Clinical trial

Effects of Exercise on Lipids and Endothelial Function in Youth

Recruiting now · Not applicable · 1 countries · Registry ID NCT07409064

Recruiting nowNot applicableInterventional

What this study is about

This study is for individuals who have a BMI that is at or above the 95th percentile and are participating in the Cincinnati Children's Hospital Healthworks! Structured weight loss program. The main reason for this research study is to determine how exercise affects an individual's high level of lipids (fats) in their blood and how well their blood vessels function.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age10 Years to 20 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity & Overweight

Full registry criteria

Inclusion Criteria: 1. Age: 10-20 years 2. Obesity as defined by BMI ≥ 30 kg/m2 OR BMI ≥ 95%ile for age and sex 3. Planned to start the Healthworks! structured weight loss program. 4. English or Spanish speaking - Exclusion Criteria: 1\. Physician judgement about inability to finish the protocol \-

Treatments and study arms

Exercise Program

Other

Single arm study to evaluate the effectiveness of standard of care exercise program intervention. Effectiveness to be measured with a Garmin Vivosmart Fitness watch, endothelial function testing, carotenoid testing, and standard of care triglyceride level blood draw.

Primary outcomes

Difference in Percent Change in Perfusion Units from Baseline to 6 months6 months

To determine if increased levels of physical activity are associated with percent change in perfusion units utilizing laser flow doppler measurement at baseline and again after 6 months of a structured physical activity and weight loss program.

Increase in Physical Activity will Lead to Change in Triglyceride Levels6 months

To determine if higher levels of physical activity are associated with greater decreases in blood triglyceride levels in youth with obesity and hyperlipidemia undergoing a structured weight loss program.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Cincinnati Children's Hospital Medical Center🇺🇸 Cincinnati, Ohio, United States

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Jordan Sill, MDContact

Email · Call 513-636-4200

Jordan Sill, MDPrincipal Investigator