Clinical trial

Muscle Quality and Subcutaneous Adipose Tissue in the Rectus Femoris and Rectus Abdominis Muscles: Ultrasound Evaluation and Functional Correlation in Older Adults

Opening soon · Not applicable · 1 countries · Registry ID NCT07069777

Opening soonNot applicableObservational

What this study is about

The goal of this observational, cross-sectional study is to examine the relationship between body composition and muscle quality in women over the afe of 65. The main question it aims to answer is: How are ultrasound-based measurements of muscle and fat tissue related to functional performance in older women?

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age65 Years to Not listed

SexFemale

Healthy volunteersNot listed

ConditionUltrasound, Sarcopenia, Obesity

Full registry criteria

Inclusion Criteria: * Aged ≥ 65 years and living in the community. * Female sex. * Enrolled as a participant in PReGe program. Exclusion Criteria: * Recent surgery (\<6 months) involving the abdomen or lower extremities. * Presence of methal prostheses or implants in the thigh or abdoinal region. * Diagnosed neuromuscular disease (e.g., myopathies, advanced Parkinson's disease.) * Musculoskeletal disorders that impair basic mobility or prevent functional testing. * Acute illness or clinical decompensation at the time of assessment. * Unintentional weight loss \> 5 kg within the past month (suggestive of cachexia risk). * Presence of active abdominal hernias or severe diastasis recti.

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Ultrasound Assessment of the Rectus Femoris MuscleAt a single assessment visit

The rectus femoris muscle was assessed using B-mode ultrasound imaging, following SARCUS group recommendations. Participants were positioned supine for 5 minutes prior to imaging to ensure fluid redistribution. A linear transducer (12 MHz) was used with neutral probe angle and minimal pressure. The anatomical landmark was the midpoint between the greater trochanter and the upper pole of the patella. Measurements included muscle thickness, pennation angle, fascicle length, echo intensity, cross-sectional area, and subcutaneous fat thickness. Images were taken in both transverse and longitudinal planes. Three measurements were taken per view to ensure accuracy.

Ultrasound Assessment of the Rectus Abdominis MuscleAt a single assessment visit

The rectus abdominis muscle was assessed using the same ultrasound equipment and imaging protocol as for the rectus femoris. The anatomical reference point was located 3 cm lateral to the umbilicus, as per SARCUS group guidance. Images were acquired in both transverse and longitudinal planes. Measurements included muscle thickness, echo intensity, anatomical cross-sectional area, and subcutaneous fat thickness. Three measurements were taken per view to ensure reliability.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

University of Salamanca🇪🇸 Salamanca, Salamanca, Spain

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Roberto Méndez Sánchez, PhDContact

Email · Call +34 696503947