Clinical trial

Comparison of Genotype-Based Dietary Counseling Versus Standard Dietary Counseling on Weight Loss and Fat Mass Reduction

Recruiting now · Not applicable · 1 countries · Registry ID NCT07368777

Recruiting nowNot applicableInterventional

What this study is about

This study aims to compare the effects of genotype-based dietary counseling with standard dietary counseling based on general recommendations on weight loss and reduction of body fat. Participants will receive individualized dietary guidance either informed by genetic information or based on conventional dietary guidelines. Changes in body weight and body composition will be assessed over the course of the intervention.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 65 Years
SexAll
Healthy volunteersAccepted
ConditionOverweight, Overweight and Obesity, Adiposity

Full registry criteria

Inclusion Criteria: * Adults aged ≥18 years * Body mass index (BMI) ≥25 kg/m² * Greek-speaking (able to read and understand Greek and provide informed consent) * Willing and able to participate in dietary counseling and study assessments for the duration of the study Exclusion Criteria: * Current use of pharmacological treatments for weight loss, including but not limited to GLP-1 receptor agonists, appetite suppressants, or other anti-obesity medications * Participation in any structured weight-loss intervention or program within the previous 3 months, including commercial weight-loss programs or medically supervised dietary interventions * Use of medications known to significantly affect body weight or body composition, such as systemic corticosteroids, antipsychotic medications, or medications for thyroid disorders * Pregnancy or lactation * Presence of medical conditions that may affect body weight, metabolism, or nutritional status, including untreated thyroid disease, severe gastrointestinal disorders, or endocrine disorders

Treatments and study arms

Genotype-Based Dietary Counseling

Behavioral

This intervention consists of dietary counseling informed by individual genetic information. Nutrition guidance is provided by qualified nutrition professionals and aims to support weight management and reduction of body fat over the intervention period.

Standard Dietary Counseling

Behavioral

This intervention consists of dietary counseling based on general dietary guidelines and standard nutrition recommendations. Counseling is delivered by qualified nutrition professionals without the use of genetic information.

Primary outcomes

Change in Fat Mass (%)baseline to end of intervention (12 months)

Change in whole-body fat mass percentage from baseline to end of the intervention

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Dietetics Department, School of Health Sciences, Metropolitan College🇬🇷 Marousi, Greece
Angeliki Kapellou, PhDContact