Clinical trial

Effect of High-intensity Interval Training on Cardiometabolic Health and Physical Fitness in Young Adults With Obesity

Invitation only · Not applicable · 1 countries · Registry ID NCT07283406

Invitation onlyNot applicableInterventional

What this study is about

The objective of the present project is to compare the effects of two types of training on cardiovascular health components and physical fitness in young adults with obesity.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 35 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity & Overweight

Full registry criteria

Inclusion Criteria: * Young adults * BMI ≥ 30 kg/m\^2" and \< 40 kg/m\^2 * Signed informed consent form Exclusion Criteria: * Participants who smoke * Clinical diagnosis of hypothyroidism * Clinical diagnosis of type 1 diabetes mellitus * Clinical diagnosis of type 2 diabetes mellitus * Clinical diagnosis of grade 3 obesity * Clinical diagnosis of hypertension * Clinical diagnosis of acute myocardial infarction or angina pectoris * Use of nitrates and calcium channel blockers within 4 days prior to the start of the study * Use of beta-blockers or hypoglycemic agents within 7 days prior to the intervention * Pregnant women * Breastfeeding women * Men consuming more than 40 g of alcohol per day or women consuming more than 20 g per day * Postural and biomechanical disorders (knee, foot, and spine)

Treatments and study arms

High-intensity interval training intervention

Other

The HIIT group will undergo training for 12 weeks, with a frequency of three sessions per week, completing a total of 36 sessions. Each session will include a 5-minute warm-up and a 5-minute cool-down at 50-60% of maximum heart rate (HRmax). The training protocol will consist of 2-minute high-intensity intervals performed at 90-95% HRmax, corresponding to a Borg rating of perceived exertion (RPE) of 17-18, alternated with 2-minute recovery periods at 70% HRmax (RPE 12-14). A total of five intervals will be completed per session, resulting in an overall high-intensity workload of 18 minutes. All training sessions will be conducted on a stationary cycle ergometer

Moderate-intensity continuous training intervention

Other

The MICT group will perform moderate-intensity continuous training at 60-70% HRmax, corresponding to an RPE of 12-14, for 35-45 minutes on a stationary cycleergometer. Heart rate and physical activity levels will be continuously monitored in both groups using a chest-strap heart rate sensor (Polar H9, Polar Electro, Finland).

Educational sessions

Other

In addition, four educational sessions will be conducted to provide dietary recommendations to all participants. These sessions will aim to promote balanced eating habits and to discourage the excessive consumption of ultra-processed foods or alcohol, as these factors could interfere with the intervention outcomes.

Primary outcomes

Maximum oxygen uptake (VO₂max)Baseline and after 12 weeks

VO₂max (ml/min/kg): Change from Baseline at 12 weeks, measured using a submaximal exercise test based on the Åstrand-Ryhming protocol

WeightBaseline and after 12 weeks

Weight (kg): Changes in weight from baseline to 12 weeks of intervention.

HeightBaseline and after 12 weeks

Height (cm): Changes in height from baseline to 12 weeks of intervention.

Body mass index (BMI)Baseline and after 12 weeks

BMI (kg/m2): Change from Baseline at 12 weeks, calculated by: weight (kg)/ height (m\^2)

Body fat percentageBaseline and after 12 weeks

Body fat percentage (%): Changes in body fat assessed by bioelectrical impedance analysis (BIA)

Muscle mass percentageBaseline and after 12 weeks

Muscle mass percentage (%): Changes in muscle mass measured using bioelectrical impedance analysis (BIA)

Waist circumferenceBaseline and after 12 weeks

Waist circumference (cm): Changes in waist circumference will be measured using a Lufkin measuring tape (USA) following the guidelines of the International Society for the Advancement of Kinanthropometry (ISAK)

Waist-to-hip ratioBaseline and after 12 weeks

Waist-to-hip ratio: Changes in waist-to-hip ratio will be calculated by dividing the waist measurement by the hip measurement

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Centro Universitario de Tlajomulco, Universidad de Guadalajara🇲🇽 Guadalajara, Jalisco, Mexico

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