Clinical trial

Physical Acvitiy in Pregnancy

Invitation only · Not applicable · 1 countries · Registry ID NCT07356180

Invitation onlyNot applicableObservational

What this study is about

The goal of this observational study is to learn how a physically active lifestyle during pregnancy affects placental development and function. The main question it aims to answer is: Does regular physical activity during pregnancy improve placental function and support healthy fetal growth? Pregnant participants will provide biological samples and health information during pregnancy and at delivery. The study will use these samples to examine how activity levels relate to placental energy production and overall health.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 45 Years

SexFemale

Healthy volunteersNot accepted

ConditionPregnant Women, Gestational Diabetes, Obese But Otherwise Healthy Participants, Overweight (BMI > 25), Gestational Diabetes Mellitus in Pregnancy

Full registry criteria

Inclusion Criteria: * Pregnant female and their newborn infant(s) * Aged 18-45 (pregnant female), age 0-60 days of life (newborn infant) * English speaking * Screened for gestational diabetes with standard glucose tolerance test between 24w - 41w gestation * Delivered at gestational age 34week-41weeks * Delivered via non-emergent Cesarean section during weekday hours * No known infectious disease (ex: HIV, HepC) Exclusion Criteria: * Women \<18yo or \>45yo * Non-English speaking * Pre-existing diabetes or diagnosed with diabetes prior to 24weeks * Required complex diets/supplements not related to the pregnancy (i.e. malnutrition) * Known severe fetal anomalies or genetic disorder * Placenta accreta spectrum * Emergent cesarean delivery performed due to fetal distress * Known infectious disease (ex: HIV, HepC)

Treatments and study arms

Pregnancy Physical Activity Questionnaire (PPAQ)

Behavioral

The PPAQ is a semiquantitative questionnaire that asks respondents to report the time spent participating in 32 activities including household/caregiving (13 activities),occupational (5 activities), sports/exercise (8 activities), transportation (3 activities), and inactivity (3 activities). For each activity, respondents are asked to select the category that best approximates the amount of time spent in that activity per day or week during the currenttrimester. Possible durations range from 0 to 6 or more hours per day and from 0 to 3 or more hours per week.

Primary outcomes

Placental mitochondrial functionAt delivery

Placental mitochondrial function will be assessed using markers of mitochondrial biogenesis and energy metabolism measured in placental tissue collected at delivery. Outcomes will be examined in relation to maternal physical activity levels during pregnancy.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

University of Maryland Medical System🇺🇸 Baltimore, Maryland, United States

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