Clinical trial

Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults

Recruiting now · Not applicable · 1 countries · Registry ID NCT07582718

Recruiting nowNot applicableInterventional

What this study is about

This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity. WB-HIIT is a practical and time-efficient training modality based on body-weight exercises performed at high intensity with short recovery intervals. It may offer an accessible approach for improving health in individuals with excess body weight. Participants aged 18 to 55 years with a body mass index (BMI) between 25 and 35 kg/m² will take part in a supervised 10-week WB-HIIT program, performed in small groups and led by trained exercise professionals. Before and after the intervention, participants will undergo assessments including DXA-based body composition analysis, fasting blood sampling, muscular strength testing, a Chester step test, a maximal graded treadmill exercise test with gas-exchange analysis to determine VO₂peak, and functional evaluations (chair-stand, arm-curl, and 6-minute walk test). Physical activity and dietary intake will also be recorded. The primary objective of the study is to assess whether WB-HIIT improves cardiorespiratory fitness (VO₂peak) in adults with overweight. Secondary objectives include evaluating changes in muscular strength, body composition, metabolic markers, and functional capacity. The results may help determine whether an equipment-free WB-HIIT program can serve as an effective and accessible training approach for improving health and physical fitness in adults with overweight and obesity.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 55 Years

SexAll

Healthy volunteersNot accepted

ConditionOverweight and/or Obesity

Full registry criteria

Inclusion Criteria: * Adults aged 18 to 55 years. * Body mass index (BMI) between 25 and 35 kg/m². * Able to provide written informed consent. * Able to safely participate in high-intensity interval training. * For participants with BMI \> 30 kg/m²: medical clearance from their general practitioner. Exclusion Criteria: * BMI \< 25 or \> 35 kg/m². * Presence of any chronic medical condition other than overweight/obesity. * Known cardiovascular, metabolic, respiratory, or musculoskeletal disease that contraindicates high-intensity exercise. * Pregnancy. * Inability to perform exercise testing or complete the WB-HIIT program. * Any condition judged by investigators to interfere with participation or data interpretation.

Treatments and study arms

Whole-Body High-Intensity Interval Training (WB-HIIT)

Behavioral

A structured WB-HIIT program using body-weight exercises such as squats, lunges, mountain climbers, and similar multi-joint movements. Sessions last 35-50 minutes and include 3 to 4 sets of interval blocks performed at high intensity. The training is supervised by qualified exercise professionals.

Primary outcomes

Peak oxygen consumption (VO₂peak)The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.

Peak oxygen consumption (VO₂peak) will be measured during a maximal graded treadmill exercise test with gas analysis to assess changes in cardiorespiratory fitness following the 10-week WB-HIIT program. VO₂peak will be expressed in mL·kg-¹·min-¹.

Muscular strengthThe outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.

Maximal dynamic strength will be assessed using 3-repetition maximum (3-RM) tests on the leg press and bench press.

Study locations

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Université libre de Bruxelles (ULB)🇧🇪 Brussels, Belgium

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