Clinical trial

Sternal Closure in High-BMI Patients: Cable vs Wire

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT07097272

Active, not recruitingNot applicableObservational

What this study is about

This retrospective study compares two sternal closure techniques-standard stainless-steel wires and rigid cable systems-in adult patients with a body mass index (BMI) ≥30 who underwent open-heart surgery between January 1, 2020, and December 31, 2024. The study aims to evaluate the incidence of sternal instability, wound infections, reoperation, and length of stay in the intensive care unit and hospital. Findings may help inform surgical decision-making for high-BMI patients.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 80 Years

SexAll

Healthy volunteersNot accepted

ConditionSternal Wound Complications, Obesity (Body Mass Index >30 kg/m2), Median Sternotomy, Cardiac Surgery

Full registry criteria

Inclusion Criteria: 1. Age ≥18 years 2. Body Mass Index (BMI) ≥30 kg/m² 3. Underwent primary open-heart surgery via median sternotomy 4. Sternal closure performed with either standard stainless-steel wire or multifilament sternal cable system 5. Complete and accessible perioperative clinical records Exclusion Criteria: 1. Age ≥80 years 2. End-stage renal disease or chronic hemodialysis 3. Redo sternotomy 4. Early postoperative re-exploration (within 7 days) 5. Mediastinitis prior to index discharge 6. Diabetic patients with bilateral internal mammary artery (IMA) harvest 7. Diagnosed osteoporosis 8. Chronic obstructive pulmonary disease (FEV₁ \<80% and FEV₁/FVC \<70%)

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Incidence of Sternal Instability and Major Wound Complications90 days after surgery

This outcome measures the rate of sternal instability (e.g., dehiscence, nonunion, displacement requiring intervention) and major sternal wound complications (e.g., deep sternal wound infection, mediastinitis, or reoperation for closure failure) in patients with BMI ≥30 undergoing open-heart surgery. The results will be compared between patients whose sternum was closed with standard stainless-steel wire versus those treated with a multifilament sternal cable system.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Samsun University Faculty of medicine🌐 Samsun, Turkey (Türkiye)

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