Clinical trial

Dietary Inflammatory Potential in Young Pleople With Obesity

Opening soon · Not applicable · 0 countries · Registry ID NCT06971666

Opening soonNot applicableObservational

What this study is about

The increase in adipose tissue in the young population is one of the most important and worrying public health problems because it persists in adulthood, constituting a risk factor for chronic degenerative diseases with social, economic, and environmental effects. The etiology of obesity is multifactorial and is associated with a low-intensity chronic inflammation process. Therefore, side effects of the digestive, nervous, endocrine, and immunological levels are closely related. Thus, understanding the impact of dietary components on the immune response and the pathophysiological complications of obesity will strengthen information on nutritional patterns with lower inflammatory implications.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 24 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity, Dietary Inflammatory Index (DII)

Full registry criteria

Inclusion Criteria: * Both sexes with no gender exclusion * Age between 18 and 24 years * Body Mass Index (BMI) ≥ 30 kg/m² * Signed informed consent Exclusion Criteria: * Pregnancy or expected pregnancy within the next month * Women who are breastfeeding * Diagnosed conditions such as: diabetes mellitus, hypertension, renal or hepatic insufficiency, infectious diseases, inflammatory diseases, or any neoplastic disease * Conditions with dietary restrictions, such as celiac disease or history of gastric bypass surgery * Active alcoholism with a daily intake exceeding 50 g/day * Significant anticipated changes in diet or exercise within 15 days prior to the study's start * History of drug or medication abuse * Eating disorders * Participation in any study involving investigational products within the 3 months prior to the start of the study * Treatment with anti-inflammatory drugs, antibiotics, and/or antidepressants in the month prior to the study's start * Consumption of nutraceuticals containing prebiotics, probiotics, or immunomodulators within 15 days prior to the study's start * Individuals who choose to discontinue participation after the data collection process has started. * Individuals who do not consent to the collection of any of the required samples (blood, diet, or stool) during the data collection phase.

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Dietary Assessment1.5 years

Dietary intake will be estimated from a validated semiquantitative food frequency questionnaire (FFQ) that represents food consumption for the last 12 months. For each item, regular portion size will be established, and then frequencies of consumption will be available, ranging from "never" to "6 or more times/day". Energy and nutrient intakes will be obtained by multiplying the frequency by the serving size from Mexican food composition.

Dietary Inflammatory Index, DII1.5 years

For the Dietary Inflammatory index, 45 food parameters related (positively or negatively) to inflammatory markers such as IL beta, IL4, IL6, IL10, TNF alpha, and CRP will be used. The score for each dietary parameter will be multiplied by each participant's intake, resulting in a numerical score ranging from -8 to +8.

Dietary Inflammatory Potential, DIP1.5 years

The DIP will be obtained by analyzing the Dietary assessment and the Dietary Inflammatory Index intake, which will then be converted to a percentile score of 2 and subtracted by 1. The percentile score will be multiplied by the inflammatory effect score. All food parameters sill be summed to create the score. The score will be in quartiles: Q1, highly anti-inflammatory, Q2, anti-inflammatory, Q3, inflammatory; and Q4, highly inflammatory

Study locations

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No public site location was included in this record. Check the original registry for updates.