Clinical trial

Identification of Microplastics in Liver, Stomach, Blood, and Feces of Obese Patients and Their Association Analysis with Macrogenomics and Metabolomics.

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT06826586

Active, not recruitingNot applicableObservational

What this study is about

The aim of this study was to identify and quantify microplastics in the stomach, liver, feces, and blood of obese patients to be treated with bariatric surgery by using a variety of advanced analytical techniques to explore the association between obesity and visceral microplastics, and to investigate the effects of microplastics on the visceral microbiota and metabolic profiles of obese patients by combining the macro-genomic and metabolomics approaches.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexAll

Healthy volunteersNot accepted

ConditionObesity and Overweight

Full registry criteria

Inclusion Criteria: * Age ≥18 years old; * BMI ≧30; * proposed to undergo bariatric surgery and need to remove part of the liver tissue for fatty liver test; * complete clinical data and basic information; * willing to participate in the study and sign the informed consent form. Exclusion Criteria: * Receive chemotherapy, radiotherapy, immunotherapy; * have other history of digestive diseases; * combined with malignant tumors; * have serious cardiorespiratory insufficiency and other systemic diseases that affect the choice of treatment plan; * not willing to participate in this study.

Treatments and study arms

Measuring the microplastics

Diagnostic Test

Measuring the type, nature, and abundance of microplastics in stomach, liver, feces, and blood

Primary outcomes

Differences in microbial communitiesFrom the diagnosis of obesity, through study completion, an average of 1 year.

Differences in different microbial communities in the stomach, liver, feces, and blood of obese patients

Study locations

1 locations were listed when this page was built. The first 40 are shown.

The First Affiliated Hospital of Chongqing Medical University🇨🇳 Chongqing, Chongqing Municipality, China

Open map