Clinical trial

Outcomes Of Laparoscopic Sleeve Gastrectomy In Patients With Hypothyroidism And Depression

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT06859320

Active, not recruitingNot applicableInterventional

What this study is about

Sleeve gastrectomy (SG) continues to be one of the most popular bariatric procedures all over the world. It has been established that obesity is a predisposing factor for several comorbidities, including life-threatening conditions. Many studies have discussed the impact of sleeve gastrectomy on TSH level. But, since most obese patients have some sort of depression, we will try to study the impact of sleeve gastrectomy, depression and hypothyroidism on each other.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 60 Years

SexAll

Healthy volunteersNot accepted

ConditionObesity and Obesity-related Medical Conditions

Full registry criteria

Inclusion Criteria: * obese patients with depression and hypothyroidism controlled by medical treatment candidate for sleeve gastrectomy Exclusion Criteria: * patients less than 18 or above 60 * other psychiatric or medical disorders. * patients not fit for surgery * un controlled patients

Treatments and study arms

laparoscopic sleeve gastrectomy

Procedure

laparoscopic sleeve gastrectomy is one of the popular bariatric surgeries known for weight reduction

Primary outcomes

thyroid function testsfrom one day to one year after surgery

TSH,T3,T4 are measured pre and post operative

depressionfrom one day to one year after surgery

depression status is compared pre-operative and post-operative using depression questionnaire (PHQ-9)( patient health questionnaire-9)

weightfrom one day to one year after surgery

weight of the patient will be measured in Kg using weight scale

dose of thyroid replacement therapymonthly from one day to one year post surgery.

the dose of L-thyroxin is monitored in microgrames

gasteric leakagefrom one day to 1 week post-surgery

leakage after surgery from staple line measured in ml in the drain

wound infectionfrom one day to 2 weeks post-surgery

wound infection will be identified by pus in the drain or in the wound

Study locations

2 locations were listed when this page was built. The first 40 are shown.

Faculty of Medicine🇪🇬 Zagazig, Sharqia Province, Egypt

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Zagazig University Hospitals🇪🇬 Zagazig, Egypt

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