Clinical trial

Effects of Short Isokinetic Eccentric Resistance Training on Neuromuscular Induced Adaptations

Invitation only · Not applicable · 1 countries · Registry ID NCT07407621

Invitation onlyNot applicableInterventional

What this study is about

The study compares the impact of isokinetic resistance training (RT) -induced neuromuscular adaptation following an 8-week short ECC ISO RT and CON ISO RT among obese, untrained women. The main question it aims to answer is: 1\. Does exercise-induced neuromuscular adaptation following progressive short ECC ISO RT, more effectively than CON ISO RT, among obese, untrained women? Researchers will compare drug ECCISO RT to a CONISO RT to see if ECCISO RT is more effective in inducing neuro-muscular adaptations in obese, untrained women. Participants will: 1. Train on isokinetic ECC or CON for 8 weeks 2. Visit the clinic twice for baseline and post tests

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 45 Years
SexFemale
Healthy volunteersAccepted
ConditionObesity, Physical Inactivity

Full registry criteria

INCLUSION CRITERIA: * Eumenorrheic women (reporting menstrual cycle between 21-35 days) * Age 25-45 y/o * BMI \> 23.0 kg/m2 * Body fat percentage \> 30% * No lower limb orthopaedic injuries * Have not participated in any structured/ unstructured weight loss intervention in the past 12 months * Sedentary lifestyle (regular exercise \<1 hour per week) * Stable body weight (loss or gain of no greater than 2 kg) * Stable medication use for six months before enrolment EXCLUSION CRITERIA: * smokers * taking supplements or medication known to affect REE (such as oral contraceptives) * severe medical conditions affecting their physical or mental health * individuals with an implanted medical device * suffer from alcohol or drug abuse * trying to conceive/ pregnant, or breastfeeding

Treatments and study arms

ECC ISO

Other

Eccentric Isokinetic Exercise

CON ISO

Other

Concentric Isokinetic Exercise

Primary outcomes

Maximal voluntary strength8 weeks

Changes in maximal voluntary strength

Neural activation assessment8 weeks

Changes in neural activation during strength

Fasting plasma glucose8 weeks

Changes in fasting plasma glucose

Functional physical fitness (6-minute walking test)8 weeks

Changes in distance during 6-minute walking test

Indirect calorimetry8 weeks

Changes in basal metobolic rate/ fat oxidation rate/ charbohydrate oxidation rate

HDL cholesterol8-weeks

Changes in HDL cholesterol

LDL cholesterol8-weeks

Changes in LDL cholesterol

Total cholesterol8-weeks

Changes in total cholesterol

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Department of Community Health🇲🇾 Kepala Batas, Pulau Pinang, Malaysia