Active, not recruitingNot applicableObservational
What this study is about
Mauritius is located in the southern Indian Ocean with a population of 1.3 million in 2023. Mauritius is a multiethnic nation with 68% South Asian, 27% African (Creole), 3% Chinese and 2% Franco Mauritians. Seven population-based cross-sectional surveys using standardised protocols were conducted between 1987 and 2021). The participation rate has been over 85% in each survey. At each survey, participants were interviewed about living conditions, lifestyle and health, and anthropometry and blood pressure were measured. Biochemistry including lipids and an oral glucose tolerance test (OGTT) were performed Electrocardiograms (ECG) were recorded in participants aged 35 years and older. Previous participants were followed up in 2007 and 92% were successfully traced. Studies with identical methodology have been performed on the neighbouring island Rodrigues where the majority of the population are Creoles.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age25 Years to 74 Years
SexAll
Healthy volunteersAccepted
ConditionDiabete Mellitus, Cardiovascular Disease Risk Factor, Ischemic Cardiovascular Disease, Hypertension, Obesity &Amp; Overweight
Full registry criteria
In short: Inclusion * Men and women * Randomly selected population-based samples (details see below) * Target age from 25 to 74 years Exclusion * Not living in the study area * Age outside the age-range In detail: Inclusion Criteria In 1987, 10 randomly selected (with probability proportional to size) population clusters and a purposely selected area of Chinatown in the capital, Port Louis, were surveyed (age range 25-74), and all eligible residents were invited to participate.2 In 1992 and 1998, the same clusters were resurveyed as well as an additional three clusters selected to assess if trends in disease and risk factor distribution observed in the study cohort also occurred in independent clusters (age range 25 years and older). In 1998, the Chinatown cluster was not surveyed. Altogether, 9,559 individuals participated in the first three surveys and 60% of participants took part in more than one survey. In 2004, a new study was performed, with similar methodology. In 2009, nine index clusters were chosen with one randomly selected from each of the nine districts in Mauritius. Then, two neighbouring clusters were chosen surrounding the index cluster to form a "super cluster." From this super cluster, one in three households was randomly selected and one adult per household was invited to participate.5 The same methodology was used in 2015 and in 2021 with new randomly chosen clusters forming "super cluster" as in 2009. In addition, a random sample from the 1998 survey was invited for a resurvey in 2015. Participation rate has been over 85% in each survey. No sampling weights were used. Same methodology was used in Rodrigues. Exclusion Criteria Outside age-range and not being randomly selected.
Primary outcomes
MortalityUp to 20 years from the baseline surveyAccording to household interviews, death certificates from central registers at Ministry of Health and Wellness. 1. Household interviews: "Is the participant alive? If dead, do you have a copy of the death certificate? When did the participant die?" 2. Central registers: Vital status, if dead, date and cause of death from death certificates" Combining 1 and 2 will give date and cause of death. Absolute numbers and mortality rates will be reported for all and in subgroups i.e. sex, age-strata, ethnicity.
