Clinical trial

Ketodex Versus Opioid Based Anesthesia in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT07246447

Active, not recruitingNot applicableInterventional

What this study is about

comparing Opioid sparing anesthesia using ketodex versus opioid based anesthesia in obese patients undergoing laparoscopic sleeve gastrectomy.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexAll

Healthy volunteersAccepted

ConditionMorbid Obesity

Full registry criteria

Inclusion Criteria: * Adult patients (\>18 years) undergoing Elective Bariatric Surgery . * American Society of Anesthesiologists physical status class II or III . * body mass index (BMI) \> 35 kg/m2 . Exclusion Criteria: * • Refusal to participate . * Any sensitivity or contraindication to ketamine or dexmedotomidine . * Pregnancy or breast feeding . * Patients with significant renal impairment . * Any patient on regular intake of beta blockers or calcium channel blockers . * CNS disorders eg: seizures , raised intra cranial tension . * Chronic opioid use. * Obese patients with STOP bang score more than 5 .

Treatments and study arms

ketamine and dexmeditomidine combination

Drug

Group KD: Two syringes containing ketodex-ketamine (1 mg/kg) and dexmedetomidine (1 µg/kg)-each diluted with 0.9% saline and infused over 10 minutes. Maintenance will consist of continuous low-dose infusion of ketamine (0.3 mg/kg/h) and dexmedetomidine (0.5 µg/kg/h) in separate syringes until 15 minutes before the end of surgery.

Fentanyl (IV)

Drug

Group OP: Two syringes-one containing fentanyl (2 µg/kg) and the other 0.9% saline-infused over 10 minutes. Maintenance will be provided by two continuous saline infusions, prepared to mimic the ketodex infusions, until 15 minutes before the end of surgery.

Primary outcomes

Total nalbuphine consumption (mg) during the first 24 hours postoperatively.during the first 24 hours postoperatively

Total nalbuphine consumption (mg) during the first 24 hours postoperatively.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Cairo university hospitals🇪🇬 Cairo, Manial, Egypt

Open map