Clinical trial
Building Research for Intervention Development in Gliosis and Eating Habits
Recruiting now · Not applicable · 1 countries · Registry ID NCT06870578
Recruiting nowNot applicableInterventional
What this study is about
The goal of this study is to 1) use magnetic resonance imaging (MRI) to evaluate the effect of nutritious foods on inflammation in the human hypothalamus of children and 2) assess the feasibility and acceptability of nutritious food feeding intervention strategies in children with overweight or obesity.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age9 Years to Not listed
SexAll
Healthy volunteersAccepted
ConditionGliosis, Child Obesity, Eating
Full registry criteria
Inclusion Criteria: * Study1: Adult caregiver and Child age 9-11y. Willing to come to in-person focus group * Study 2: Age 9-11y, BMI ≥85th and ≤95th percentile for age and sex * Study 3:Adult caregiver with child who qualify for free or reduced-cost lunch in WA State. Child age 9-11y and with overweight. Exclusion Criteria (study 1 child participants and study 3 criteria for children of adult participants): * Significant health conditions including type 2 diabetes * History of major weight loss or eating disorder * Current use of medications known to alter appetite or body weight (e.g., stimulants for ADHD) * Documented cognitive disorder * Severe food allergies, vegetarian, or vegan (Study 1 only) * Unable to make the session date Exclusion Criteria (study 2, child participants): * Significant health conditions including type 2 diabetes * History of major weight loss or eating disorder * Current use of medications known to alter appetite or body weight (e.g., stimulants for ADHD) * Documented cognitive disorder * MRI contraindication (e.g., braces, claustrophobia) * Weight \>330 pounds (MRI limit) * Severe food allergies, vegetarian, or vegan * Currently in formal weight loss program
Treatments and study arms
Diet modification
Other
In Study 2 only, children will be provided all meals for a 7-day period. Meals will consist of nutritious foods, calories provided will exceed the child's estimated daily caloric need, and children will be asked to consume meals ad libitum.
Primary outcomes
T2 relaxation time by brain MRI7 days of diet intervention
Study locations
1 locations were listed when this page was built. The first 40 are shown.
University of Washington🇺🇸 Seattle, Washington, United States
BRIDGE StudyContact