Clinical trial
Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension
Active, not recruiting · Not applicable · 1 countries · Registry ID NCT07130539
Active, not recruitingNot applicableInterventional
What this study is about
This pilot study examines whether a 4-week diet and exercise intervention can improve blood pressure, heart health, and sleep in physically inactive individuals with high blood pressure and overweight or obesity.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to 74 Years
SexAll
Healthy volunteersNot accepted
ConditionHypertension (HTN), Obesity &Amp; Overweight, Sedentary
Full registry criteria
Inclusion Criteria: * Age 18 to 74 years old * BMI 25 - 39.9 kg/m2 (for measured BMI) * Clinically diagnosed hypertension (physical medical record showing diagnosis of hypertension) with or without current medication use (SPB \< 160 mm Hg, DBP \< 100 mm Hg) * Physically inactive \< 7,500 steps per day (measured on Fitbit over 1-week) * No current injury, illness, or joint issue that prevents participation in exercise * Able to read and speak English * Willingness to participate and give informed written consent * Willingness to share medical record indicating diagnosis of HTN and current medication use Exclusion Criteria: * Pregnant, breastfeeding, lactating * Current smoker * Food allergy or lactose intolerance * Height \> 6 foot 6 inches (78 inches) * Blood pressure ≥ 160/100 mm Hg (Contraindication to exercise testing) * History of diagnosed cardiovascular diseases including heart attack, stroke, irregular heartbeat such as atrial fibrillation, coronary artery or peripheral artery disease, or heart failure * History of liver, kidney, or metabolic disease (including type I or II diabetes) * History of cancer * Diagnosed moderate to severe obstructive sleep apnea, CPAP use, insomnia, h/o other sleep disorder * Night shift and/or rotating shift worker (current or in the past 2 years) * Current use of sleep medications or sleep aids * Excessive alcohol intake - ≥ 8 drinks per week in women, ≥ 15 drinks per week in men * History of gastric bypass or other weight loss surgery * Current use of metformin, insulin, dietary supplements or drugs for glycemic control or weight loss * Weight stable for the last 2 months (\< 5 pounds body weight change) * Currently following a special diet for weight loss (Keto, Atkins, Intermittent Fasting) * A "yes" response to any questions on the PAR-Q (excluding Question 6 on use of BP medications) * Exercise training (≥ 2 days per week structured aerobic and resistance training at gym) * Prior hospitalization for COVID-19 * Any medications or supplements that may alter study outcomes as determined by study PI
Treatments and study arms
MIND HIIT
Other
4 week intervention consisting of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in combination with 3 days per week of High-Intensity Interval Training (HIIT) exercise
Primary outcomes
To determine the feasibility of a 4-week novel lifestyle intervention consisting of a MIND diet and HIIT in adults with HTN and overweight/obesity.From baseline to end of treatment at 4 weeks
Adherence to the lifestyle intervention will be determined by ≥ 75% supervised exercise training visits completed and ≥ 75% dietary compliance.
Study locations
1 locations were listed when this page was built. The first 40 are shown.
Texas Woman's University Houston Center🇺🇸 Houston, Texas, United States