Clinical trial

Effect of TAP Block on GI Function After Sleeve Gastrectomy Using PRO-diGI Scale and Perlas Score

Opening soon · Not applicable · 1 countries · Registry ID NCT07168538

Opening soonNot applicableObservational

What this study is about

This prospective clinical study aims to evaluate the effect of Transversus Abdominis Plane (TAP) block on postoperative gastrointestinal function in patients undergoing laparoscopic sleeve gastrectomy. Gastrointestinal recovery plays a crucial role in patient outcomes after bariatric surgery, and regional anesthesia techniques such as TAP block have been suggested to reduce postoperative pain and opioid consumption, which may influence gut motility. In this study, postoperative gastrointestinal function will be assessed using the validated Patient-Reported Outcome for Dysfunctional Gastrointestinal Motility (PRO-diGI) scale. Additionally, gastric ultrasound will be performed to calculate the Perlas score as an objective marker of gastric emptying and residual volume. These assessments will allow a comprehensive evaluation of both subjective and objective gastrointestinal recovery parameters. The study will include adult patients scheduled for elective laparoscopic sleeve gastrectomy at Elazığ Fethi Sekin City Hospital. Participants will receive standard general anesthesia with or without ultrasound-guided TAP block, and their postoperative recovery will be monitored. Primary outcomes include PRO-diGI scores at defined postoperative intervals, while secondary outcomes include Perlas scores obtained via gastric ultrasonography. The findings from this research are expected to provide valuable insights into the potential benefits of TAP block on gastrointestinal motility and overall recovery after bariatric surgery.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 65 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity, Postoperative Gastrointestinal Dysfunction

Full registry criteria

Inclusion Criteria: * Adult patients aged 18-65 years * Scheduled for primary laparoscopic sleeve gastrectomy (LSG) * Body Mass Index (BMI) ≥ 35 kg/m² * ASA Physical Status II-III * Ability to provide written informed consent Exclusion Criteria: * Previous major abdominal surgery * Known allergy to local anesthetics * Severe hepatic or renal dysfunction * Pregnancy or breastfeeding * Conversion to open surgery during the procedure * Patients refusing TAP block or general anesthesia

Treatments and study arms

TAP Block Group

Procedure

Bilateral ultrasound-guided transversus abdominis plane block performed at the end of surgery using 20 mL of 0.25% bupivacaine per side.

Control Group

Procedure

Standard ERAS-based multimodal analgesia protocol without regional block.

Primary outcomes

Postoperative Gastrointestinal FunctionPostoperative 6, 12, 24, and 48 hours

Description: Assessed using the validated Patient-Reported Outcome for Dysfunction in Gastrointestinal Recovery after Surgery (PRO-diGI) scale, which captures patient-reported symptoms of gastrointestinal motility, including nausea, vomiting, bloating, and oral intake tolerance. The scale ranges from 0 to 15, with higher scores indicating greater gastrointestinal dysfunction and worse postoperative GI function.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Elazığ Fethi Sekin City Hospital🌐 Elâzığ, Turkey (Türkiye)

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Serpil Bayındır, MDContact

Email · Call 05055493582