Clinical trial

IMPACT: Immune and Musculoskeletal Physiological Adaptations to Combined Exercise Training & Nutrition

Opening soon · Not applicable · 1 countries · Registry ID NCT07513987

Opening soonNot applicableInterventional

What this study is about

The purpose of this study is to determine whether 12 weeks of exercise training combined with dairy consumption influences inflammation and immune responses in adults with overweight, compared to exercise training alone.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 50 Years

SexAll

Healthy volunteersAccepted

ConditionOverweight (BMI > 25), Males and Females

Full registry criteria

Inclusion Criteria: * Between the ages of 18 and 50 years * Overweight BMI (25.0-29.9) kg/m2 * 'Overweight' body fat percentage (males: ≤30%; females: ≤42%) * Low to moderately physically active (0-2 times/week) * Habitual low dairy consumption (≤ 1 serving/day, assessed via baseline food record) Exclusion Criteria: * Peri- or postmenopausal status (female) * Dairy protein allergy or lactose intolerance * Use of vitamin D and/or calcium supplements * Any musculoskeletal, autoimmune, or inflammatory conditions * Use of medication related to a chronic condition

Treatments and study arms

Milk

Dietary Supplement

2 servings of 1% MF milk (1 serving = 250 mL) on non-training days and 3 servings on training days, integrated into habitual diet.

Greek Yogurt

Dietary Supplement

2 servings of plain or flavoured GY (1 serving = 175 g) on non-training days, and 3 servings of GY on training days, integrated into your habitual diet.

Exercise training

Behavioral

12-week structured exercise training program. Exercise sessions will take place three times per week and will last approximately 60 minutes per session. Sessions will be conducted at York University in the Exercise Research Lab. Each session will be facilitated by a certified personal trainer and/or kinesiology student

Primary outcomes

Inflammatory Cytokines assessed from blood samples via Elisaweek 0 and week 12

e.g., Interleukin-6 (IL-6)

Body Composition determined via Bodpodweek 0 and week 12

e.g., Lean mass

Bone turnover assessed from blood samples via Elisaweek 0 and week 12

e.g., Procollagen type 1 N-propeptide (P1NP)

Study locations

1 locations were listed when this page was built. The first 40 are shown.

York University🇨🇦 Toronto, Ontario, Canada

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