Clinical trial

One-Year Outcomes After Conversion Bariatric Surgery

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT07345429

Active, not recruitingNot applicableObservational

What this study is about

Obesity is a growing global public health problem, and bariatric surgery is currently the most effective treatment for achieving sustained weight loss and improving obesity-related comorbidities. However, a subset of patients experience inadequate weight loss or weight regain following primary bariatric surgery, which may lead to the recurrence of metabolic complications and reduced quality of life. In such cases, conversion bariatric surgery, defined as the surgical conversion from one bariatric procedure to another, is considered an important therapeutic option. Despite the increasing number of conversion procedures, comprehensive longitudinal data evaluating anthropometric, biochemical, and nutritional outcomes after conversion bariatric surgery remain limited. This study aims to prospectively evaluate individuals undergoing conversion bariatric surgery due to weight regain following primary bariatric surgery. Anthropometric measurements, biochemical parameters, and nutritional status will be assessed preoperatively and at 1 year after surgery. By evaluating weight loss outcomes together with metabolic and nutritional changes, this study seeks to provide clinically relevant evidence to guide postoperative follow-up strategies, optimize nutritional management, and support multidisciplinary care in patients undergoing conversion bariatric surgery.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 65 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity & Overweight, Bariatric Surgery, Revisional Bariatric Surgery

Full registry criteria

Inclusion Criteria: * Adults aged 18-45 years * Previously underwent bariatric surgery * Subsequently underwent conversion bariatric surgery due to suboptimal clinical response Suboptimal clinical response defined as either: * Suboptimal Clinical Response (SCR): maximum total weight loss (TWL%) of \<20% within 18 months after metabolic and bariatric surgery * Recurrent Weight Gain (RWG): regaining \>30% of initial postoperative weight loss after achieving initial weight reduction Exclusion Criteria: * Pregnancy or lactation * Presence of acute illness or infection * Comorbid conditions that could limit treatment efficacy or compromise safety * Participation in professional athletic activity

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Change in Body Composition ParametersPreoperative baseline and postoperative 1 year

Body composition parameters including fat mass, fat percentage, fat-free mass, fat-free mass percentage, skeletal muscle mass, muscle percentage, and extracellular water to total body water ratio assessed using multi-frequency bioelectrical impedance analysis (BIA).

Change in Body WeightPreoperative baseline and postoperative 1 year

Change in body weight (kg) measured using a digital scale with participants wearing light clothing and no shoes.

Change in Body Mass Index (BMI)Preoperative baseline and postoperative 1 year

Change in body mass index (kg/m²) calculated from measured body weight and height.

Percentage of Total Weight Losspostoperative 1 year

Percentage of total weight loss calculated as \[(preoperative weight - postoperative weight) / preoperative weight\] × 100.

Percentage of Excess Weight Losspostoperative 1 year

Percentage of excess weight loss calculated as \[(preoperative weight - postoperative weight) / (preoperative weight - ideal body weight)\] × 100, with ideal body weight defined as a BMI of 25 kg/m².

Change in Waist CircumferencePreoperative baseline and postoperative 1 year

Waist circumference (cm) measured in the standing position using a non-elastic measuring tape at the midpoint between the lowest rib and the iliac crest.

Change in Hip CircumferencePreoperative baseline and postoperative 1 year

Hip circumference (cm) measured in the standing position at the point of maximum protrusion of the gluteal muscles using a non-elastic measuring tape.

Change in Body Fat Percentage (%)Preoperative baseline and postoperative 1 year

Body fat percentage measured using multi-frequency bioelectrical impedance analysis (BIA).

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Mudanya Univesity🌐 Osmangazi, Bursa, Turkey (Türkiye)

Open map