Clinical trial

Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults

Opening soon · Not applicable · 1 countries · Registry ID NCT07229963

Opening soonNot applicableInterventional

What this study is about

The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk markers for cardiometabolic diseases; and (2) to assess substrate oxidation during this period in order to identify which exercise condition promotes the greatest increase in fat oxidation.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age35 Years to 45 Years

SexAll

Healthy volunteersAccepted

ConditionCardiovascular Risk Markers, Substrate Oxidation, Postprandial Metabolism, Exercise Physiology

Full registry criteria

Inclusion Criteria * Being physically inactive (not doing at least 150 minutes/week of structured exercise). * Having a physical activity level of \<5000 steps/day. * Having a BMI between 25 and 29.9 kg/m2. * Having a history of regular menstrual cycles for female participants. * Having medical examination approval. Exclusion Criteria * Taking any acute or chronic medication or supplement that may affect metabolism. * Having an acute or chronic illness that limits exercise (musculoskeletal problems, cardiovascular disorders, respiratory problems, etc.). * Consuming tobacco products. * Meeting 3 or more of the metabolic syndrome criteria (waist circumference of 102 cm or more in men, 88 cm or more in women, triglyceride level of 150 mg/dL or higher, HDL cholesterol level below 40 mg/dL in men and 50 mg/dL in women, blood pressure of 130/85 mmHg or higher, fasting blood glucose level of 100 mg/dL (5.6 mg/L) or higher).

Treatments and study arms

Aerobic Exercise Intervention

Other

In the aerobic exercise condition, participants will perform 2 minutes of moderate-intensity continuous cycling.

Sprint Exercise Intervention

Other

In the sprint condition, participants will complete a 10-second all-out sprint, as determined during the preliminary test.

Sedentary Behaviour Intervention

Other

Participants will remain seated for a total duration of 7 hours. During this period, they will be instructed to minimize excessive movement and will only be permitted to rise from the chair for voiding purposes.

Primary outcomes

Insulin7 hour for each experimental condition

Postprandial insulin. Net incremental area under the curve and total area under the curve for each 7 h condition will be calculated for insulin.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Hacettepe Sports Science Faculty, Hacettepe Beytepe Clinic🌐 Ankara, Beytepe, Turkey (Türkiye)

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Şükran Nazan Koşar, ProfessorContact

Email · Call 0538 861 29 24

Hikmet Sercan ToprakoğluPrincipal Investigator

Seda Hanife Oğuz Baykal, Associate ProfessorSub Investigator