Clinical trial

Evaluation of Molecular Hydrogen Supplementation to Enhance the Efficacy of Weight Loss Retreat in Overweight and Obese Adolescents

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT06961110

Active, not recruitingNot applicableInterventional

What this study is about

This randomized controlled trial evaluates whether molecular hydrogen supplementation enhances the effectiveness of a 4-week weight loss retreat in overweight and obese adolescents. Outcome measures include: body composition, physical status, blood samples (insulin sensitivity, lipid profiles, markers of oxidative stress and inflammation) and autonomic nervous system function.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age11 Years to 18 Years

SexAll

Healthy volunteersNot accepted

ConditionBody Composition, Fitness, Insulin Sensitivity, Lipid Profile, Oxidative Stress, Inflammation, Autonomic Nervous System Activity

Full registry criteria

Inclusion Criteria: * Body mass index indicating overweight or obesity, as determined according to the World Health Organization's international percentile charts for children aged 5-19 years. * Presence of a regular menstrual cycle in female participants. * Signed informed consent from the legal representative. Exclusion Criteria: * High blood pressure. * Dyslipoproteinemia. * Cardio-respiratory disorders. * Musculoskeletal disorders. * Use of any medications regulating heart rhythm or the neurovegetative and hormonal system.

Treatments and study arms

Hydrogen-rich water

Dietary Supplement

Hydrogen-rich water with molecular hydrogen concentration 1.2-1.6 ppm. No added sugar or preservatives.

Placebo

Dietary Supplement

Drinking water with molecular hydrogen concentration 0.0 ppm. No added sugar or preservatives.

Primary outcomes

Body mass indexBaseline and 4 weeks

Body mass index is calculated as the ratio of body mass (kg) to the square of body height (m2). Body mass is measured using a digital scale to the nearest 0.1 kg and body height is measured using a stadiometer to the nearest 1 cm.

Six-minute walk testBaseline and 4 weeks

Six-minute walk test is measured by recording the total distance the participant is able to walk on a flat surface within six minutes. The participant is instructed to walk at his/her own pace in order to walk as far as possible in the given time.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Palacky University, Faculty of Physical Culture🇨🇿 Olomouc, Czech Republic, Czechia

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