Clinical trial

Lung Ultrasound Evaluation of the Effects of PEEP and Recruitment Strategies Adjusted for Intraoperative Dynamic Compliance on Postoperative Respiratory Complications in Obese Patients Planned for Laparoscopic Surgery

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT06994780

Active, not recruitingNot applicableInterventional

What this study is about

This study aims to investigate the effects of the personalized application of respiratory pressures applied to patients undergoing laparoscopic bariatric surgery when they are connected to a ventilator under general anesthesia, on the postoperative period. The effects of the ventilation practices that are fixed in routine practice and revised according to various variables during the surgery during artificial respiration after intubation under general anesthesia will be examined with ultrasonography. No change will be made to the routine anesthesia practice for this purpose, the pressure values in the ventilator under general anesthesia will be adjusted during the surgery within the framework of the values used in anesthesia practice. After the surgery, the lung area will be examined with ultrasound in the recovery unit and the findings will be recorded. This study does not have any undesirable effects or risks. This study does not include any interventional procedures.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexAll

Healthy volunteersAccepted

ConditionObesity, Postoperative Bariatric Surgery, Laparoscopic Surgery, Individualized PEEP Treatment Strategy

Full registry criteria

Inclusion Criteria: \- Patients over the age of 18, with a body mass index of 35 and above, and who are scheduled for laparoscopic bariatric surgery will be included in our study. Exclusion Criteria: * Patients with advanced COPD, * Patients with a history of pneumothorax, * Patients with lung bullae, * Patients who have undergone thoracic surgery, * Patients with a diagnosis of major cardiac disease (valve diseases, heart failure, systolic dysfunction), * Patients with severe respiratory failure, * Patients with previous pulmonary surgery will not be included in the study.

Treatments and study arms

dynamic compliance guided PEEP titration

Procedure

In order to find the individualized optimal PEEP value, PEEP will be increased at 2-minute intervals with a maximum peak pressure of 45 cmH2O and a driving pressure of 15 cmH2O. Recruitment will be performed. When the target is reached, the PEEP value will be adjusted to the value at which the highest dynamic compliance is achieved by decreasing it.

Primary outcomes

Modified lung ultrasound scoreAt the end of the surgery, a modified lung ultrasonography will be performed in the recovery unit.

Each hemithorax will be divided into 6 regions by 3 vertical lines from the anterior axillary, parasternal and posterior axillary lines; 2 horizontal imaginary lines 1 cm above the nipple and at the level of the diaphragm. Each region will be evaluated in terms of lung sliding motion, A lines, B lines, consolidation, air bronchograms, pleural effusion and pneumothorax, and the total score calculated for 12 regions will be recorded and compared using the scoring system defined by Monastesse et al (2017).

Study locations

2 locations were listed when this page was built. The first 40 are shown.

Marmara University Pendik Training and Reseach Hospital🌐 Istanbul, Pendik, Turkey (Türkiye)

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Marmara University Pendik Training and Research Hospital🌐 Istanbul, pendik, Turkey (Türkiye)

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