameters including fasting blood glucose, total cholesterol, triglycerides, HDL, LDL, VLDL cholesterol, and insulin will be obtained from patient files and analyzed using Advia Chemistry 2400 and Advia XPT devices. Additionally, appetite-regulating hormones (ghrelin, GLP-1, PYY) will be analyzed from residual blood samples using the ELISA method with RelAssay Diagnostics kits by Teknogen Bioengineering Laboratory. All data will be compared between baseline and 6-month follow-up to evaluate the impact of bariatric surgery on nutritional and hormonal outcomes.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 50 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity, Bariatric Surgery, Laparoscopic Sleeve Gastrectomy, Eating Behavior, Nutritional Status

Full registry criteria

Inclusion Criteria: * Having undergone Laparoscopic Sleeve Gastrectomy (LSG) within the last month * Aged between 18-50 years * Signing the informed consent form * Having a Body Mass Index (BMI) of 40 kg/m2 or between 35-40 kg/m2 with obesity-related comorbidities * No diagnosis of depression * No eating behavior disorder * No psychiatric disorder Exclusion Criteria: * Not having undergone Laparoscopic Sleeve Gastrectomy (LSG) or not planning to undergo bariatric surgery * Not being in the age range of 18-50 years * Not signing the informed consent form * Having a Body Mass Index (BMI) greater than 40 kg/m2 or less than 35 kg/m2 without obesity-related comorbidities * Having a diagnosis of depression * Having an eating behavior disorder * Having a psychiatric disorder

Treatments and study arms

Anthropometric Measurements and Dietary Assessment

Other

Anthropometric measurements (body weight, height, waist and hip circumference, BMI, waist-to-hip ratio), 3-day dietary intake records, Adult Eating Behavior Scale, and biochemical and hormonal parameters (fasting blood glucose, lipid profile, insulin, ghrelin, GLP-1, PYY) will be assessed at baseline and at 6-month follow-up.

Primary outcomes

Change in Serum Ghrelin Concentration (pg/mL)Baseline and 6 months after surgery

Change in serum ghrelin levels between baseline and 6-month follow-up, assessed by ELISA method.

Change in Serum GLP-1 Concentration (pmol/L)Baseline and 6 months after surgery

Change in serum glucagon-like peptide-1 (GLP-1) levels between baseline and 6-month follow-up, assessed by ELISA method.

Change in Serum PYY Concentration (pg/mL)Baseline and 6 months after surgery

Change in serum peptide YY (PYY) levels between baseline and 6-month follow-up, assessed by ELISA method.

Change in Adult Eating Behavior Scale Total Score (0-100)Baseline and 6 months after surgery

Change in Adult Eating Behavior Scale total score between baseline and 6-month follow-up. Scale is scored between 0-100; higher scores indicate more positive eating behavior attitudes.

Change in Daily Energy Intake (kcal/day)Baseline and 6 months after surgery

Change in daily energy intake assessed by 3-day dietary intake records at baseline and 6-month follow-up. Food portions will be estimated using the Food and Nutrient Photo Catalog. Data will be analyzed using BeBIS 8.2 software and evaluated according to Turkish Dietary Guidelines 2022.

Change in Daily Protein Intake (g/day)Baseline and 6 months after surgery

Change in daily protein intake assessed by 3-day dietary intake records at baseline and 6-month follow-up. Food portions will be estimated using the Food and Nutrient Photo Catalog. Data will be analyzed using BeBIS 8.2 software and evaluated according to Turkish Dietary Guidelines 2022

Change in Daily Carbohydrate Intake (g/day)Baseline and 6 months after surgery

Change in daily carbohydrate intake assessed by 3-day dietary intake records at baseline and 6-month follow-up. Food portions will be estimated using the Food and Nutrient Photo Catalog. Data will be analyzed using BeBIS 8.2 software and evaluated according to Turkish Dietary Guidelines 2022.

Change in Daily Fat Intake (g/day)Baseline and 6 months after surgery

Change in daily fat intake assessed by 3-day dietary intake records at baseline and 6-month follow-up. Food portions will be estimated using the Food and Nutrient Photo Catalog. Data will be analyzed using BeBIS 8.2 software and evaluated according to Turkish Dietary Guidelines 2022.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Bursa Yıldırım Doruk Hastanesi, General Surgery Clinic🌐 Bursa, Bursa, Turkey (Türkiye)

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Özlem ÖZPAK AKKUŞ, Assoc. Prof.Contact

Email · Call +903246253300

Doğukan DURAK, Assoc. Prof.Contact

Email · Call +905327243733

Özlem ÖZPAK AKKUŞ, Assoc. Prof.Principal Investigator