Clinical trial

EFFECT OF PYRAMIDAL TRAINING ON EPICARDIAL FAT FOR CORONARY ARTERY DISEASE PREVENTION

Opening soon · Not applicable · 1 countries · Registry ID NCT06799104

Opening soonNot applicableInterventional

What this study is about

To show the effect of pyramidal training for coronary artery disease prevention on: -Epicardial fat, BMI, Waist circumference (WC), Lipid profile, Quality of life and Mediterranean Diet Adherence.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age30 Years to 40 Years

SexFemale

Healthy volunteersNot accepted

ConditionCoronary Artery Disease, Class I Obesity

Full registry criteria

Inclusion Criteria: * Fifty females' patients with class I obesity (BMI 30 to 34.9 kg/m2, Waist circumference \> 88 cm). * Their age ranges from 30-40 years old. * Dyslipidemia and lipid profile as follow (total cholesterol high: 240 mg/dl, HDL less than 40 mg/dl, LDL high: 160-189 mg/dL and triglycerides high: 200-499 mg/dl). * All patients will be clinically and medically stable when attending the study. Exclusion Criteria: * Patients with conditions will be excluded such as: * Musculoskeletal problems. * Chronic pulmonary disease. * Missed more than two weeks of the program or want to terminate the program. * Unstable angina. * Acute illness. * Uncontrolled cardiac arrhythmia. * Decompensated heart failure. * Cognitive impairment or mental disorders. * Systolic blood pressure higher than 180, and/or diastolic blood pressure over 100mmHg. * DVT. * Multiple food allergies/intolerances or gastrointestinal difficulties of the prescribed diet. * Cancer (have special nutritional and training needs).

Treatments and study arms

Pyramidal training

Other

Pyramidal training prescription:Mode of exercise: aerobic interval training. Intensity: ranging from 20-80% from THR. Duration: 40 minutes per session.Frequency: Three sessions per week for 12 weeks. The course of the program will be 2 sets of pyramidal training with 10 minutes for rest between them. Each set will be 5 levels of incremental and 5 levels of decremental aerobic exercise and each level 2 minutes on a treadmill. 1. Level one: will be set as a 20% walking of Karvonen formula. 2. Level two: will be set as a 30% running of Karvonen formula. 3. Level three: will be set as a 50%running of Karvonen formula. 4. Level four: will be set as a 70% running of Karvonen formula. 5. Level five: will be set as a 80% running of Karvonen formula.

Mediterranean diet

Other

Mediterranean diet: Meal Composition Main meals consumed daily should be a combination of three elements: cereals, vegetables and fruits, and a small quantity of legumes, beans or other (though not in every meal). Cereals in the form of bread, pasta, rice, couscous or bulgur (cracked wheat) should be consumed as one-two servings per meal. Vegetable consumption should amount to two or more servings per day, in raw form for at least one of the two main meals (lunch and dinner). Fruit should be considered as the primary form of dessert, with one-two servings per meal.

Primary outcomes

Epicardial adipose tissue thickness.12 weeks

The echo measurements for EATT will be taken in standard parasternal view in the left lateral decubitus position by an experienced cardiologist, and the mean values between long- and short-axis views will record. The EAT is identify as the echo-free space between the outer wall of the myocardium and the visceral layer of the pericardium. The thickness is measure perpendicularly on the free wall of the right ventricle at end systole in three to ten cardiac cycles

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Cairo University🇪🇬 Cairo, Giza Governorate, Egypt

Open map