Clinical trial

Impact of Chronotype-Based Time-Restricted Eating on Visceral Fat and Metabolic Health in Physically Inactive Adults With Central Obesity

Invitation only · Not applicable · 1 countries · Registry ID NCT07062315

Invitation onlyNot applicableInterventional

What this study is about

Time-restricted eating (TRE) has gained attention as a promising dietary strategy for enhancing body composition and metabolic health. This innovative eating pattern involves confining daily food intake to a specific window, typically spanning 6-10 hours. Given the lack of consensus on the optimal TRE strategy, this research explores whether tailoring eating windows to individual chronotypes enhances TRE outcomes. This randomized controlled trial aims to evaluate the effects of chronotype-matched versus chronotype-unmatched TRE protocols, compared to a control group, over a 12-week period on visceral fat mass and other metabolic health outcomes in physically inactive adults with central obesity. Additionally, the study seeks to determine whether chronotype-matched TRE offers greater benefits in terms of visceral fat reduction and metabolic improvements compared to chronotype-unmatched TRE. Assessments will be conducted at baseline, and after the 12-week intervention.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 65 Years
SexAll
Healthy volunteersNot accepted
ConditionCentral Obesity, Time Restricted Eating

Full registry criteria

Inclusion Criteria: 1. Chinese adults, male or female, aged between 18-65 years old; 2. BMI of 23 kg/m² or higher, with a waist circumference exceeding 80 cm for females and 90 cm for males; 3. Weight stability for at least three months prior to the start of the study; 4. Physically inactive, indicated by not meeting established WHO guidelines on physical activity and sedentary behavior (i.e., at least 150-300 minutes of moderate-intensity or at least 75-150 minutes of vigorous-intensity aerobic exercise; or an equivalent combination of moderate and vigorous-intensity activity throughout the week; 5. Baseline eating duration exceeding 10 hours per day; 6. Identified as either early or late chronotypes (Morningness-Eveningness Questionnaire) Exclusion Criteria: 1. Individuals currently or chronically receiving pharmacological treatment for hypertension, diabetes, weight loss, or other metabolic conditions; 2. Night shift workers; 3. Individuals with eating disorders; 4. Female participants who are breast-feeding, pregnant, or attempting to become pregnant; 5. Individuals currently participating in other weight-management programs or following other prescribed diet programs.

Treatments and study arms

Chronotype-matched time-restricted eating

Behavioral

A 12 weeks time-restricted eating intervention that match participants' chronotype

Chronotype-unmatched time-restricted eating

Behavioral

A 12 weeks time-restricted eating intervention that not match participants' chronotype

Primary outcomes

Visceral fat mass12 weeks

Visceral fat mass will be assessed using Magnetic Resonance Imaging (MRI)

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Department of Sports Science and Physical Education, The Chinese University of Hong Kong🇨🇳 Hong Kong, China