Clinical trial

Study of Patients Being Treated With Anti-obesity Medication

Recruiting now · Not applicable · 1 countries · Registry ID NCT06790160

Recruiting nowNot applicableObservational

What this study is about

The goal of this observational study is to learn about the real-world effects of selected obesity medications in adults undergoing medical weight management. The main outcomes of interest are changes in body composition, routine clinical markers, muscular performance, and nutritional intake over the course of treatment. Additionally, the influence of lifestyle factors on changes in these outcome variables will be examined. Participants beginning treatment with selected obesity medications will undergo periodic body composition and muscular performance testing, as well as complete online surveys about their nutritional intake and physical activity and exercise participation. Additionally, routinely collected clinical information will be evaluated.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexAll

Healthy volunteersNot accepted

ConditionObesity and Overweight

Full registry criteria

Inclusion Criteria: * Patient who is beginning treatment through Vineyard Virtual Health Clinic using semaglutide or tirzepatide. While the physician will individualize the treatment plans, the criteria for these medications will include, at a minimum: (A) a body mass index ≥30 kg/m2; OR (B) a BMI ≥27 kg/m2 plus at least one comorbidity. * Patient who lives in drivable proximity to a city with an accepted DXA testing facility and is willing to report to the facility for periodic body composition testing. Exclusion Criteria: * Patients with type 2 diabetes. * Patients who report not being willing or able to complete the assessments included in this research study. * Patients who are currently pregnant or trying to become pregnant.

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Change in Total Lean Soft TissueFrom baseline assessment to last available time point (follow-up assessments conducted ~6 months and ~17 months after baseline).

Change in total lean soft tissue assessed by dual-energy X-ray absorptiometry.

Change in Appendicular Lean Soft TissueFrom baseline assessment to last available time point (follow-up assessments conducted ~6 months and ~17 months after baseline).

Change in appendicular lean soft tissue assessed by dual-energy X-ray absorptiometry.

Change in Total Fat MassFrom baseline assessment to last available time point (follow-up assessments conducted ~6 months and ~17 months after baseline).

Change in total fat mass assessed by dual-energy X-ray absorptiometry.

Change in Handgrip StrengthFrom baseline assessment to last available time point (follow-up assessments conducted ~3, ~6, and ~17 months after baseline).

Change in maximal handgrip strength as determined by a handgrip dynamometer.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Texas Tech University🇺🇸 Lubbock, Texas, United States

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Grant TinsleyContact

Email · Call 806-834-5895