Clinical trial

Dual-chamber Patient-controlled Analgesia for Postoperative Recovery

Recruiting now · Not applicable · 1 countries · Registry ID NCT07051109

Recruiting nowNot applicableInterventional

What this study is about

Postoperative nausea and vomiting (PONV) are the most common complications that can occur after general anesthesia. Postoperative use of opioids and morbid obesity have been reported as risk factors of PONV. In this study, the investigators aimed to compare the degree of postoperative side effects and pain control when an intravenous patient-controlled analgesia combining fentanyl and ketorolac via a dual-chamber device was provided to participants undergoing laparoscopic sleeve gastrectomy.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age19 Years to 65 Years

SexFemale

Healthy volunteersNot accepted

ConditionMorbid Obesity, PCA, Analgesia, PONV

Full registry criteria

Inclusion Criteria: * Adult females aged 19 to 65 years * American Society of Anesthesiologists physical status (ASA class) 1 to 3 * Patients scheduled for laparoscopic sleeve gastrectomy under general anesthesia * Patients requesting the use of IV-PCA after surgery Exclusion Criteria: * Patients with hypersensitivity to the drugs used in this study (Ketorolac, Fentanyl) * Patients with alcohol or drug dependence, long-term use of opioids or analgesics * Patients with liver disease or renal failure * Patients with peptic ulcer, patients with gastrointestinal bleeding predisposition * Patients with suspected cerebrovascular hemorrhage, organic disorders of the head related to increased intracranial pressure * Patients with bronchial asthma or bronchospasm symptoms * Patients with severe respiratory depression * Nasal polyps, angioedema * Patients with or history of convulsive disease * Patients for whom the use of neuromuscular blocking agents is contraindicated

Treatments and study arms

multimodal analgesia via dual-chamber PCA

Device

combination of fentanyl and ketorolac through dual-chamber PCA

single regimen (only fentanyl)

Device

fentanyl only through dual-chamber PCA

Primary outcomes

postoperative nausea and vomittingpostoperative 1 day

The Quality of Recovery score 15

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Seoul National University Bundang Hospital🇰🇷 Seongnam-si, Gyunggi-do, South Korea

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Insun Park, M.D./Ph.D.Contact

Email · Call 823178777499