Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock

Inclusion Criteria * Adults aged 40-89 years, who are newly enrolled in the NOVI OP+ weight management program. * BMI of ≥ 30 kg/m2 (obesity); OR * BMI of ≥ 27 kg/m2 to \< 30 kg/m2 (overweight) in the presence of at least one weight-related comorbid condition e.g. dysglycemia (prediabetes or type 2 diabetes mellitus), hypertension, dyslipidemia, obstructive sleep apnea or cardiovascular disease. Exclusion Criteria * Pregnancy or lactation. * Non-ambulatory status, total blindness, complete hearing loss, or inability to speak. * Medical history of, or self-reported, psychiatric illness, congenital or irreversible neurodegenerative diseases, cognitive impairment, or eating disorders that may affect adherence or assessment outcomes. * On GLP-1 RA, sulfonylurea or insulin medications for the past 3 months. * Active cancer on chemotherapy or immunotherapy. * Known hypersensitivity or contraindications to GLP-1 RAs. * Any condition, in the opinion of the attending clinician, that would jeopardize participant safety or interfere with study compliance.