Clinical trial

A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents

Recruiting now · Not applicable · 1 countries · Registry ID NCT07223151

Recruiting nowNot applicableInterventional

What this study is about

The goal of this clinical trial is to test whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health in Black/African American and Latine adolescents with obesity who prefer sweet-tasting beverages. The main questions it aims to answer are: * Does replacing sugary sodas with water change liking for sugary drinks, and water? * Do shifts in liking for sweetness lead to improved diet quality and cardiometabolic health? Researchers will compare replacing sugary sodas with one of three alternative beverages: unsweetened sparkling water, plain water, and beverages with gradually reduced sugar to determine which strategy is most effective. Participants will: * Replace sugary sodas with study drinks for 4 weeks * Complete taste tests to measure their liking for and sensory experience of sweetness over 8-weeks * Provide dietary recalls, body measurements, and blood samples over 8-weeks

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age12 Years to 18 Years
SexAll
Healthy volunteersAccepted
ConditionObesity, Adolescent, Dietary Sugars, Taste Perception, Insulin Resistance, Feeding Behavior

Full registry criteria

Inclusion Criteria: * Adolescents ages 12 to 18 who display a "sweet-liker" pattern, characterized by a preference for higher concentrations of sugar in beverages, specifically identifying 0.3M (10.3% sucrose) or above as their most liked sample. * Adolescents consumes sugar-sweetened soda greater than or equal to 2 times per week. Adolescents must also indicate a willingness to drink study beverages; not currently dieting/changing diet. Exclusion Criteria: * Adolescent participant is pregnant, since pregnancy affects taste perception * Participant is allergic or intolerant to the items we are testing. * Adolescent with type 1 or type 2 diabetes (self-declared or detected at screening visit through fasting glucose) * Use of GLP-1 receptor agonists intended for weight loss.

Treatments and study arms

Unsweetened Sparkling Water Replacement

Behavioral

Participants replace all sugar-sweetened sodas with flavored, unsweetened sparkling waters for 4 weeks.

Progressively Reduced Sugar Beverage Replacement

Behavioral

Participants replace sugary sodas with beverages containing gradually decreasing sugar concentrations (weekly), ending with unsweetened sparkling water.

Plain Water Replacement

Behavioral

Participants replace all sugar-sweetened sodas with plain, still water for 4 weeks. This serves as a comparator to evaluate sensory and metabolic changes.

Primary outcomes

Liking ratings changes for sugar concentrations over timeBaseline, Week 2, Week 4, Week 8

Our primary outcome is the interaction of time with liking for different sugar concentrations. We expect to observe a significant Time\*Sugar Concentration interaction effect for these liking ratings. We expect the interaction term to show that higher concentrations of sugar had lower liking ratings by weeks 4 and 8 (compared to baseline), but that lower concentrations of sugar had higher liking ratings by weeks 4 and 8. Liking ratings are collected on a scale from -110 to 110, with internal markings at -100 Worst ever, -50 Dislike, 0 Neutral, 50 Like, 100 Best ever.

Study locations

3 locations were listed when this page was built. The first 40 are shown.

Indiana University School of Public Health - Bloomington🇺🇸 Bloomington, Indiana, United States
Nana Gletsu Miller, PhDContact
Indiana University Hospital🇺🇸 Indianapolis, Indiana, United States
Nana Gletsu Miller, PhDContact
Purdue University🇺🇸 West Lafayette, Indiana, United States
Cordelia Running, PhDContact