Clinical trial
Lactobacillus Plantarum and Hormonal Regulation in Obese Women
Recruiting now · Not applicable · 1 countries · Registry ID NCT06987279
Recruiting nowNot applicableInterventional
What this study is about
To evaluate the regulatory effect of Lactobacillus plantans Lp90 formula on visceral fat metabolism and sex hormone balance in obese women.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to 40 Years
SexFemale
Healthy volunteersAccepted
ConditionObesity, Women
Full registry criteria
Inclusion Criteria: 1. Age: 18 to 40 years old, female, BMI ≥ 25 kg/m2. 2. Be willing to receive follow-up during the intervention period. 3. Be willing to provide two blood, urine and fecal samples during the intervention period. 4. Be willing to take the compound probiotics by oneself every day during the intervention period. 5. Have good hearing and be able to hear and understand all instructions during the intervention period. \- Exclusion Criteria: 1. Suffering from digestive system diseases, mainly gastrointestinal diseases (celiac disease, ulcerative colitis, Crohn's disease). 2. Suffering from severe neurological disorders (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, long-term coma - excluding general anesthesia). 3. Have received/are currently receiving treatment for the following mental illnesses: alcohol/drug/substance abuse dependence, schizophrenia, psychosis, bipolar disorder. 4. Take medication for depression or low mood. 5. Suffering from internal organ failure (such as heart, liver or kidney failure, etc.). 6. Have received radiotherapy or chemotherapy in the past. 7. Have received general anesthesia surgery/procedures within the past three years, or plan to receive general anesthesia procedures/surgeries within the next three months during this trial. 8. Have suffered from hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past. \-
Treatments and study arms
Probiotic
Dietary Supplement
The trial period of this study is 3 months, and each patient will undergo 4 visits (in month 0, month 1, month 2, and month 3).
Maltodextrin
Dietary Supplement
The trial period of this study is 3 months, and each patient will undergo 4 visits (in month 0, month 1, month 2, and month 3).
Primary outcomes
The changes of estradiol before and after the intervention0, 1, 2, 3 months
The serum estrogen content of the subjects before and after the intervention was detected by enzyme-linked immunosorbent assay.
Study locations
1 locations were listed when this page was built. The first 40 are shown.
Fuwai Central-China Cardiovascular Hospital🇨🇳 Zhengzhou, Henan, China
Yingpeng TianContact